Diazoethenes: their attempted synthesis from aldehydes and aromatic ketones by way of the Horner-Emmons modification of the Wittig reaction. A facile synthesis of alkynes

1982 ◽  
Vol 47 (10) ◽  
pp. 1837-1845 ◽  
Author(s):  
J. C. Gilbert ◽  
U. Weerasooriya
Keyword(s):  
Wittig Reaction ◽  
Facile Synthesis ◽  
Aromatic Ketones

ChemInform Abstract: A Facile Synthesis of 2-Amino-3H-quinazolin-4-ones with Tandem Aza-Wittig Reaction.

ChemInform ◽  
2010 ◽  
Vol 31 (33) ◽  
pp. no-no
Author(s):  
Ming-Wu Ding ◽  
Gui-Ping Zeng ◽  
Tian-Jie Wu
Keyword(s):  
Wittig Reaction ◽  
Facile Synthesis

Strategic Exploitation of the Wittig Reaction: Facile Synthesis of Heteroaromatics and Multifunctional Olefins

Synlett ◽  
2018 ◽  
Vol 29 (20) ◽  
pp. 2608-2622 ◽  
Author(s):  
Wenwei Lin ◽  
Praneeth Karanam ◽  
Ganapuram Reddy
Keyword(s):  
Wittig Reaction ◽  
Coumarin Derivatives ◽  
Facile Synthesis ◽  
Diversity Oriented Synthesis ◽  
New Methods ◽  
Intramolecular Wittig Reaction ◽  
New Synthesis ◽  
Wide Range ◽  
Industrial Level ◽  
New Strategies

In this account, our group’s efforts towards exploring new substrates as precursors for the Wittig reaction have been discussed. Several new strategies developed by our group for the generation of requisite ylides for the Wittig reaction are highlighted. The idea behind the development of some chemoselective and diversity-oriented strategies are discussed in detail in a progressive manner. These strategies encompass a wide range of substrates that are employed for the synthesis of an array of heterocycles and multifunctional olefins and present a huge scope for their application on an industrial level.1 Introduction2 Development of New Methods to Effect Intramolecular Wittig Reaction3 Development of a Catalytic Wittig Reaction4 New Synthesis of Bis-Heteroarenes5 Direct β-Acylation of 2-Arylidene-1,3-indandiones6 Doubly Chemoselective Protocol for the Diversity-Oriented Synthesis of Coumarin Derivatives7 Conclusion

Phosphorus-Recycling Wittig Reaction: Design and Facile Synthesis of a Fluorous Phosphine and Its Reusable Process in the Wittig Reaction

2020 ◽  
Vol 85 (22) ◽  
pp. 14684-14696
Author(s):  
Yuki Yamamoto ◽  
Shin-ichi Kawaguchi ◽  
Misaki Nishimura ◽  
Yuki Sato ◽  
Yoshihisa Shimada ◽  
...  
Keyword(s):  
Wittig Reaction ◽  
Facile Synthesis ◽  
Phosphorus Recycling

New Facile Synthesis of Imidazo[2,1-b]-1,3,4-thiadiazol-5(6H)-ones via Aza-Wittig Reaction.

ChemInform ◽  
2004 ◽  
Vol 35 (37) ◽  
Author(s):  
Ming-Wu Ding ◽  
Bo-Qiao Fu ◽  
Lin Cheng
Keyword(s):  
Wittig Reaction ◽  
Facile Synthesis

A facile synthesis of stilbene-linked porphyrin dimers via the Wittig reaction

2006 ◽  
Vol 10 (08) ◽  
pp. 1017-1021 ◽  
Author(s):  
Xuliang Jiang ◽  
Jian Wu ◽  
Yuanyuan Lu
Keyword(s):  
Wittig Reaction ◽  
Emission Spectra ◽  
Free Base ◽  
Facile Synthesis ◽  
Absorption And Emission ◽  
Absorption And Emission Spectra ◽  
Wittig Reagent ◽  
Porphyrin Dimers

