Improved synthesis of .alpha.-D-ribofuranosides via stereoselective alkylation of a dibutylstannylene derivative for ready access to the 2-substituted 2-deoxyarabinofuranosides

1982 ◽  
Vol 47 (8) ◽  
pp. 1506-1509 ◽  
Author(s):  
Tsann Long Su ◽  
Robert S. Klein ◽  
Jack J. Fox
Keyword(s):  
Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 781
Author(s):  
Ernesto Enríquez-Palacios ◽  
Teresa Arbeloa ◽  
Jorge Bañuelos ◽  
Claudia I. Bautista-Hernández ◽  
José G. Becerra-González ◽  
...  

Herein we report on a straightforward access method for boron dipyrromethene dyes (BODIPYs)-coumarin hybrids linked through their respective 8- and 6- positions, with wide functionalization of the coumarin fragment, using salicylaldehyde as a versatile building block. The computationally-assisted photophysical study unveils broadband absorption upon proper functionalization of the coumarin, as well as the key role of the conformational freedom of the coumarin appended at the meso position of the BODIPY. Such free motion almost suppresses the fluorescence signal, but enables us to apply these dyads as molecular rotors to monitor the surrounding microviscosity.


Author(s):  
Guillaume Bousrez ◽  
Olivier Renier ◽  
Steven P. Kelley ◽  
Brando Adranno ◽  
Elnaz Tahavori ◽  
...  

2014 ◽  
Vol 19 (4) ◽  
pp. 550-557 ◽  
Author(s):  
Ellen M Henderson ◽  
Margaret Fletcher

Evidence-based practice (EBP) is challenging for most nurses due to the time constraints of caring for patients and the emerging pressures of a changing health service. To explore these challenges, and thus to establish possible means of overcoming them, three focus groups ( n = 17) with children’s nurses were conducted. Participants were asked how they would define EBP, what the barriers to EBP were, what skills they needed to help access evidence and how they could integrate evidence into everyday practice. Data were analysed thematically and the anticipated themes of definitions of EBP, barriers, education and nursing culture were determined. Important subthemes were personal and employer disengagement, passivity and lack of resource utilisation. Passive use of evidence readily available in patient folders and on the wards was common. It seemed that little consideration was given to how often this evidence was updated. Nurses define their access to evidence as primarily passive in nature. This is reinforced by a lack of ready access to ongoing education and a perceived lack of investment at institutional level in their continued engagement with evidence. Promoting EBP needs to engage more with those ritual and traditional aspects of nursing culture to challenge these perceptions.


1995 ◽  
Vol 45 (1) ◽  
pp. 191-199 ◽  
Author(s):  
J. S. C. Eidinow
Keyword(s):  

Horace addresses Torquatus again in Carm. 4.7. There the poet distinguishes three cardinal qualities: Torquatus's genus, his facundia, and hispietas. Since Horace distinguishes them they were no doubt qualities on which Torquatus prided himself, but they are, in any case, the key by which Torquatus slips into Horace's lyric. I suggest that we can use the same key to open up the Epistle, and that by taking up these qualities we have ready access to the wit of the poem, carefully predicated upon its addressee.


2006 ◽  
Vol 90 (518) ◽  
pp. 209-214 ◽  
Author(s):  
Roger Voles

Family history research has become a very popular hobby during the last few years due to the ready access to records of births and marriages. Many people have rigorously traced their ancestors back to 1700 and earlier, corresponding to some 12 generations. The principal motivation of most amateur genealogists is to learn about the lives of their forebears and they trust these ‘legal’ records without question and do not usually acknowledge that cuckoldry may have occurred and that their true ancestors may not have been the ones recorded.


2018 ◽  
Vol 17 (1) ◽  
pp. 233-238
Author(s):  
TODD SHEPARD

The footprint of Dagmar Herzog's scholarship has moved from Germany to the United States, then back again, before expanding outwards across Europe as well as to spaces drawn into Europe's orbit by conquest. Historically specific intersections between gender, religion, and politics are her specialty, with sexuality and sex as crucial sightlines in the constantly shifting landscapes that these always-moving parts compose. No historian currently writing in English on the late modern period, arguably, more acutely captures the intensity and conflicts that absorb individuals as well as larger groups as they live in and through these distinct topographies. This she does, in part, through the depth and the breadth of her research, which allow Herzog to reveal connections and disjunctures in ways that grab the reader's attention as well as explain the stakes. Her writings reveal an ability to listen to sources and care about what they intimate that is more often seen in certain scholars of the medieval or other exotic histories that rely on scarce or sketchy sources. For historians of the modern era, between the birth of ideology and ready access to endless and dense types of documentation, what Herzog continues to do is a revelation.


2021 ◽  
Author(s):  
Benedetta Palucci ◽  
Giorgia Zanchin ◽  
Giovanni Ricci ◽  
Laure Vendier ◽  
Christian Lorber ◽  
...  
Keyword(s):  

2020 ◽  
pp. 69-77
Author(s):  
Yolande Berton-Ofouémé

This chapter highlights the results of a baseline survey conducted in Brazzaville in 1992-1993 and a follow-up survey in 2018 on changes in food consumption patterns based on meal monitoring and interviews with food consumers, caterers and food processing companies. Trends regarding meals created by city dwellers, meals from other African cities disseminated by immigrants and by the catering industry are also analysed. Urban catering has undergone major changes over the past 25 years, and Congolese city dwellers now have ready access to international meals as well as new locally invented dishes.


2021 ◽  
pp. 237-272
Author(s):  
Jon D. Wisman

The transition in Europe from a predominantly agricultural society dominated by a landed aristocracy to an emerging commercial one with an expanding bourgeoisie gave birth to a reformulated expression of Christianity whose doctrines could better legitimate the new institutions and practices of commercial society. Whereas Catholicism provided an ideology that justified the landlords’ capture of economic surplus, Protestantism legitimated the emerging bourgeoisie’s ability to do the same. Protestantism’s privileging of work and asceticism afforded social respectability to the bourgeoisie and ideological support for its capturing a share of society’s surplus. It gave legitimacy to the harsh social treatment of a rising class of wage workers who had been separated from any ownership, control, or ready access to the means of production. Protestantism served as a transitional religion between a traditional agricultural world dominated by Catholic doctrine and a more modern commercial one dominated by secular thought.


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