Palladium-Catalyzed Desulfitative Conjugate Addition of Aryl Sulfinic Acids and Direct ESI-MS for Mechanistic Studies

2012 ◽  
Vol 77 (10) ◽  
pp. 4849-4853 ◽  
Author(s):  
Huifeng Wang ◽  
Yaming Li ◽  
Rong Zhang ◽  
Kun Jin ◽  
Defeng Zhao ◽  
...  
Keyword(s):  
Conjugate Addition ◽  
Mechanistic Studies ◽  
Esi Ms ◽  
Sulfinic Acids ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Desulfitative Conjugate Addition of Aryl Sulfinic Acids and Direct ESI-MS for Mechanistic Studies.

ChemInform ◽  
2012 ◽  
Vol 43 (36) ◽  
pp. no-no
Author(s):  
Huifeng Wang ◽  
Yaming Li ◽  
Rong Zhang ◽  
Kun Jin ◽  
Defeng Zhao ◽  
...  
Keyword(s):  
Conjugate Addition ◽  
Mechanistic Studies ◽  
Esi Ms ◽  
Sulfinic Acids ◽  
Palladium Catalyzed

Chemoselective Aromatic Azido Reduction with Concomitant Aliphatic Azide Employing Al/Gd Triflates/NaI and ESI-MS Mechanistic Studies

2009 ◽  
Vol 15 (29) ◽  
pp. 7215-7224 ◽  
Author(s):  
Ahmed Kamal ◽  
Nagula Markandeya ◽  
Nagula Shankaraiah ◽  
C. Ratna Reddy ◽  
S. Prabhakar ◽  
...  
Keyword(s):  
Mechanistic Studies ◽  
Esi Ms

Stereochemical and Mechanistic Studies on Conjugate Addition of Organocuprates to Acyclic Enones and Enoates:  Simple Rule for Diastereofacial Selectivity

1998 ◽  
Vol 63 (13) ◽  
pp. 4449-4458 ◽  
Author(s):  
Keiko Yamamoto ◽  
Hiroshi Ogura ◽  
Jun-ichi Jukuta ◽  
Hiroko Inoue ◽  
Kazuhiro Hamada ◽  
...  
Keyword(s):  
Conjugate Addition ◽  
Simple Rule ◽  
Mechanistic Studies

scholarly journals A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

2017 ◽  
Vol 8 (4) ◽  
pp. 2841-2851 ◽  
Author(s):  
Yining Ji ◽  
Hongming Li ◽  
Alan M. Hyde ◽  
Qinghao Chen ◽  
Kevin M. Belyk ◽  
...  
Keyword(s):  
Rational Design ◽  
Catalyst Design ◽  
Mechanistic Studies ◽  
Catalyst Activation ◽  
Palladium Catalyzed ◽  
Catalyzed Reactions

Detailed mechanistic studies of a Pd-catalyzed asymmetric C–N coupling led to a rational design of a new series of bis-phosphine mono-oxides ligated Pd(ii) pre-catalysts that allow for reliable and complete catalyst activation.

scholarly journals Mechanistic Studies of the Palladium-Catalyzed Desulfinative Cross-Coupling of Aryl Bromides and (Hetero)Aryl Sulfinate Salts

2020 ◽  
Vol 142 (7) ◽  
pp. 3564-3576 ◽  
Author(s):  
Antoine de Gombert ◽  
Alasdair I. McKay ◽  
Christopher J. Davis ◽  
Katherine M. Wheelhouse ◽  
Michael C. Willis
Keyword(s):  
Cross Coupling ◽  
Mechanistic Studies ◽  
Aryl Bromides ◽  
Palladium Catalyzed

scholarly journals Palladium-catalyzed Suzuki-Miyaura coupling of thioureas or thioamides

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Shaoyu Mai ◽  
Wendong Li ◽  
Xue Li ◽  
Yingwei Zhao ◽  
Qiuling Song
Keyword(s):  
Silver Salt ◽  
Coupling Reaction ◽  
Coupling Reactions ◽  
Mechanistic Studies ◽  
Aromatic Rings ◽  
Cross Coupling Reactions ◽  
Broad Array ◽  
Palladium Catalyzed

AbstractCross-coupling reactions involving metal carbene intermediates play an increasingly important role in C–C bond formation. Expanding the carbene precursors to a broader range of starting materials and more diverse products is an ongoing challenge in synthetic organic chemistry. Herein, we report a Suzuki-Miyaura coupling reaction of in situ-generated Pd–carbene complexes via desulfurization of thioureas or thioamides. This strategy enables the preparation of a broad array of substituted amidinium salts and unsymmetrical diaryl ketones. The reaction is readily scalable, compatible with bromo groups on aromatic rings, tolerant to moisture and air and has a broad substrate scope. Furthermore, a single crystal structure of Pd-diaminocarbene complex is obtained and proven to be the key intermediate in both catalytic and stoichiometric reactions. Preliminary mechanistic studies demonstrate the dual role of the silver salt as a desulfurating reagent assisting the elimination of sulfur and as oxidant facilitating the PdII/Pd0/PdII catalytic cycle.

Multicomponent diversity-oriented synthesis of symmetrical and unsymmetrical 1,4-dihydropyridines in recyclable glycine nitrate (GlyNO3) ionic liquid: a mechanistic insight using Q-TOF, ESI-MS/MS

RSC Advances ◽  
2014 ◽  
Vol 4 (37) ◽  
pp. 19111-19121 ◽  
Author(s):  
Rajesh Kumar ◽  
Nitin H. Andhare ◽  
Amit Shard ◽  
Richa Richa ◽  
Arun Kumar Sinha
Keyword(s):  
Ionic Liquid ◽  
Mechanistic Studies ◽  
Diversity Oriented Synthesis ◽  
Esi Ms ◽  
Mechanistic Insight

Glycine nitrate (GlyNO3) ionic liquid has been explored for the synthesis of symmetrical and unsymmetrical 1,4-DHPs in good-to-excellent yields with mechanistic studies using Q-TOF and ESI-MS/MS.

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