Improving the Strategy and Performance of Molecularly Imprinted Polymers Using Cross-Linking Functional Monomers

2003 ◽  
Vol 68 (25) ◽  
pp. 9604-9611 ◽  
Author(s):  
Martha Sibrian-Vazquez ◽  
David A. Spivak
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Cross Linking ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
And Performance

Development of Improved Crosslinking Monomers for Molecularly Imprinted Materials

2002 ◽  
Vol 723 ◽  
Author(s):  
David A. Spivak ◽  
Martha Sibrian-Vazquez
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymers ◽  
Polymer Complex ◽  
Functional Monomer ◽  
Design Synthesis ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Catalytic Sites ◽  
And Performance

AbstractMolecular imprinting involves the self-assembled complexation of a substrate to functional monomers to form a pre-polymer complex which is “locked-in” to place by copolymerization with an excess of crosslinking monomer. Removal of the template leaves binding or catalytic sites that are complementary in size, shape, and functionality to the template. Most of the research in molecularly imprinted materials has focused on choice of substrate or functional monomer of the pre-polymer complex. The cross-linking monomers have primarily been EGDMA or DVB, which are commercially available. Redirecting focus on the design of crosslinking monomers for molecular imprinting, we have developed new classes of crosslinked polymers to optimize the performance of molecularly imprinted polymers. The design of the new crosslinking monomers has followed two strategies: (1) development of new crosslinked materials for formation of the supporting matrix, and (2) development of crosslinking monomers that simultaneously serve as the functional monomer. The details of the design, synthesis, polymerization and performance of these new crosslinking monomers for molecularly imprinted polymers will be reported.

scholarly journals Rational Design of Molecularly Imprinted Polymers Using Quaternary Ammonium Cations for Glyphosate Detection

Sensors ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 296
Author(s):  
Mashaalah Zarejousheghani ◽  
Alaa Jaafar ◽  
Hendrik Wollmerstaedt ◽  
Parvaneh Rahimi ◽  
Helko Borsdorf ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Quaternary Ammonium ◽  
Photoelectron Spectroscopy ◽  
Rational Design ◽  
Water Soluble ◽  
Trimethylammonium Chloride ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Quaternary Ammonium Cations

Molecularly imprinted polymers have emerged as cost-effective and rugged artificial selective sorbents for combination with different sensors. In this study, quaternary ammonium cations, as functional monomers, were systematically evaluated to design imprinted polymers for glyphosate as an important model compound for electrically charged and highly water-soluble chemical compounds. To this aim, a small pool of monomers were used including (3-acrylamidopropyl)trimethylammonium chloride, [2-(acryloyloxy)ethyl]trimethylammonium chloride, and diallyldimethylammonium chloride. The simultaneous interactions between three positively charged monomers and glyphosate were preliminary evaluated using statistical design of the experiment method. Afterwards, different polymers were synthesized at the gold surface of the quartz crystal microbalance sensor using optimized and not optimized glyphosate-monomers ratios. All synthesized polymers were characterized using atomic force microscopy, contact angle, Fourier-transform infrared, and X-ray photoelectron spectroscopy. Evaluated functional monomers showed promise as highly efficient functional monomers, when they are used together and at the optimized ratio, as predicted by the statistical method. Obtained results from the modified sensors were used to develop a simple model describing the binding characteristics at the surface of the different synthesized polymers. This model helps to develop new synthesis strategies for rational design of the highly selective imprinted polymers and to use as a sensing platform for water soluble and polar targets.

Water-compatible surface molecularly imprinted polymers with synergy of bi-functional monomers for enhanced selective adsorption of bisphenol A from aqueous solution

2016 ◽  
Vol 3 (1) ◽  
pp. 213-222 ◽  
Author(s):  
Feifei Duan ◽  
Chaoqiu Chen ◽  
Xiaofeng Zhao ◽  
Yongzhen Yang ◽  
Xuguang Liu ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Bisphenol A ◽  
Molecularly Imprinted Polymers ◽  
Selective Adsorption ◽  
Aqueous Media ◽  
Selective Removal ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Adsorption Performance

Water-compatible surface molecularly imprinted polymers were synthesized via bi-functional monomers and exhibited excellent adsorption performance for the selective removal of BPA from aqueous media.

scholarly journals Synthesis of Molecularly Imprinted Polymer via Emulsion Polymerization for Application in Solanesol Separation

2020 ◽  
Vol 10 (8) ◽  
pp. 2868 ◽  
Author(s):  
Guojie Zhao ◽  
Jing Liu ◽  
Minghong Liu ◽  
Xiaobin Han ◽  
Yulong Peng ◽  
...  
Keyword(s):  
Emulsion Polymerization ◽  
Molecularly Imprinted Polymers ◽  
Current Method ◽  
Synthesis Process ◽  
Cross Linking ◽  
Adsorption Effect ◽  
Synthesis Time ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Synthesis Conditions

High-purity solanesol can be used for pharmaceutical applications, but the current method for purifying solanesol has high cost and difficult continuous operation, and the use of molecular imprinting to purify natural products is a hot research topic of current research. Solanesol molecularly imprinted polymers were synthesized via emulsion polymerization for the first time. The morphology of the SSO-MIPs was observed with a scanning electron microscope, and the effects of the synthesis time, initiator dosage, functional monomer dosage, and cross-linking agent dosage on the adsorption effects under high-temperature and rapid synthesis conditions were discussed. The results demonstrate that the optimum synthesis conditions were a ratio of the template molecules to the functional monomers to the cross-linking agents of 1:8:30 (mol:mol:mol), 10 mg of the initiator, and a synthesis temperature of 70 °C. The imprinting factor of SSO-MIPs synthesized under the optimized process was found to reach 2.51, and the SSO-MIPs synthesized by this method exhibited a good adsorption effect, emitted less pollution during the synthesis process, and are convenient for demulsification. This research reports a reliable method for the synthesis of solanesol molecularly imprinted polymers.

Preparation and Performance Research on Glutathione Molecularly Imprinted Polymers

2011 ◽  
Vol 74 (5-6) ◽  
pp. 443-450 ◽  
Author(s):  
Yanjun Tong ◽  
Yu Xin ◽  
Hailin Yang ◽  
Ling Zhang ◽  
Yuran Zhang ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
And Performance ◽  
Performance Research

Novel β- Cyclodextrin Functional Monomers and its Application for Molecularly Imprinted Polymers

2015 ◽  
Vol 1101 ◽  
pp. 256-260 ◽  
Author(s):  
Feng Feng ◽  
Zhi Min Liu ◽  
Zhi Gang Xu
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Chemical Properties ◽  
Development Trend ◽  
The Novel ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Imprinted Polymers ◽  
Cavity Structure ◽  
Recognition Ability ◽  
Physical And Chemical

β-Cyclodextrin shows good molecular recognition ability for its unique physical and chemical properties and suitable cavity structure. The selective recognition can be further improved if β-cyclodextrin combines with molecularly imprinted technique. In this paper, the novel β-cyclodextrin functional monomers were introduced. And the preparation and application of molecularly imprinted polymers based on β-cyclodextrin functional monomers were reviewed. The development trend of β-cyclodextrin molecularly imprinted polymers were also prospected.

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