Regioselectivity in the alkylation of ambident anions of 1-acyl-1,2-dihydroquinaldonitriles (quinoline Reissert compounds)

1990 ◽  
Vol 55 (13) ◽  
pp. 4226-4229 ◽  
Author(s):  
Harry W. Gibson ◽  
Bardia Guilani
1981 ◽  
Vol 34 (1) ◽  
pp. 151 ◽  
Author(s):  
TV Hung ◽  
BA Mooney ◽  
RH Prager ◽  
AD Ward

The reactions of isoquinoline and phthalazine Reissert compounds with phthalaldehydic acids and their derivatives have been investigated as a means of synthesizing 1-(3-phthalidyl)isoquinolines. Of a variety of conditions tried those involving phase transfer were found, in general, to be the most suitable. The products, which are analogues of the convulsant alkaloid bicuculline, showed weak central nervous system depressant activity.


ChemInform ◽  
2011 ◽  
Vol 42 (10) ◽  
pp. no-no
Author(s):  
Sung Hwan Kim ◽  
Yu Mi Kim ◽  
Bo Ram Park ◽  
Jae Nyoung Kim
Keyword(s):  

Tetrahedron ◽  
2012 ◽  
Vol 68 (38) ◽  
pp. 8052-8067 ◽  
Author(s):  
Harry W. Gibson ◽  
Michael A.G. Berg ◽  
Terry L. Price ◽  
Zhenbin Niu ◽  
Minjae Lee ◽  
...  

1983 ◽  
pp. 235-261
Author(s):  
O. A. Reutov ◽  
I. P. Beletskaya ◽  
A. L. Kurts

1981 ◽  
Vol 12 (49) ◽  
Author(s):  
S. VEERARAGHAVAN ◽  
D. BHATTACHARJEE ◽  
F. D. POPP
Keyword(s):  

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