Use of biological systems for the synthesis of chiral molecules. 5. Microbiological reduction of acyclic .beta.-diketones

1988 ◽  
Vol 53 (22) ◽  
pp. 5215-5219 ◽  
Author(s):  
Annie Fauve ◽  
Henri Veschambre
2021 ◽  
Vol 2 (3) ◽  
pp. 25-32
Author(s):  
Valeria Loscr� ◽  
Anna Maria Vegni

With the advancement of nanotechnology, there has been fervid research activity on new communication paradigms suitable for new challenging contexts, such as biological systems. Among different approaches, the most considered has been artificial Molecular Communication, where entities such as synthetic molecules, enzymes, hormones, bacteria etc. are functionalized in order to implement information exchange with the surrounding system and with other entities. In this context, it is interesting to analyze specific features that could be exploited for effective communication paradigms. In this paper, we focus on chiral molecules (a.k.a. enantiomers) as novel enablers for a molecular communication paradigm. Chirality is an interesting and appealing feature existing in nature and that can be replicated with strong emphasis in new types of materials, such as metasurfaces and metamaterials. A deep knowledge of chirality features and how chiral molecules interact with each other or with achiral molecules provides insights into designing a new molecular communication technique suitable for biological environments. In this contribution, we will highlight the main applications of chiral molecules and we will present chiral features as the viable way for realizing a nanocommunication system.


1987 ◽  
Vol 52 (2) ◽  
pp. 256-260 ◽  
Author(s):  
Andre Belan ◽  
Jean Bolte ◽  
Annie Fauve ◽  
Jean G. Gourcy ◽  
Henri Veschambre

Author(s):  
Henry S. Slayter

Electron microscopic methods have been applied increasingly during the past fifteen years, to problems in structural molecular biology. Used in conjunction with physical chemical methods and/or Fourier methods of analysis, they constitute powerful tools for determining sizes, shapes and modes of aggregation of biopolymers with molecular weights greater than 50, 000. However, the application of the e.m. to the determination of very fine structure approaching the limit of instrumental resolving power in biological systems has not been productive, due to various difficulties such as the destructive effects of dehydration, damage to the specimen by the electron beam, and lack of adequate and specific contrast. One of the most satisfactory methods for contrasting individual macromolecules involves the deposition of heavy metal vapor upon the specimen. We have investigated this process, and present here what we believe to be the more important considerations for optimizing it. Results of the application of these methods to several biological systems including muscle proteins, fibrinogen, ribosomes and chromatin will be discussed.


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