Synthetic methods and reactions. 144. Regiospecific and chemoselective ring opening of epoxides with trimethylsilyl cyanide-potassium cyanide/18-crown-6 complex

1990 ◽  
Vol 55 (7) ◽  
pp. 2016-2018 ◽  
Author(s):  
Mark B. Sassaman ◽  
G. K. Surya Prakash ◽  
George A. Olah
Keyword(s):  
Ring Opening ◽  
Potassium Cyanide ◽  
Synthetic Methods ◽  
Trimethylsilyl Cyanide ◽  
Ring Opening Of Epoxides

Metal(II) Schiff base complexes as catalysts for the high-regioselective conversion of epoxides to β-hydroxy nitriles in glycol solvents

2006 ◽  
Vol 84 (11) ◽  
pp. 1575-1579 ◽  
Author(s):  
Hossein Naeimi ◽  
Mohsen Moradian
Keyword(s):  
Schiff Base ◽  
Ring Opening ◽  
Potassium Cyanide ◽  
Biologically Active ◽  
Schiff Base Complexes ◽  
Mild Conditions ◽  
Ring Opening Of Epoxides ◽  
Facile Preparation ◽  
High Yields

A facile preparation of 3-hydroxy propanenitrile derivatives is described involving ring opening of epoxides with potassium cyanide in glycol solvents in the presence of Schiff base complexes as catalysts. This method occurs under neutral and mild conditions with high yields and high regioselectivity. Thus, several β-Hydroxy nitriles, useful intermediates toward biologically-active molecules, are easily obtained at room temperature.Key words: β-hydroxy nitrile, Schiff base, epoxide, glycol, catalyst.

scholarly journals Environmentally benign and highly regioselective ring opening of epoxides accelerated by ultrasound irradiation

2016 ◽  
Vol 9 (1) ◽  
pp. 76-84 ◽  
Author(s):  
Mohamed Mahmoud Nasef ◽  
Masoumeh Zakeri ◽  
Jahanbakhsh Asadi ◽  
Ebrahim Abouzari-Lotf ◽  
Arshad Ahmad ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ultrasound Irradiation ◽  
Environmentally Benign ◽  
Ring Opening Of Epoxides

ChemInform Abstract: RING OPENING OF CYCLOHEXENE EPOXIDE WITH TRIMETHYLSILYL CYANIDE

1983 ◽  
Vol 14 (24) ◽  
Author(s):  
G. O. SPESSARD ◽  
A. R. RITTER ◽  
D. M. JOHNSON ◽  
A. M. MONTGOMERY
Keyword(s):  
Ring Opening ◽  
Trimethylsilyl Cyanide

Regioselective Ring Opening of Epoxides with [Fe(BTC)]

Synfacts ◽  
2010 ◽  
Vol 2010 (10) ◽  
pp. 1208-1208
Author(s):  
H. Garcia ◽  
A. Dhakshinamoorthy ◽  
M. Alvaro
Keyword(s):  
Ring Opening ◽  
Ring Opening Of Epoxides
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