Metal–Ligand Binding Interactions in Rhodium/Palladium-Catalyzed Synthesis of Dihydroquinolines

2014 ◽  
Vol 79 (24) ◽  
pp. 12159-12176 ◽  
Author(s):  
Lei Zhang ◽  
Jane Panteleev ◽  
Mark Lautens
Keyword(s):  
Ligand Binding ◽  
Binding Interactions ◽  
Palladium Catalyzed ◽  
Metal Ligand

Impact of Surface Adsorption on Metal–Ligand Binding of Phenanthrolines

2021 ◽  
Author(s):  
Johnson Dalmieda ◽  
Ana Zubiarrain-Laserna ◽  
Dipankar Saha ◽  
Ponnambalam Ravi Selvaganapathy ◽  
Peter Kruse
Keyword(s):  
Ligand Binding ◽  
Surface Adsorption ◽  
Metal Ligand

scholarly journals Protein-ligand binding interactions of imidazolium salts with SARS CoV-2

Heliyon ◽  
2020 ◽  
Vol 6 (11) ◽  
pp. e05544
Author(s):  
Dhurairaj Satheesh ◽  
Annamalai Rajendran ◽  
Kasi Chithra
Keyword(s):  
Ligand Binding ◽  
Imidazolium Salts ◽  
Binding Interactions

Characterization of the r-state insulin hexamer and its derivatives. The hexamer is stabilized by heterotropic ligand binding interactions

Biochemistry ◽  
1991 ◽  
Vol 30 (27) ◽  
pp. 6636-6645 ◽  
Author(s):  
Mark L. Brader ◽  
Niels C. Kaarsholm ◽  
Robert W. K. Lee ◽  
Michael F. Dunn
Keyword(s):  
Ligand Binding ◽  
Binding Interactions

scholarly journals Solvent manipulation of the pre-reduction metal–ligand complex and particle-ligand binding for controlled synthesis of Pd nanoparticles

Nanoscale ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 206-217
Author(s):  
Wenhui Li ◽  
Michael G. Taylor ◽  
Dylan Bayerl ◽  
Saeed Mozaffari ◽  
Mudit Dixit ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Growth Rates ◽  
Pd Nanoparticles ◽  
Nucleation And Growth ◽  
Controlled Synthesis ◽  
Ligand Complex ◽  
Metal Ligand

Understanding how to control the nucleation and growth rates is crucial for designing nanoparticles with specific sizes and shapes.

scholarly journals The interplay of electrostatic fields and binding interactions determining catalytic-site reactivity in actinidin. A possible origin of differences in the behaviour of actinidin and papain

1989 ◽  
Vol 259 (2) ◽  
pp. 443-452 ◽  
Author(s):  
D Kowlessur ◽  
M O'Driscoll ◽  
C M Topham ◽  
W Templeton ◽  
E W Thomas ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Ligand Binding ◽  
Transition State ◽  
Rate Constant ◽  
Ph Dependence ◽  
Order Rate Constant ◽  
Catalytic Site ◽  
Binding Interactions ◽  
Electrostatic Fields ◽  
Transition State Geometry

1. The pH-dependence of the second-order rate constant (k) for the reaction of actinidin (EC 3.4.22.14) with 2-(N'-acetyl-L-phenylalanylamino)ethyl 2'-pyridyl disulphide was determined and the contributions to k of various hydronic states were evaluated. 2. The data were used to assess the consequences for transition-state geometry of providing P2/S2 hydrophobic contacts in addition to hydrogen-bonding opportunities in the S1-S2 intersubsite region. 3. The P2/S2 contacts (a) substantially improve enzyme-ligand binding, (b) greatly enhance the contribution to reactivity of the hydronic state bounded by pKa 3 (the pKa characteristic of the formation of catalytic-site-S-/-ImH+ state) and pKa 5 (a relatively minor contributor in reactions that lack the P2/S2 contacts), such that the major rate optimum occurs at pH 4 instead of at pH 2.8-2.9, and (c) reveal the kinetic influence of a pKa approx. 6.3 not hitherto observed in reactions of actinidin. 4. Possibilities for the interplay of electrostatic effects and binding interactions in both actinidin and papain (EC 3.4.22.2) are discussed.

A General Mass Spectrometry-Based Assay for the Quantitation of Protein−Ligand Binding Interactions in Solution

2002 ◽  
Vol 124 (35) ◽  
pp. 10256-10257 ◽  
Author(s):  
Kendall D. Powell ◽  
Sina Ghaemmaghami ◽  
Michael Z. Wang ◽  
Liyuan Ma ◽  
Terrance G. Oas ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ligand Binding ◽  
Binding Interactions ◽  
General Mass
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