Solid-Phase Synthesis of 4(1H)-Quinolone and Pyrimidine Derivatives Based on a New ScaffoldPolymer-Bound Cyclic Malonic Acid Ester

2002 ◽  
Vol 67 (19) ◽  
pp. 6731-6737 ◽  
Author(s):  
Xian Huang ◽  
Zhanxiang Liu
Keyword(s):  
Malonic Acid ◽  
Acid Ester ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Pyrimidine Derivatives ◽  
Phase Synthesis

Solid-Phase Synthesis and Inhibitory Effects of Some Pyrido[1,2-c]pyrimidine Derivatives on Leukocyte Functions and Experimental Inflammation

2001 ◽  
Vol 44 (6) ◽  
pp. 1011-1014 ◽  
Author(s):  
Pedro Molina ◽  
Enrique Aller ◽  
Ángeles Lorenzo ◽  
Pablo López-Cremades ◽  
Inmaculada Rioja ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Inhibitory Effects ◽  
Pyrimidine Derivatives ◽  
Phase Synthesis ◽  
Experimental Inflammation

scholarly journals Solid Phase Synthesis and Antimicrobial Activity of Novel Triazolo[1,5-a]pyrimidine Derivatives

2020 ◽  
Vol 32 (9) ◽  
pp. 2298-2302
Author(s):  
SHOBHANA A. GADARA ◽  
KARTIK D. LADVA
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Dilution Method ◽  
Pyrimidine Derivatives ◽  
Phase Synthesis ◽  
Inhibition Concentration ◽  
Broth Dilution

A new series of triazolo[4,3-a]pyimidine derivatives via solid phase multicomponent reaction between 3-oxo-N-(4-(3-oxomorpholino)- phenyl)butanamide, aromatic aldehyde and aminoazole is reported. All the synthesized compounds have been characterized by elemental analysis and spectral analyses. Moreover, the synthesized compounds were also screened for their antibacterial activity against Staphylococcus aureus MTCC-96, Escherichia coli MTCC-443, Bacillus subtilis MTCC-441, Pseudomonas aeruginosa MTCC 1688, and antifungal activity against Aspergillus niger MTCC-282 and Penicillium sp. at different concentration and compared with standards drugs. The minimum inhibition concentration (MIC) of the compounds was studied by micro-broth dilution method.

Microwave Assisted Solid Phase Synthesis of Pyrimidine Derivatives.

ChemInform ◽  
2003 ◽  
Vol 34 (10) ◽  
Author(s):  
Mazaahir Kidwai ◽  
Bhavesh Dave ◽  
R. Venkataramanan
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Pyrimidine Derivatives ◽  
Phase Synthesis ◽  
Microwave Assisted
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