Four Orders of Magnitude Rate Increase in Artificial Enzyme-Catalyzed Aryl Glycoside Hydrolysis

2005 ◽  
Vol 70 (18) ◽  
pp. 7217-7226 ◽  
Author(s):  
Fernando Ortega-Caballero ◽  
Jeannette Bjerre ◽  
Line Skall Laustsen ◽  
Mikael Bols
Keyword(s):  
Rate Increase ◽  
Artificial Enzyme ◽  
Glycoside Hydrolysis ◽  
Aryl Glycoside

ROLE OF THE THYROID GLAND IN DEVELOPMENT AND MAINTENANCE OF RENAL HYPERTENSION IN RATS

1960 ◽  
Vol XXXIV (III) ◽  
pp. 411-429 ◽  
Author(s):  
Melvin J. Fregly ◽  
Kenneth M. Cook
Keyword(s):  
Blood Pressure ◽  
Rate Increase ◽  
Renal Hypertension ◽  
The Other ◽  
Elevated Blood Pressure ◽  
Unit Weight ◽  
Elevated Blood ◽  
Inhibition Of Growth ◽  
Testicular Size

ABSTRACT The anti-thyroid drugs, thiouracil, propylthiouracil, and methimazole, prevented both development of elevated blood pressure and cardiac hypertrophy usually accompanying kidney encapsulation with latex envelopes. These drugs also reduced elevated blood pressure of rats with hypertension of 13 to 40 weeks' duration prior to drug administration. Addition of desiccated thyroid powder to diet containing an anti-thyroid drug overcame the anti-hypertensive effect of the latter. Withdrawal of thyroid powder only was followed by return of blood pressure to previous low level within 3 weeks. The results suggest that the anti-hypertensive effect of these drugs is related directly to the hypothyroidism produced rather than to extrathyroidal effects of the drugs. Comparison of potencies of the 3 drugs in terms of anti-hypertensive effect, inhibition of growth rate, increase in testicular size, and increase in thyroid size suggests that propylthiouracil and methimazole are equally potent per unit weight of drug. Thiouracil has approximately half the potency of the other two.

Fe-N-C Artificial Enzyme: Activation of Oxygen for Dehydrogenation and Monoxygenation of Organic Substrates under Mild Condition and Cancer Therapeutic Application

2018 ◽  
Author(s):  
Fei He ◽  
Li Mi ◽  
Yanfei Shen ◽  
Toshiyuki Mori ◽  
Songqin Liu ◽  
...  
Keyword(s):  
Mild Condition ◽  
Enzyme Activation ◽  
Artificial Enzymes ◽  
Organic Substrates ◽  
Artificial Enzyme ◽  
Therapeutic Application ◽  
Highly Efficient ◽  
Activation Of Oxygen

Developing highly efficient artificial enzymes that directly employ O<sub>2</sub> as terminal oxidant has long been pursued but has rarely achieved yet. We report Fe-N-C has unusual enzyme-like activity in both dehydrogenation and monoxygenation of organic substrates with ~100% selectivity by direct using O<sub>2</sub>.

Inspecting Briquette Machine with Different Faults

2020 ◽  
Vol 13 ◽  
Author(s):  
Divesh Garg ◽  
Reena Garg ◽  
Vanita Garg
Keyword(s):  
Failure Rate ◽  
Rate Increase ◽  
Practical Importance ◽  
System Failure ◽  
Regenerative Point ◽  
Semi Markov Process ◽  
Major Fault ◽  
Environment Study ◽  
Burning Coal ◽  
Mean Time

Background: A briquette machine can be considered very useful in modern times as the need of energy consumption is increasing rapidly. Considering the harm to environment, study of briquette machine is the need of present times. In this paper, the operative unit is considered as briquette machine also known as bio-coal which is used for agroforestry waste. Objective: A single operative unit has been analyzed stochastically. The inspection of breakdown of a unit reveals the feasibility of the unit under the supervision of either ordinary or expert repairmen. Two types of fault are revealed by the repairmen either minor or major fault. Minor faults are repaired immediately by the same repairmen but whenever major fault held, the machine’s fault will be handled by expert person. Method: It is assumed that the repair needs no modification once served. Availability, Mean-time for system failure, and profits are analyzed by utilizing the Regenerative point graphical technique and semi-Markov process. Result: Study reveals that the Mean-time for system failure of the system model go on decreasing as failure rate increase and availability goes on decreasing as failure-rate increase. Moreover, the study shows that the systems profit goes down on increase of Failure-rate. Conclusion: Findings of the study supports the hypothesis that the limits of failure/repair/inspection rate will surely have effective profitability. Moreover, it is found that the utility of scale of operation can easily be derived. The practical importance of biomass briquettes for burning coal or wood is very well appreciated.

The Spending and Consumption Response to A VAT Rate Increase

2021 ◽  
pp. 000-000
Author(s):  
David Cashin ◽  
Takashi Unayama
Keyword(s):  
Rate Increase
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