Stereoselective reduction of diketones by a novel carbonyl reductase from Candida parapsilosis

1990 ◽  
Vol 55 (14) ◽  
pp. 4377-4380 ◽  
Author(s):  
Hiroyuki Hata ◽  
Sakayu Shimizu ◽  
Shizuo Hattori ◽  
Hideaki Yamada
Keyword(s):  
Candida Parapsilosis ◽  
Carbonyl Reductase ◽  
Stereoselective Reduction

New insights into the stereospecific reduction by an (S) specific carbonyl reductase from Candida parapsilosis ATCC 7330: experimental and QM/MM studies

2020 ◽  
Vol 10 (17) ◽  
pp. 5925-5934 ◽  
Author(s):  
Sneha Sudhakara ◽  
Chandrasekaran Ramakrishnan ◽  
M. Michael Gromiha ◽  
Anju Chadha
Keyword(s):  
Quantum Mechanics ◽  
Molecular Mechanics ◽  
Reaction Mechanisms ◽  
Candida Parapsilosis ◽  
Carbonyl Reductase ◽  
Stereospecific Reduction ◽  
Candida Parapsilosis Atcc 7330 ◽  
Reduction Of Ketones

The quantum mechanics/molecular mechanics study of an (S) specific carbonyl reductase from C. parapsilosis ATCC 7330 showing a dual kinetic response for the reduction of ketones and α-ketoesters suggests different reaction mechanisms for the same.

Who's Who? Allocation of Carbonyl Reductase Isoenzymes from Candida parapsilosis by Combining Bio- and Computational Chemistry

ChemBioChem ◽  
2012 ◽  
Vol 13 (6) ◽  
pp. 803-809 ◽  
Author(s):  
Andre Jakoblinnert ◽  
Marco Bocola ◽  
Monideepa Bhattacharjee ◽  
Sonja Steinsiek ◽  
Mara Bönitz-Dulat ◽  
...  
Keyword(s):  
Computational Chemistry ◽  
Candida Parapsilosis ◽  
Carbonyl Reductase

Stereoselective reduction of 4-benzoylpyridine by recombinant pig heart carbonyl reductase

2003 ◽  
Vol 23 (1) ◽  
pp. 29-35 ◽  
Author(s):  
Hideaki Shimada ◽  
Sumie Fujiki ◽  
Michiko Oginuma ◽  
Makio Asakawa ◽  
Tadashi Okawara ◽  
...  
Keyword(s):  
Carbonyl Reductase ◽  
Stereoselective Reduction

A carbonyl reductase from Candida parapsilosis ATCC 7330: substrate selectivity and enantiospecificity

2017 ◽  
Vol 15 (19) ◽  
pp. 4165-4171 ◽  
Author(s):  
Sneha Sudhakara ◽  
Anju Chadha
Keyword(s):  
Potential Application ◽  
Candida Parapsilosis ◽  
Carbonyl Reductase ◽  
Substrate Selectivity ◽  
Chiral Molecules ◽  
Candida Parapsilosis Atcc 7330

A purified carbonyl reductase (SRED) asymmetrically reduces ketones and α-ketoesters to (S)-alcohols with a potential application in the synthesis of industrially important chiral molecules.

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