A short route to 2,3-dimethylene-7-oxabenzonorbornenes

1989 ◽  
Vol 54 (7) ◽  
pp. 1762-1764 ◽  
Author(s):  
Jihmei Luo ◽  
Harold Hart
Keyword(s):  
Short Route

Short Protecting Group-free Syntheses of CDE Synthon of Racemic Camptothecin

2020 ◽  
Vol 17 (7) ◽  
pp. 588-591
Author(s):  
Pingxuan Shao ◽  
Wei Lu ◽  
Lei Wang
Keyword(s):  
Total Synthesis ◽  
Future Development ◽  
Protecting Group ◽  
Short Route ◽  
The Future ◽  
Tricyclic Ketone

A practical and concise total synthesis of tricyclic ketone 7 (CDE ring), a valuable intermediate for the synthesis of racemic camptothecin and analogs, was described (8 chemical steps and 29% overall yield). The synthesis starts with two inexpensive, readily available materials and is operationally simple to perform. It is worth mentioning that the reported protecting group-free synthesis, with advantages of a short route, would be helpful for the future development of industry-scale syntheses of camptothecin-family alkaloids.

ChemInform Abstract: [4 + 2] Cycloaddition of α,β-Unsaturated Acid Anhydrides to 2-Furylpiperidin-4-ones: The Short Route to Annulated 8,10a-Epoxypyrido[2,1-a]isoindoles.

ChemInform ◽  
2010 ◽  
Vol 41 (35) ◽  
pp. no-no
Author(s):  
Fedor I. Zubkov ◽  
Inga K. Airiyan ◽  
Anastasiya A. Dzyubenko ◽  
Nataliya I. Yudina ◽  
Vladimir P. Zaytsev ◽  
...  
Keyword(s):  
Unsaturated Acid ◽  
Short Route ◽  
Acid Anhydrides

ChemInform Abstract: Superacidic Cyclization-Lipase-Mediated Kinetic Resolution as a Short Route from Achiral Linear Isoprenoid Alcohols to Scalemic Cyclic Isomers.

ChemInform ◽  
2010 ◽  
Vol 33 (38) ◽  
pp. no-no
Author(s):  
Edward P. Serebryakov ◽  
Galina D. Gamalevich ◽  
Veacheslav N. Kulcitki ◽  
Nicon D. Ungur ◽  
Pavel F. Vlad
Keyword(s):  
Kinetic Resolution ◽  
Short Route

ChemInform Abstract: Total Synthesis of Bryostatin 1: A Short Route

ChemInform ◽  
2012 ◽  
Vol 43 (5) ◽  
pp. no-no
Author(s):  
Soraya Manaviazar ◽  
Karl J. Hale
Keyword(s):  
Total Synthesis ◽  
Bryostatin 1 ◽  
Short Route

ChemInform Abstract: A Short Route to Malto-trisaccharide Synthons: Synthesis of the Branched Nonasaccharide, 6′′-α-Maltotriosyl-maltohexaose.

ChemInform ◽  
2010 ◽  
Vol 33 (22) ◽  
pp. no-no
Author(s):  
Iben Damager ◽  
Carl Erik Olsen ◽  
Birger Lindberg Moeller ◽  
Mohammed Saddik Motawia
Keyword(s):  
Short Route

A Short Route to the 8,13-Dioxo-14-methoxyberbines

Heterocycles ◽  
1980 ◽  
Vol 14 (6) ◽  
pp. 827 ◽  
Author(s):  
Maurice Shamma ◽  
G. Manikumar ◽  
M. Shamma
Keyword(s):  
Short Route

Reductive Condensation of a Nitro Group with Carboxylic Acids Promoted by Phosphorus(III) Compounds: A Short Route to 5H-Dibenzo[b,e][1,4]diazepin-11(10H)-ones

Synthesis ◽  
2020 ◽  
Author(s):  
Zbigniew Wróbel ◽  
Michał Tryniszewski ◽  
Robert Bujok ◽  
Roman Gańczarczyk
Keyword(s):  
Nitro Group ◽  
Carboxylic Acids ◽  
Carboxyl Group ◽  
Short Route ◽  
Step Method ◽  
One Pot ◽  
Aryl Group ◽  
Intramolecular Condensation ◽  
Reductive Condensation

Tributyl- or triphenylphosphine promotes a one-pot, three-step method for the synthesis of differently substituted dibenzodiazepinones from N-aryl-2-nitroanilines. Pyridine analogues and the corresponding thiazepinones can also be formed using this method. The process involves deoxygenation of the nitro group, then formation of an iminophosphorane intermediate and its intramolecular condensation with a carboxyl group placed in the N-aryl group. The role of the carboxyl group in the formation of the iminophosphorane and the mode of cyclization are discussed.

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