Heterocyclic compounds. XV. C-Glycosyl nucleosides. V. Novel one-step asymmetric synthesis of C-nucleoside analogs

1974 ◽  
Vol 39 (10) ◽  
pp. 1374-1379 ◽  
Author(s):  
Haruo Ogura ◽  
Hiroshi Takahashi
Keyword(s):  
Asymmetric Synthesis ◽  
Heterocyclic Compounds ◽  
Nucleoside Analogs ◽  
One Step

Zeolite-catalyzed acylation of heterocyclic compounds — VI. One-step synthesis of 3-(benzofuran-2-carbonyl)pentane-2,4-dione from 2-acetylbenzofuran over HY-zeolite

Tetrahedron ◽  
1998 ◽  
Vol 54 (49) ◽  
pp. 14757-14766 ◽  
Author(s):  
F. Richard ◽  
H. Carreyre ◽  
J.M. Coustard ◽  
C. Bachmann ◽  
G. Perot
Keyword(s):  
Heterocyclic Compounds ◽  
Hy Zeolite ◽  
One Step

Synthesis of biologically active heterocyclic compounds from allenic and acetylenic nitriles and related compounds

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Marthe Carine Djuidje Fotsing ◽  
Dieudonné Njamen ◽  
Zacharias Tanee Fomum ◽  
Derek Tantoh Ndinteh
Keyword(s):  
Michael Addition ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Biologically Active ◽  
Polycyclic Compounds ◽  
One Step ◽  
Pharmaceutical Properties ◽  
Related Compounds ◽  
Acetylenic Acids ◽  
The Michael Addition

Abstract Cyclic and polycyclic compounds containing moieties such as imidazole, pyrazole, isoxazole, thiazoline, oxazine, indole, benzothiazole and benzoxazole benzimidazole are prized molecules because of the various pharmaceutical properties that they display. This led Prof. Landor and co-workers to engage in the synthesis of several of them such as alkylimidazolenes, oxazolines, thiazolines, pyrimidopyrimidines, pyridylpyrazoles, benzoxazines, quinolines, pyrimidobenzimidazoles and pyrimidobenzothiazolones. This review covers the synthesis of biologically active heterocyclic compounds by the Michael addition and the double Michael addition of various amines and diamines on allenic nitriles, acetylenic nitriles, hydroxyacetylenic nitriles, acetylenic acids and acetylenic aldehydes. The heterocycles were obtained in one step reaction and in most cases, did not give side products. A brief discussion on the biological activities of some heterocycles is also provided.

One-Step Homologation for the Catalytic Asymmetric Synthesis of Deoxypropionates

2016 ◽  
Vol 23 (1) ◽  
pp. 149-156 ◽  
Author(s):  
Shiqing Xu ◽  
Haijun Li ◽  
Masato Komiyama ◽  
Akimichi Oda ◽  
Ei-ichi Negishi
Keyword(s):  
Asymmetric Synthesis ◽  
Catalytic Asymmetric Synthesis ◽  
One Step ◽  
Catalytic Asymmetric

Glucose - and Allose-Derived Chiral Auxiliaries

2019 ◽  
Vol 800 ◽  
pp. 36-41
Author(s):  
Evija Rolava ◽  
Jevgeņija Lugiņina ◽  
Māris Turks
Keyword(s):  
Asymmetric Synthesis ◽  
Bioactive Compounds ◽  
Heterocyclic Compounds ◽  
Biologically Active ◽  
Important Class ◽  
Chiral Auxiliaries ◽  
Asymmetric Alkylation ◽  
Pharmaceutical Agents

Oxazolidinones are an important class of heterocyclic compounds that are used as chiral auxiliaries in asymmetric synthesis and as biologically active pharmaceutical agents. Moreover, carbohydrates are ideal scaffolds to generate libraries of bioactive compounds due the presence of defined configuration. We report here asymmetric alkylation studies on N-derivatized glucose-and allose-based spirooxazolidinones which do act as chiral auxiliaries.

scholarly journals Recent Applications of Carbon‐Nitrogen Lyases in Asymmetric Synthesis of Noncanonical Amino Acids and Heterocyclic Compounds

ChemBioChem ◽  
2020 ◽  
Vol 21 (19) ◽  
pp. 2733-2742 ◽  
Author(s):  
Jielin Zhang ◽  
Mohammad Z. Abidin ◽  
Thangavelu Saravanan ◽  
Gerrit J. Poelarends
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Heterocyclic Compounds ◽  
Noncanonical Amino Acids
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