An asymmetric synthesis of enantiomerically pure (S)-(+)-linalool (3,7-dimethyl-1,6-octadien-3-ol) and a formal synthesis of (R)-(-)-linalool

1986 ◽  
Vol 51 (13) ◽  
pp. 2599-2601 ◽  
Author(s):  
Masaki Ohwa ◽  
Tetsuo Kogure ◽  
Ernest L. Eliel
Keyword(s):  
Asymmetric Synthesis ◽  
Formal Synthesis ◽  
Enantiomerically Pure

Indium Bromide-catalyzed Unprecedented Hydrogenolysis: A Novel One-Pot Synthesis of Per-O-Acetylated β-carboxymethyl O and S-glycosides

2020 ◽  
Vol 24 (8) ◽  
pp. 900-908
Author(s):  
Ram Naresh Yadav ◽  
Amrendra K Singh ◽  
Bimal Banik
Keyword(s):  
Asymmetric Synthesis ◽  
Chiral Auxiliary ◽  
Bioactive Molecules ◽  
One Pot ◽  
Enantiomerically Pure ◽  
Stereoselective Glycosylation ◽  
One Pot Synthesis ◽  
Wide Range

Numerous O (oxa)- and S (thia)-glycosyl esters and their analogous glycosyl acids have been accomplished through stereoselective glycosylation of various peracetylated bromo sugar with benzyl glycolate using InBr3 as a glycosyl promotor followed by in situ hydrogenolysis of resulting glycosyl ester. A tandem glycosylating and hydrogenolytic activity of InBr3 has been successfully investigated in a one-pot procedure. The resulting synthetically valuable and virtually unexplored class of β-CMGL (glycosyl acids) could serve as an excellent potential chiral auxiliary in the asymmetric synthesis of a wide range of enantiomerically pure medicinally prevalent β-lactams and other bioactive molecules of diverse medicinal interest.

Asymmetric synthesis of enantiomerically pure 7-isopropenyl-4a-methyl-3-methyleneoctahydrochromen-2-ones

2007 ◽  
Vol 18 (22) ◽  
pp. 2712-2718 ◽  
Author(s):  
Henryk Krawczyk ◽  
Marcin Śliwiński ◽  
Jacek Kędzia ◽  
Jakub Wojciechowski ◽  
Wojciech M. Wolf
Keyword(s):  
Asymmetric Synthesis ◽  
Enantiomerically Pure
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