Bacteriostats. IV.1ι-Amino Acid Amide Derivatives

1961 ◽  
Vol 26 (3) ◽  
pp. 857-860 ◽  
Author(s):  
D. L. GARMAISE ◽  
R. W. KAY ◽  
G. Y. PARIS ◽  
R. J. RANZ ◽  
R. GAUDRY ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Amino Acid Amide ◽  
Amide Derivatives

N-(Fluorenyl-9-methoxycarbonyl)amino Acid Amide Derivatives as a New Class of Anti-cancer Agents

2009 ◽  
pp. 465-466 ◽  
Author(s):  
Lajos Gera ◽  
Daniel C. Chan ◽  
Vitalija Simkeviciene ◽  
Paul A. Jr Bunn ◽  
John M. Stewart
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Amino Acid Amide ◽  
New Class ◽  
Amide Derivatives ◽  
Anti Cancer

Amino acid amide derivatives of 2-[3-(aminomethyl)-4H-1,2,4-triazol-4-yl]benzophenones, a novel class of annulated peptidoaminobenzophenones

1982 ◽  
Vol 25 (12) ◽  
pp. 1466-1473 ◽  
Author(s):  
Kentaro Hirai ◽  
Toshio Fujishita ◽  
Teruyuki Ishiba ◽  
Hirohiko Sugimoto ◽  
Shigeru Matsutani ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Amino Acid Amide ◽  
Amide Derivatives ◽  
Derivatives Of

scholarly journals Intramolecular rearrangement of α-amino acid amide derivatives of 2-aminobenzothiazoles

2014 ◽  
Vol 55 (30) ◽  
pp. 4193-4195 ◽  
Author(s):  
Jeffrey C. Pelletier ◽  
Venkata Velvadapu ◽  
Mark E. McDonnell ◽  
Jay E. Wrobel ◽  
Allen B. Reitz
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Intramolecular Rearrangement ◽  
Amino Acid Amide ◽  
Amide Derivatives ◽  
Derivatives Of

ChemInform Abstract: Intramolecular Rearrangement of α-Amino Acid Amide Derivatives of 2-Aminobenzothiazoles.

ChemInform ◽  
2014 ◽  
Vol 45 (52) ◽  
pp. no-no
Author(s):  
Jeffrey C. Pelletier ◽  
Venkata Velvadapu ◽  
Mark E. McDonnell ◽  
Jay E. Wrobel ◽  
Allen B. Reitz
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Intramolecular Rearrangement ◽  
Amino Acid Amide ◽  
Amide Derivatives ◽  
Derivatives Of

Aminocarbonylation of 4-Iodo-1H-imidazoles with an Amino Acid Amide Nucleophile: Synthesis of Constrained H-Phe-Phe-NH2 Analogues

2013 ◽  
Vol 78 (23) ◽  
pp. 12251-12256 ◽  
Author(s):  
Anna Skogh ◽  
Rebecca Fransson ◽  
Christian Sköld ◽  
Mats Larhed ◽  
Anja Sandström
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Amino Acid Amide

ChemInform Abstract: Modular Amino Acid Amide Chiral Ligands for Enantioselective Addition of Diethylzinc to Aromatic Aldehydes.

ChemInform ◽  
2011 ◽  
Vol 42 (41) ◽  
pp. no-no
Author(s):  
Shaohua Gou ◽  
Zhongbin Ye ◽  
Jing Chang ◽  
Guangjun Gou ◽  
Mingming Feng
Keyword(s):  
Amino Acid ◽  
Acid Amide ◽  
Aromatic Aldehydes ◽  
Chiral Ligands ◽  
Amino Acid Amide ◽  
Enantioselective Addition

scholarly journals Topography of nucleic acid helices in solutions. The interaction specificities of optically active amino acid derivatives

1970 ◽  
Vol 117 (2) ◽  
pp. 247-256 ◽  
Author(s):  
Edmond J. Gabbay ◽  
Roberta W. Kleinman
Keyword(s):  
Amino Acid ◽  
Dissociation Constants ◽  
Acid Amide ◽  
Ion Exchange Resin ◽  
Calf Thymus Dna ◽  
Random Coil ◽  
Amide Derivatives ◽  
Calf Thymus ◽  
Proline Derivatives ◽  
Polar Substituents

The synthesis and interactions of the d- and l-enantiomers of the amino acid amide derivatives [Formula: see text] (I) and lysyl dipeptides [Formula: see text] (II) with poly rI·poly rC, poly rA·poly rU and calf thymus DNA is reported. The following results were found. (1) The degree of stabilization of the helices as measured by the Tm (‘melting’ temperature) of the helix–coil transition was dependent on the nature of the amino acid. (2) For the poly rI·poly rC helix, the l-enantiomers of salts (I) and (II) stabilized more than the d-enantiomers. The same was true for calf thymus DNA in the presence of salts (II) and for poly rA·poly rU in the presence of salts (II) and the proline derivatives of salts (I). (3) As R increased in size and became more apolar, the amount of stabilization of the poly rI·poly rC helix in the presence of salts (I) decreased. On the other hand, the amount of stabilization increased with more polar substituents. An attempt was then made to determine whether the difference in stabilization of the double-stranded helices at the Tm in the presence of the l- and d-enantiomers of salts (I) is due to the interaction with the helix, the random coil or both. A new method was developed for determining the binding of small ions to polyions that involves a competition between an insoluble polystyrene ion-exchange resin and the soluble polyion for the counterion. Dissociation constants are obtained for the complexes of single- and double-stranded helices with the salts (I). The results are illuminating and indicate that with certain helices, i.e. poly rA·poly rU, the interactions of salts (I) with the single strands may not be ignored. It is concluded that the high optical specificity found in Nature, i.e. d-ribose in nucleic acids and l-amino acids in proteins, cannot be attributed solely to monomer–polymer interactions described by Gabbay (1968).

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