Facile One-Pot Coupling−Aminovinylation Approach to Push−Pull Chromophores:  Alkyne Activation by Sonogashira Coupling†

2003 ◽  
Vol 68 (4) ◽  
pp. 1503-1511 ◽  
Author(s):  
Alexei S. Karpov ◽  
Frank Rominger ◽  
Thomas J. J. Müller
Keyword(s):  
Sonogashira Coupling ◽  
One Pot

One-Pot Synthesis of Naphtho[1′,2′:4,5]imidazo[1,2-a ]pyridin-5-yl(aryl)methanones through Sequential Sonogashira Coupling/Alkyne-Carbonyl Metathesis

2017 ◽  
Vol 2017 (27) ◽  
pp. 4026-4034 ◽  
Author(s):  
Mirza Feroz Baig ◽  
Siddiq Pasha Shaik ◽  
Namballa Hari Krishna ◽  
Neeraj Kumar Chouhan ◽  
Abdullah Alarifi ◽  
...  
Keyword(s):  
Sonogashira Coupling ◽  
One Pot ◽  
One Pot Synthesis

ChemInform Abstract: An Efficient, General Synthesis of 2-Substituted 3,6-Dihydropyrrolo[3,2-e]indoles Involving One-Pot Sonogashira Coupling and Cyclization.

ChemInform ◽  
2013 ◽  
Vol 44 (32) ◽  
pp. no-no
Author(s):  
Moumita Rakshit ◽  
Taraknath Kundu ◽  
Gandhi K. Kar ◽  
Manas Chakrabarty
Keyword(s):  
Sonogashira Coupling ◽  
One Pot ◽  
General Synthesis

scholarly journals Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Xingjie Zhang ◽  
Di Qi ◽  
Chenchen Jiao ◽  
Xiaopan Liu ◽  
Guisheng Zhang
Keyword(s):  
Functional Group ◽  
High Efficiency ◽  
Materials Science ◽  
Alkylating Agents ◽  
Sonogashira Coupling ◽  
Pincer Ligand ◽  
One Pot ◽  
Mild Conditions ◽  
Alkyl Amines ◽  
Sonogashira Reactions

AbstractAlkynes are amongst the most valuable functional groups in organic chemistry and widely used in chemical biology, pharmacy, and materials science. However, the preparation of alkyl-substituted alkynes still remains elusive. Here, we show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts. Key to the success of this coupling is the development of an easily accessible and bench-stable amide-type pincer ligand. This ligand allows naturally abundant alkyl amines as alkylating agents in Sonogashira reactions, and produces diverse alkynes in excellent yields under mild conditions. Salient merits of this chemistry include broad substrate scope and functional group tolerance, gram-scale synthesis, one-pot transformation, versatile late-stage derivatizations as well as the use of inexpensive pre-catalyst and readily available substrates. The high efficiency and strong practicability bode well for the widespread applications of this strategy in constructing functional molecules, materials, and fine chemicals.

One-pot regioselective synthesis of substituted pyrazoles and isoxazoles in PEG-400/water medium by Cu-free nano-Pd catalyzed sequential acyl Sonogashira coupling–intramolecular cyclization

2019 ◽  
Vol 9 (22) ◽  
pp. 6471-6481 ◽  
Author(s):  
Narasimha Swamy Thirukovela ◽  
Ramesh Balaboina ◽  
Vinayak Botla ◽  
Ravinder Vadde ◽  
Sreekantha Babu Jonnalagadda ◽  
...  
Keyword(s):  
Intramolecular Cyclization ◽  
Pd Nanoparticles ◽  
Environmentally Benign ◽  
Water Medium ◽  
Sonogashira Coupling ◽  
One Pot ◽  
Peg 400 ◽  
Sequential Coupling ◽  
Substituted Pyrazoles

Catalyst efficacy of in situ generated Pd-nanoparticles in the regioselective one-pot synthesis of substituted pyrazoles and isoxazoles via sequential coupling-cyclization methodology in environmentally benign medium is described.

One-Pot Transformation of Me3Si-/Ph2P(O)-Protected Ethynes to Unsymmetrical Arylethynes

2018 ◽  
Vol 42 (5) ◽  
pp. 271-273 ◽  
Author(s):  
Li-fen Peng ◽  
Jia-ying Lei ◽  
Li Wu ◽  
Zi-long Tang ◽  
Zhi-peng Luo ◽  
...  
Keyword(s):  
High Yield ◽  
Sonogashira Coupling ◽  
One Pot ◽  
Mild Conditions ◽  
Phenylene Ethynylenes

Me3Si-/Ph2P(O)-protected ethynes were successfully transformed to unsymmetrical arylethynes via a one-pot Ph2P(O)-deprotection/ [Pd(dppf)Cl2]-catalysed coupling and one-pot Me3Si-deprotection/Sonogashira coupling under mild conditions and in high yield. Unsymmetrical phenylethynes, unsymmetrical extended phenylene ethynylenes and unsymmetrical anthrylethynes were successfully synthesised in good to excellent yields.

A one-pot synthesis of 2,2′-disubstituted diindolylmethanes (DIMs) via a sequential Sonogashira coupling and cycloisomerization/C3-functionalization of 2-iodoanilines

2017 ◽  
Vol 15 (33) ◽  
pp. 6997-7007 ◽  
Author(s):  
Anirban Kayet ◽  
Vinod K. Singh
Keyword(s):  
Sonogashira Coupling ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis

Pd(ii)–Ag(i) catalysed, highly efficient synthesis of diindolylmethanes under mild reaction conditions, with six new bonds being formed in a one-pot fashion, and the products being transformed into synthetically useful compounds.

Efficient one-pot synthesis of new 1-amino substituted pyrrolo[1,2-a]quinoline-4-carboxylate esters via copper-free Sonogashira coupling reactions

2016 ◽  
Vol 21 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Ali Keivanloo ◽  
Shaghayegh Sadat Kazemi ◽  
Hossein Nasr-Isfahani ◽  
Abdolhamid Bamoniri
Keyword(s):  
Coupling Reactions ◽  
Sonogashira Coupling ◽  
One Pot ◽  
One Pot Synthesis
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