A facile synthesis of free-base and metalated stilbene-linked porphyrin dimers via the Wittig reaction is reported. 5-(4-chloromethylphenyl)-10,15,20-triphenyl porphyrin was prepared by direct chloromethylation of meso-tetraphenylporphyrin as the useful precursor for both the porphyrin-derived Wittig reagent and the monoformylporphyrin. It was found that the stilbene-linked porphyrin dimers were formed with a remarkable sterochemical preference in the cis-form. Their absorption and emission spectra were measured.

scholarly journals Synthetic routes to 1,3-divinyl cyclobutanes

1987 ◽  
Author(s):  
Σωτήριος Ιερόπουλος
Keyword(s):  
Metal Complexes ◽  
Good Yield ◽  
Room Temperature ◽  
Wittig Reaction ◽  
Organic Reactions ◽  
New Method ◽  
Cycloaddition Reactions ◽  
Facile Synthesis ◽  
Synthetic Routes ◽  
Ketone Ester

The chemistry of the cyclobutadiene metal complexes of the last decade is reviewed. Emphasis is given to the organic reactions involving the cyclobutadiene ligand. Dichoro, dimethyl, and diphenyl ketenes were used in [2+21-cycloaddition reactions with 1,3-dienes, which included 1-vinyl cyclohexene, 2-triethylsilylbuta-l,3-diene and 1- and 2- trimethylsilyloxybuta-1,3-dienes. Thecycloadditions were rarely found to be regiospecific and nearly always low yielding. The produced cyclobutanones were very often unstable. 2,2-Diphenyl-3-(1'-triethylsilyl-1'-ethenyl) cyclobutanone was prepared but it was found not to produce the expected 1,3-divinyl cyclobutan-l-ol when treated with vinylmagnesium bromide. 2,2-Dimethyl and 2,2-diphenyl-3-ethoxy cyclobutanones were prepared and their reactions with vinylmagnesium bromide and methyl lithium were investigated. Ethyl 4,4-diphenylbut-3-enoate was formed when 2,2-diphenyl-3-ethoxy cyclobutanone was treated with vinylmagnesium bromide. As well as the above ester, the same cyclobutanone gave 5,5-diphenylpent4-en-2-one when treated with methyl lithium. 2,2-Dimethyl3-ethoxy cyclobutanone gave the expected alcohols when reacted with the same two reagents. 1-(11-Phenyl-2'-propenyl)-2,2-dimethyl-3-vinyl cyclobutane was synthesised starting from a-pinene. The best route was found to involve the preparation of pinonic aldehyde by ozonolysis of q-pinene. The aldehyde was reduced to pinonic alcohol which was then converted to pinonic iodide by treatment with triphenylphosphine and iodine. The iodide was dehydrohalogenated by a new method, described in chapter six of the thesis, to givel-acetyl-2,2-dimethy1-3-vinyl cyclobutane. A subsequent Wittig reaction gave the desired divinyl cyclobutane. Finally, the development of a new methodology is described for the dehydrohalogenation of primary bromides and iodides. It involves a novel, facile synthesis of tetrakis(triphenylphosphine) nickel. The primary halide is mixed with 1,8-diazabicyclo[5.4.0lundec-7-ene and the mixture added to the low valent nickel reagent. The alkene was formed in good yield after twelve hours of stirring at room temperature under argon. The reaction was applied to a few halides and it was found to be compatible with alcohol, ketone, ester, and ether groups.

A Facile Synthesis of 2-Mino-3H-Quinazolin-4-Ones with Tandem Aza-Wittig Reaction

2000 ◽  
Vol 30 (9) ◽  
pp. 1599-1604 ◽  
Author(s):  
Ming-Wu Ding ◽  
Gui-Ping Zeng ◽  
Tian-Jie Wu
Keyword(s):  
Wittig Reaction ◽  
Facile Synthesis
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