Reactive Ketimino Radical Acceptors:  Intermolecular Alkyl Radical Addition to Imines with a Phenolic Hydroxyl Group

2006 ◽  
Vol 71 (5) ◽  
pp. 2099-2106 ◽  
Author(s):  
Hideto Miyabe ◽  
Yousuke Yamaoka ◽  
Yoshiji Takemoto
Keyword(s):  
Alkyl Radical ◽  
Radical Addition ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group

Aqueous Medium Radical Addition to Ketimines with a Phenolic Hydroxyl Group

Synlett ◽  
2004 ◽  
Vol 2004 (14) ◽  
pp. 2597-2599 ◽  
Author(s):  
Yoshiji Takemoto ◽  
Hideto Miyabe ◽  
Yousuke Yamaoka
Keyword(s):  
Aqueous Medium ◽  
Radical Addition ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group

Aqueous Medium Radical Addition to Ketimines with a Phenolic Hydroxyl Group.

ChemInform ◽  
2005 ◽  
Vol 36 (17) ◽  
Author(s):  
Hideto Miyabe ◽  
Yousuke Yamaoka ◽  
Yoshiji Takemoto
Keyword(s):  
Aqueous Medium ◽  
Radical Addition ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group

The Influence of Anthraquinone in Sulfite Delignification of Norway Spruce. 2. Phenolic Hydroxyl Group Formation

Holzforschung ◽  
1994 ◽  
Vol 48 (s1) ◽  
pp. 140-145 ◽  
Author(s):  
Hsin-Tai Chen ◽  
Masamitsu Funaoka ◽  
Yuan-Zong Lai
Keyword(s):  
Norway Spruce ◽  
Group Formation ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group

Methylation of Phenolic Hydroxyl Group and Demethylation of Anisoles

2009 ◽  
Vol 2009 (4) ◽  
pp. 229-230 ◽  
Author(s):  
Nobuhiro Sato ◽  
Hiroyuki Endo
Keyword(s):  
Microwave Heating ◽  
Room Temperature ◽  
Reverse Reaction ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group ◽  
Hydroxyl Groups ◽  
Phenolic Hydroxyl Groups ◽  
Phenyl Ethers ◽  
Methyl Phenyl

A mild methylation of phenolic hydroxyl groups with iodomethane was enabled in the presence of sodium bis(trimethylsilyl)amide at room temperature. The reverse reaction, namely demethylation of methyl phenyl ethers, was easily achieved by microwave heating with neat iodotrimethylsilane.

scholarly journals SYNTHESIS, IN VITRO ANTIOXIDANT AND ANTIMICROBIAL EVALUATION OF 3-HYDROXY CHROMONE DERIVATIVES

2018 ◽  
Vol 11 (3) ◽  
pp. 259
Author(s):  
Pallavi Kamble ◽  
Sailesh Wadher
Keyword(s):  
Antioxidant Activity ◽  
Double Bond ◽  
Antifungal Activity ◽  
Phenolic Hydroxyl ◽  
Hydroxyl Group ◽  
Antibacterial And Antifungal Activity ◽  
Activity Data ◽  
Group 4 ◽  
Antibacterial And Antifungal

 Objective: The objective of the present study was to synthesize a series of 3-hydroxychromone derivatives and to evaluate its in vitro antioxidant and antimicrobial activities.Methods: 3-hydroxy chromones were synthesized using an algar flynn oyamada method which includes oxidative cyclization of 2-hydroxy chalcones in basic solution by hydrogen peroxide. 2-hydroxy chalcones were synthesized by Claisen-Schmidt condensation of substituted 2-hydroxy acetophenones with substituted aromatic aldehydes using polyethylene glycol-400 as a recyclable solvent. The synthesized compounds were evaluated for in vitro antioxidant activity by 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay. In addition, these compounds were also screened for in vitro antibacterial and antifungal activity by agar cup method and Poison plate method, respectively.Results: The structures of the synthesized compounds were characterized by infrared, 1H nuclear magnetic resonance and mass spectroscopy. The antioxidant activity data revealed that all the synthesized derivatives exhibited good activity due to the presence of phenolic hydroxyl group, 4-oxo group and 2,3-double bond. Further, the activity increased with the introduction of a more phenolic hydroxyl group and adjacent methoxy group in the structure. The antimicrobial activity data showed that the compounds possess better antibacterial and antifungal activity which is attributed to the presence of phenolic hydroxyl group and 4-oxo group in the structure.Conclusions: The use of inexpensive, eco-friendly and readily available reagents, easy work-up and high purity of products makes the procedure a convenient and robust method for the synthesis of title compounds. The presence of phenolic hydroxyl group, 4-oxo group, and 2,3-double bond in the structure is responsible for their good antioxidant and antimicrobial activities.

Highly cis- and trans-selective alkyl radical addition to α-methylene-γ-phenyl-γ-butyrolactams

2009 ◽  
Vol 50 (12) ◽  
pp. 1301-1302 ◽  
Author(s):  
Tomoko Yajima ◽  
Masako Hamano ◽  
Hajime Nagano
Keyword(s):  
Alkyl Radical ◽  
Radical Addition ◽  
Cis And Trans
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