THE KINETICS OF BASIC HYDROLYSIS OF SOME γ-LACTONES AND γ-THIOLACTONES IN AQUEOUS ACETONE1

1954 ◽  
Vol 19 (12) ◽  
pp. 1996-2003 ◽  
Author(s):  
CHARLES M. STEVENS ◽  
D. STANLEY TARBELL
Keyword(s):  
Basic Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of

The Kinetics of the Basic Hydrolysis of Difluoramine

1966 ◽  
Vol 88 (19) ◽  
pp. 4526-4528 ◽  
Author(s):  
Alan D. Craig ◽  
George A. Ward
Keyword(s):  
Basic Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of

Untersuchung der alkalischen Hydrolyse des Benzoesäurebenzylesters in Wasser-Äthanol 1 : 1 / Study of the Basic Hydrolysis of Benzyl Benzoate in Water-Ethyl Alcohol 1:1

1974 ◽  
Vol 29 (11) ◽  
pp. 1697-1698 ◽  
Author(s):  
F. Mansilla ◽  
P. Martinez ◽  
J. Sancho
Keyword(s):  
Experimental Data ◽  
Reaction Mechanism ◽  
Order Rate Constant ◽  
Benzyl Benzoate ◽  
Conductometric Method ◽  
Alcohol Medium ◽  
Basic Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of ◽  
Water Alcohol

By using a conductometric method, the kinetics of the basic hydrolysis of benzyl benzoate in water-alcohol medium has been investigated. The second order rate constant follows the equation K = A exp {-E/RT} with A = 1.35·1010 l mol-1 min-1 and E = 14.5 kcal mol-1. A reaction mechanism is postulated, which is consistent with the experimental data.

scholarly journals Solvent Effect on the Kinetics of the Basic Hydrolysis of Isatin.

1996 ◽  
Vol 44 (9) ◽  
pp. 1641-1646 ◽  
Author(s):  
Hamed M. ABU EL-NADER ◽  
Mahmoud N. H. MOUSSA
Keyword(s):  
Solvent Effect ◽  
Basic Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of

The basic hydrolysis of amino acid esters

1966 ◽  
Vol 19 (7) ◽  
pp. 1197 ◽  
Author(s):  
RW Hay ◽  
LJ Porter ◽  
PJ Morris
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Steric Effects ◽  
Ionization Constants ◽  
Amino Acid Esters ◽  
Kinetic Measurements ◽  
Basic Hydrolysis ◽  
Kinetics Of ◽  
Hydrolysis Of ◽  
Acid Esters

The kinetics of alkaline hydrolyses of nine amino acid esters by the process H,2NCHRCO2R'+OH- + H2NCHRCO2-+R'OH have been studied at 25� and an ionic strength of 0.1M in water over a range of pH. The acid ionization constants of the various amino acid esters have been determined, and these are roughly 2 pK units lower than those of the corresponding amino acids. The kinetic measurements are interpretable on the basis of electrostatic and steric effects.

A FACILE SYNTHESIS AND REACTIONS OF AMINO SELENOLO[2,3-b]PYRIDINE CARBOXYLATE

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed
Keyword(s):  
Biological Activity ◽  
Carbonyl Compounds ◽  
Mass Spectra ◽  
The Other ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
High Biological Activity ◽  
Basic Hydrolysis ◽  
Pyridine Carboxylate ◽  
Hydrolysis Of

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.

Sign in / Sign up

Export Citation Format

Share Document