Copper-Free Palladium-Catalyzed Sonogashira Coupling−Annulation: Efficient One-Pot Synthesis of Functionalized Pyrano[4,3-b]quinolines from 2-Chloro-3-formylquinolines

2009 ◽  
Vol 74 (15) ◽  
pp. 5664-5666 ◽  
Author(s):  
Atish Chandra ◽  
Bhawana Singh ◽  
Ranjana S. Khanna ◽  
Radhey M. Singh
Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5149-5158
Author(s):  
Alavala Krishna Reddy ◽  
Gedu Satyanarayana

Palladium-catalyzed copper-free Sonogashira coupling of 2-bromocarbonyls is presented. This method afforded the 2-alkynylaryl carbonyls, useful synthons for the accomplishment of many carbocyclic and heterocyclic motifs. Significantly, the strategy was extended to the one-pot synthesis of isobenzofurans via reduction followed by intramolecular 5-exo-dig cyclization.


2019 ◽  
Vol 17 (17) ◽  
pp. 4281-4290 ◽  
Author(s):  
Hitesh Kumar Saini ◽  
Shiv Dhiman ◽  
Nitesh Kumar Nandwana ◽  
Rangan Krishnan ◽  
Anil Kumar

A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(ii)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand free Heck reaction.


2017 ◽  
Vol 2017 (27) ◽  
pp. 4026-4034 ◽  
Author(s):  
Mirza Feroz Baig ◽  
Siddiq Pasha Shaik ◽  
Namballa Hari Krishna ◽  
Neeraj Kumar Chouhan ◽  
Abdullah Alarifi ◽  
...  

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