Stereochemistry of alkylation of carboxylic acid salt and ester .alpha. anions derived from cyclic systems

1980 ◽  
Vol 45 (16) ◽  
pp. 3236-3245 ◽  
Author(s):  
A. Paul Krapcho ◽  
Edward A. Dundulis
Keyword(s):  
Carboxylic Acid ◽  
Acid Salt ◽  
Cyclic Systems ◽  
Carboxylic Acid Salt

The dimethyl formamide – acyl halide complex and its application to the synthesis of acyl azides

1967 ◽  
Vol 45 (11) ◽  
pp. 1247-1251 ◽  
Author(s):  
Donald E. Horning ◽  
Joseph M. Muchowski
Keyword(s):  
Carboxylic Acid ◽  
Acid Chloride ◽  
Direct Conversion ◽  
Dimethyl Formamide ◽  
Acid Salt ◽  
Acyl Halide ◽  
Acyl Azides ◽  
Selective Formation ◽  
Carboxylic Acid Salt ◽  
Acid Azide

A description of the conditions which favor the formation of the acid chloride – dimethyl formamide complex is given. The utility of the complex is illustrated by its application to the synthesis of acyl azides and, in particular, by the selective formation of 3-bromopropionyl azide from the corresponding acid chloride. The complex also results from a carboxylic acid salt and N,N-dimethyl chloroformiminium chloride, and thus provides an alternative method of effecting the direct conversion of a carboxylic acid into the corresponding acid azide.

scholarly journals Synthesis and Characterisation of Activated Carbon Obtained from Marula (Sclerocarya birrea) Nutshell

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Tafadzwa Mkungunugwa ◽  
Shepherd Manhokwe ◽  
Armistice Chawafambira ◽  
Munyaradzi Shumba
Keyword(s):  
Activated Carbon ◽  
Carboxylic Acid ◽  
Bulk Density ◽  
Total Carbon ◽  
Polluted Water ◽  
Acid Salt ◽  
High Carbon ◽  
Total Carbon Content ◽  
Aliphatic Carboxylic Acid ◽  
Carboxylic Acid Salt

Globally, a ninth of people use polluted water sources because an estimated 300–400 Mt of waste and 90% of sewage are discharged into water bodies from industries and developing countries, respectively. The utilisation of indigenous fruit pits in producing novel adsorbents will greatly benefit in wastewater treatment. In most underdeveloped countries, activated carbon (AC) is imported at a high cost. The study was aimed at synthesising and characterisation of AC obtained from Marula nutshell. Carbonization of organic matter from Marula nutshell was carried out at 200°C, 400°C, 500°C, and 600°C. Sulphuric (H2SO4) and phosphoric (H3PO4) acids were used as activating agents at concentrations of 20–60% ( v / v ). Physicochemical characteristics of the AC, such as bulk density, moisture, ash, pH, and iodine number, were analyzed using standard methods. Functional groups and total carbon content were determined using the FTIR spectroscopy and Nitrogen Carbon Sulphur (NCS) analyzer, respectively. The values of carbon yield and total carbon in activated samples with H2SO4 and H3PO4 were 32.2–93.2%, 26.9–95.8%, and 46–79%, 20.8–69.8%, respectively. The pH, ash, moisture, and bulk density of activated high carbon samples with H2SO4 ranged from 2.4–6.1, 0.65–3.49%, 1.3–8.4%, and 0.42–0.62 gcm−3, respectively. Activated high carbon samples with H3PO4 had 2.7–3.2, 11.3–29.8%, 4.7–14.6%, and 0.39–0.54 gcm−3 pH, ash, moisture, and bulk density, respectively. The synthesised AC samples with 40% H3PO4 at 500°C had the highest iodine value of 1075.7 mg/g. FTIR results showed the presence of aliphatic carboxylic acid salt, inorganic nitrate (NO3−), and phosphate groups in the synthesised AC and were not significantly different ( p < 0.05 ) from commercial AC. The untreated Marula nutshell had some aliphatic hydrocarbon (alkanes), inorganic phosphate ( PO 4 3 − ), aliphatic ester (–COO), and aliphatic carboxylic acid salt (–C(=O)O–) groups. A novel adsorbent, AC was produced from Marula nutshell with the potential to be used in water treatment.

Synthesis of l,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and homologous pyridine and azepine analogues thereof

1982 ◽  
Vol 60 (18) ◽  
pp. 2295-2312 ◽  
Author(s):  
Humberto Carpio ◽  
Edvige Galeazzi ◽  
Robert Greenhouse ◽  
Angel Guzmán ◽  
Esperanza Velarde ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Carboxylic Acid ◽  
Acid Derivative ◽  
Sodium Borohydride ◽  
Acid Ester ◽  
Keto Acid ◽  
Acid Salt ◽  
Keto Ester ◽  
Acetic Acid Esters ◽  
Acid Esters

Several syntheses of the previously unknown 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and various 5- and 6-substituted derivatives thereof have been devised. Some of these processes have been extended to the heretofore unreported 5,6,7,8-tetrahydropyrrolo[1,2-a]pyridine-8-carboxylic acid and 5,6,7,8-tetrahydro-9H-pyrrolo[1,2-a]azepine-9-carboxylic acid derivatives.Two new processes were developed for the conversion of pyrroles into the corresponding pyrrol-2-acetic acid esters. Both processes were based on the use of the readily available ethoxalylpyrrole derivatives as the starting material. One sequence involved saponification of the α-keto ester, followed by Wolff–Kishner reduction of the crude α-keto acid salt and subsequent esterification of the acetic acid derivative thus produced. The second synthesis commenced with reduction of the 2-ethoxalpyrrole with sodium borohydride to the α-hydroxy ester, which was further reduced to the acetic acid ester with an equimolar mixture of triphenylphosphine and triphenylphosphine diiodide.

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