A Novel [2 + 3] Cycloaddition Reaction:  Singlet Oxygen Mediated Formation of 1,3-Dipole from Iminodiacetic Acid Dimethyl Ester and Its Addition to Maleimides

2001 ◽  
Vol 66 (19) ◽  
pp. 6369-6374 ◽  
Author(s):  
Hao Cheng ◽  
Liangbing Gan ◽  
Yaru Shi ◽  
Xiaolan Wei
Keyword(s):  
Singlet Oxygen ◽  
Dimethyl Ester ◽  
Cycloaddition Reaction ◽  
Iminodiacetic Acid ◽  
Acid Dimethyl Ester

The synthesis and structure of a potential immunosuppressant: N-mycophenoyl malonic acid dimethyl ester

2018 ◽  
Vol 1151 ◽  
pp. 218-222 ◽  
Author(s):  
Agnieszka Siebert ◽  
Grzegorz Cholewiński ◽  
Dorota Garwolińska ◽  
Adrian Olejnik ◽  
Janusz Rachoń ◽  
...  
Keyword(s):  
Malonic Acid ◽  
Dimethyl Ester ◽  
Acid Dimethyl Ester

ChemInform Abstract: Regioselective Addition of Cyclic Nitrones to Feist′s Acid Dimethyl Ester.

ChemInform ◽  
2012 ◽  
Vol 43 (50) ◽  
pp. no-no
Author(s):  
A. P. Molchanov ◽  
T. Q. Tran ◽  
R. R. Kostikov
Keyword(s):  
Dimethyl Ester ◽  
Cyclic Nitrones ◽  
Acid Dimethyl Ester ◽  
Regioselective Addition

Phthalic acid, dimethyl ester

1998 ◽  
pp. 391-395
Author(s):  
Ben van Lierop ◽  
Laurence Castle ◽  
Alexandre Feigenbaum ◽  
Achim Boenke
Keyword(s):  
Phthalic Acid ◽  
Dimethyl Ester ◽  
Acid Dimethyl Ester

Flexible Entry into 3-Arylpent-2-enedioic Acids via Heck–Matsuda Arylation of Dimethyl Glutaconate with Arenediazonium Tosylates

Synthesis ◽  
2019 ◽  
Vol 51 (10) ◽  
pp. 2230-2236 ◽  
Author(s):  
Dmitry Dar’in ◽  
Grigory Kantin ◽  
Olga Bakulina ◽  
Raivis Žalubovskis ◽  
Mikhail Krasavin
Keyword(s):  
Dimethyl Ester ◽  
Thioredoxin Reductase ◽  
Acid Dimethyl Ester ◽  
Compound Libraries ◽  
Good Yielding ◽  
Glutaconic Acid ◽  
Michael Acceptors ◽  
Limited Scope

For the preparation of compound libraries of Michael acceptors with tunable reactivity toward nuclophilic selenocysteine residue of thioredoxin reductase, a range of 3-arylglutaconic acids were required. The existing methods at the time had limited scope or involved several steps. A hitherto undescribed protocol for direct palladium(II) acetate-catalyzed arylation of glutaconic acid dimethyl ester at position 3 has been developed with a diverse set of arenediazonium tosylates followed by hydrolysis. This generally good-yielding two-step sequence displayed a propensity to deliver E-configured coupling products while compounds mostly featured in the literature were predominantly Z-configured. The possibility for preparing a library of 4-arylpyridine-2,6(1H,3H)-diones has been exemplified.

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