Synthesis of 2-substituted derivatives of 5-amino-1-.beta.-D-ribofuranosylimidazole-4-carboxamide. Ring opening reactions of 2-azapurine nucleosides

1974 ◽  
Vol 39 (25) ◽  
pp. 3651-3654 ◽  
Author(s):  
George A. Ivanovics ◽  
Robert J. Rousseau ◽  
Masajiro Kawana ◽  
Prem C. Srivastava ◽  
Roland K. Robins
Keyword(s):  
Ring Opening ◽  
Ring Opening Reactions ◽  
Derivatives Of

Ring-Opening Reactions of Iminosugar-Derived Aziridines: Application to the General Synthesis of α-1-C-Substituted Derivatives of Fagomine.

ChemInform ◽  
2003 ◽  
Vol 34 (43) ◽  
Author(s):  
Jean-Yves Goujon ◽  
David Gueyrard ◽  
Philippe Compain ◽  
Olivier R. Martin ◽  
Naoki Asano
Keyword(s):  
Ring Opening ◽  
Ring Opening Reactions ◽  
Derivatives Of ◽  
General Synthesis

Synthesis of trifluoromethyl γ-aminophosphonates by nucleophilic aziridine ring opening

2015 ◽  
Vol 13 (39) ◽  
pp. 10050-10059 ◽  
Author(s):  
T. Cytlak ◽  
M. Saweliew ◽  
M. Kubicki ◽  
H. Koroniak
Keyword(s):  
Ring Opening ◽  
Aziridine Ring ◽  
Ring Opening Reactions ◽  
Derivatives Of

The synthesis of phosphonated derivatives of trifluoromethyl aziridines by two methods and their application in ring opening reactions have been demonstrated.

ChemInform Abstract: Sucrochemistry. Part 38. Ring-Opening Reactions of Sucrose Epoxides: Synthesis of 4′-Derivatives of Sucrose.

ChemInform ◽  
1987 ◽  
Vol 18 (45) ◽  
Author(s):  
R. KHAN ◽  
M. R. JENNER ◽  
H. LINDSETH ◽  
K. S. MUFTI ◽  
G. PATEL
Keyword(s):  
Ring Opening ◽  
Ring Opening Reactions ◽  
Derivatives Of

Synthesis of Functional Derivatives of 7,8-Dicarba-nido-undecaborate Anion by Ring-Opening of Its Cyclic Oxonium Derivatives

2007 ◽  
Vol 72 (12) ◽  
pp. 1676-1688 ◽  
Author(s):  
Marina Yu. Stogniy ◽  
Ekaterina N. Abramova ◽  
Irina A. Lobanova ◽  
Igor B. Sivaev ◽  
Vikentii I. Bragin ◽  
...  
Keyword(s):  
Ring Opening ◽  
Mechanism Of Formation ◽  
New Approach ◽  
Functional Derivatives ◽  
Ring Opening Reactions ◽  
Oxonium Derivatives ◽  
Derivatives Of

A new approach to synthesis of functional derivatives of 7,8-dicarba-nido-undecaborate anion based on ring-opening of its cyclic oxonium derivatives [10-(CH2)4O-7,8-C2B9H11] and [10-O(CH2CH2)2O-7,8-C2B9H11] with various nucleophiles was developed. Both cyclic oxonium derivatives can be obtained as single isomers by reaction of the parent anion [7,8-C2B9H12]- with mercury(II) chloride in the corresponding solvents. Mechanism of formation of the cyclic oxonium derivatives of 7,8-dicarba-nido-undecaborate anion was proposed. A series of 7,8-dicarba-nido-undecaborate derivatives with terminal carboxylic and azide functions were prepared by the ring-opening reactions of the cyclic oxonium derivatives with substituted phenolate and azide ions, respectively.

N-Substituted Derivatives of 2-Phenylcyclopropylamines. Ring-opening Reactions of 2-Phenylcyclopropane Derivatives1

1962 ◽  
Vol 27 (3) ◽  
pp. 768-773 ◽  
Author(s):  
CARL KAISER ◽  
ALFRED BURGER ◽  
LUDWIG ZIRNGIBL ◽  
CHARLES S. DAVIS ◽  
CHARLES L. ZIRKLE
Keyword(s):  
Ring Opening ◽  
Ring Opening Reactions ◽  
Derivatives Of

Ring-opening reactions of sucrose epoxides: Synthesis of 4′-derivatives of sucrose

1987 ◽  
Vol 162 (2) ◽  
pp. 199-207 ◽  
Author(s):  
Riaz Khan ◽  
Michael R. Jenner ◽  
Harold Lindseth ◽  
Khizar S. Mufti ◽  
Gita Patel
Keyword(s):  
Ring Opening ◽  
Ring Opening Reactions ◽  
Derivatives Of

Azabenzenes (azines) — The nitrogen derivatives of benzene with one to six N atoms: Stability, homodesmotic stabilization energy, electron distribution, and magnetic ring current; a computational study

2004 ◽  
Vol 82 (1) ◽  
pp. 50-69 ◽  
Author(s):  
Jürgen Fabian ◽  
E Lewars
Keyword(s):  
Ring Opening ◽  
Electron Distribution ◽  
Computational Study ◽  
Open Chain ◽  
Isolation Techniques ◽  
Ring Opening Reactions ◽  
The Stability ◽  
Magnetic Ring ◽  
Derivatives Of ◽  
Ab Initio Dft

The twelve azabenzenes — the species formed by replacing CH groups of benzene by N — were examined computationally (with emphasis on the six contiguous-nitrogen species). MP2(fc)/6-31G*, B3LYP/6-31G*, CCSD(T)/6-31G*//MP2(fc)/6-31G*, and G3(MP2) calculations were used to probe kinetic and thermodynamic stabilities, homodesmotic ring-opening energies, electron distribution (bond orders and lengths, Bird index), and NICS values, primarily to discern where the transition occurs from reasonably stable to highly fragile species. Some azabenzenes with three and those with four or more nitrogens are thermodynamically unstable, but kinetic stabilities indicated that, with the possible exception of hexaazabenzene, all the azabenzenes should be isolable, although some with four nitrogens might decompose at room temperature, and pentaazabenzene would require matrix isolation techniques. Although homodesmotic ring-opening reactions showed an almost monotonic decrease in the stability of the cyclic relative to the open-chain species (in appropriate ring-opening reactions) on going from benzene to hexaazabenzene, bond-order variation and NICS suggested this may be because of increasing destabilization by nitrogen lone pairs rather than because of a decrease in electron delocalization (in aromaticity). Key words: azines, azabenzenes, pentazine, hexazine, ab initio, DFT, aromaticity.

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