Scalable Solution-Phase Synthesis of the Biologically Active Cyclodepsipeptide Destruxin E, a Potent Negative Regulator of Osteoclast Morphology

2013 ◽  
Vol 79 (1) ◽  
pp. 296-306 ◽  
Author(s):  
Masahito Yoshida ◽  
Hiroshi Sato ◽  
Yoshitaka Ishida ◽  
Hiroshi Nakagawa ◽  
Takayuki Doi
Keyword(s):  
Biologically Active ◽  
Negative Regulator ◽  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis ◽  
Potent Negative Regulator

Synthetic and Biological Activity Studies on a New Cyclic Pentapeptide, Cyclonitroproctolin

2005 ◽  
Vol 60 (12) ◽  
pp. 1308-1312
Author(s):  
Boja Poojary ◽  
Shiddappa L. Belagali
Keyword(s):  
Biological Activity ◽  
Synthetic Peptide ◽  
Analytical Data ◽  
Biologically Active ◽  
Solution Phase ◽  
Pharmacological Activities ◽  
Phase Synthesis ◽  
Solution Phase Synthesis

The synthesis of a new biologically active cyclic pentapeptide, cyclonitroproctolin, cyclo(-Arg (NO2)-Tyr-Leu-Pro-Thr-) by solution phase synthesis is described. The structure of the synthetic peptide was characterized by IR, NMR, FAB mass and analytical data. The newly synthesized compound was screened for its antimicrobial and pharmacological activities.

Solution phase synthesis of oligonucleotides by the phosphoramidite method using solid supported reagents

2005 ◽  
Author(s):  
François Morvan ◽  
Aude-Emmanuelle Navarro ◽  
Cécile Dueymes ◽  
Ilaria Adamo ◽  
Andreas Schoenberger ◽  
...  
Keyword(s):  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis

Polymer-Assisted Parallel Solution Phase Synthesis of Substituted Benzimidazoles.

ChemInform ◽  
2010 ◽  
Vol 33 (35) ◽  
pp. 123-123
Author(s):  
Young K. Yun ◽  
John A. Porco Jr. ◽  
Jeff Labadie
Keyword(s):  
Solution Phase ◽  
Phase Synthesis ◽  
Parallel Solution ◽  
Solution Phase Synthesis

Solution-phase synthesis of monodispersed SnTe nanocrystallites at room temperature

2003 ◽  
Vol 6 (2) ◽  
pp. 181-184 ◽  
Author(s):  
Changhua An ◽  
Kaibin Tang ◽  
Bin Hai ◽  
Guozhen Shen ◽  
Chunrui Wang ◽  
...  
Keyword(s):  
Room Temperature ◽  
Solution Phase ◽  
Phase Synthesis ◽  
Solution Phase Synthesis
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