A General Method for Palladium-Catalyzed Reactions of Primary Sulfonamides with Aryl Nonaflates

2011 ◽  
Vol 76 (11) ◽  
pp. 4552-4563 ◽  
Author(s):  
Shashank Shekhar ◽  
Travis B. Dunn ◽  
Brian J. Kotecki ◽  
Donna K. Montavon ◽  
Steven C. Cullen
Keyword(s):  
Palladium Catalyzed ◽  
Catalyzed Reactions ◽  
General Method

ChemInform Abstract: A General Method for Palladium-Catalyzed Reactions of Primary Sulfonamides with Aryl Nonaflates.

ChemInform ◽  
2011 ◽  
Vol 42 (38) ◽  
pp. no-no
Author(s):  
Shashank Shekhar ◽  
Travis B. Dunn ◽  
Brian J. Kotecki ◽  
Donna K. Montavon ◽  
Steven C. Cullen
Keyword(s):  
Palladium Catalyzed ◽  
Catalyzed Reactions ◽  
General Method

Sequential C-Selective Difluoromethylation/Pd-Catalyzed Decarboxylative Protonation: An Efficient Access to Tertiary Difluoromethylated Scaffolds

2019 ◽  
Author(s):  
Nicolas Duchemin ◽  
Roberto Buccafusca ◽  
Marc Daumas ◽  
Vincent Ferey ◽  
Stellios Arseniyadis
Keyword(s):  
Drug Development ◽  
Late Stage ◽  
Efficient Access ◽  
Palladium Catalyzed ◽  
General Method

We report here a general method that allows a highly straightforward access to tertiary difluoromethylated compounds. The strategy relies on a two-step sequence featuring a C-selective electrophilic difluoromethylation and an unprecedented palladium-catalyzed decarboxylative protonation. Considering the generality of the method and the attractive properties offered by the difluoromethyl group, this approach provides a valuable tool for late-stage functionalization and drug development.<br>

A General and Simple Removal of the Allyloxycarbonyl Protecting Group by Palladium-Catalyzed Reactions Using Nitrogen and Sulfur Nucleophiles

Synlett ◽  
1993 ◽  
Vol 1993 (09) ◽  
pp. 680-682 ◽  
Author(s):  
Jean Pierre Genêt ◽  
Errol Blart ◽  
Monique Savignac ◽  
Stéphane Lemeune ◽  
Sandrine Lemaire-Audoire ◽  
...  
Keyword(s):  
Protecting Group ◽  
Palladium Catalyzed ◽  
Catalyzed Reactions
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