Application of the Ugi Reaction for the One-Pot Synthesis of Uracil Polyoxin C Analogues

2009 ◽  
Vol 74 (13) ◽  
pp. 4870-4873 ◽  
Author(s):  
Andrew Plant ◽  
Peter Thompson ◽  
David M. Williams
ChemInform ◽  
2011 ◽  
Vol 42 (27) ◽  
pp. no-no
Author(s):  
Christopher P. Gordon ◽  
Kelly A. Young ◽  
Lacey Hizartzidis ◽  
Fiona M. Deane ◽  
Adam McCluskey

2011 ◽  
Vol 9 (5) ◽  
pp. 1419 ◽  
Author(s):  
Christopher P. Gordon ◽  
Kelly A. Young ◽  
Lacey Hizartzidis ◽  
Fiona M. Deane ◽  
Adam McCluskey

Synlett ◽  
2017 ◽  
Vol 28 (10) ◽  
pp. 1214-1218 ◽  
Author(s):  
Sorour Ramezanpour ◽  
Zahra Bigdeli ◽  
Nahid Alavijeh ◽  
Frank Rominger

The use of saccharin as a replacement for the carboxylic acid component in an Ugi multicomponent condensation leading to [(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]acetamide (3-iminosaccharin) derivatives is described for the first time.


2020 ◽  
Vol 24 (20) ◽  
pp. 2341-2355
Author(s):  
Thaipparambil Aneeja ◽  
Sankaran Radhika ◽  
Mohan Neetha ◽  
Gopinathan Anilkumar

One-pot syntheses are a simple, efficient and easy methodology, which are widely used for the synthesis of organic compounds. Imidazoline is a valuable heterocyclic moiety used as a synthetic intermediate, chiral auxiliary, chiral catalyst and a ligand for asymmetric catalysis. Imidazole is a fundamental unit of biomolecules that can be easily prepared from imidazolines. The one-pot method is an impressive approach to synthesize organic compounds as it minimizes the reaction time, separation procedures, and ecological impact. Many significant one-pot methods such as N-bromosuccinimide mediated reaction, ring-opening of tetrahydrofuran, triflic anhydrate mediated reaction, etc. were reported for imidazoline synthesis. This review describes an overview of the one-pot synthesis of imidazolines and covers literature up to 2020.


2001 ◽  
Vol 2001 (4) ◽  
pp. 160-161 ◽  
Author(s):  
Hongyun Guo ◽  
Yunfa Zheng ◽  
Yongmin Zhang

α-Selenonitriles, α-selenoesters, and asymmetrical selenides can be readily obtained from the one-pot reaction of diselenides and active organic halides by a Sm/ZnCl2 system in DMF-H2O.


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