Synthetic studies on pyrrolizidine alkaloid antitumor agents. Enantioselective synthesis of retronecine and its enantiomer from D-glucose

Yoshio Nishimura; Shinichi Kondo; Hamao Umezawa

doi:10.1021/jo00225a045

Synthetic studies on pyrrolizidine alkaloid antitumor agents. Enantioselective synthesis of retronecine and its enantiomer from D-glucose

The Journal of Organic Chemistry ◽

10.1021/jo00225a045 ◽

1985 ◽

Vol 50 (25) ◽

pp. 5210-5214 ◽

Cited By ~ 25

Author(s):

Yoshio Nishimura ◽

Shinichi Kondo ◽

Hamao Umezawa

Keyword(s):

Antitumor Agents ◽

Pyrrolizidine Alkaloid ◽

Enantioselective Synthesis ◽

Synthetic Studies

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ChemInform Abstract: Synthetic Studies on Pyrrolizidine Alkaloid Antitumor Agents. Enantioselective Synthesis of Retronecine (I) and Its Enantiomer (II) from D-Glucose.

Chemischer Informationsdienst ◽

10.1002/chin.198619307 ◽

1986 ◽

Vol 17 (19) ◽

Author(s):

Y. NISHIMURA ◽

S. KONDO ◽

H. UMEZAWA

Keyword(s):

Antitumor Agents ◽

Pyrrolizidine Alkaloid ◽

Enantioselective Synthesis ◽

Synthetic Studies

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Synthetic Studies toward GKK1032s, Novel Antibiotic Antitumor Agents: Enantioselective Synthesis of the Fully Elaborated Tricyclic Core via an Intramolecular Diels−Alder Cycloaddition

The Journal of Organic Chemistry ◽

10.1021/jo0610208 ◽

2006 ◽

Vol 71 (18) ◽

pp. 6942-6951 ◽

Cited By ~ 22

Author(s):

Moriteru Asano ◽

Munenori Inoue ◽

Kazuhiro Watanabe ◽

Hideki Abe ◽

Tadashi Katoh

Keyword(s):

Antitumor Agents ◽

Diels Alder ◽

Enantioselective Synthesis ◽

Tricyclic Core ◽

Synthetic Studies

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Semisynthetic pyrrolizidine alkaloid N-oxide antitumor agents. Esters of heliotridine

Journal of Medicinal Chemistry ◽

10.1021/jm00403a008 ◽

1988 ◽

Vol 31 (8) ◽

pp. 1520-1526 ◽

Cited By ~ 5

Author(s):

Leon H. Zalkow ◽

Jan A. Glinski ◽

Leslie T. Gelbaum ◽

David Moore ◽

Deborah Melder ◽

...

Keyword(s):

Antitumor Agents ◽

Pyrrolizidine Alkaloid

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Synthetic Studies on the 1-Hydroxy Nortropane System,-Part III:1Total Enantioselective Synthesis of (-)-Calystegine B2

Synlett ◽

10.1055/s-1992-21548 ◽

1992 ◽

Vol 1992 (12) ◽

pp. 969-971 ◽

Cited By ~ 26

Author(s):

François-Didier Boyer ◽

Jean-Yves Lallemand

Keyword(s):

Enantioselective Synthesis ◽

System Part ◽

Synthetic Studies

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Syntheses of pyrrolizidine alkaloid and lignan lactone glycoside antitumor agents and their biological activities - From the standpoint of diastereomer and enantiomer.

Journal of Synthetic Organic Chemistry Japan ◽

10.5059/yukigoseikyokaishi.45.873 ◽

1987 ◽

Vol 45 (9) ◽

pp. 873-887 ◽

Cited By ~ 3

Author(s):

Yoshio NISHIMURA

Keyword(s):

Antitumor Agents ◽

Pyrrolizidine Alkaloid ◽

Biological Activities

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Catalytic Enantioselective Synthesis of a Pyrrolizidine–Alkaloid-Inspired Compound Collection with Antiplasmodial Activity

The Journal of Organic Chemistry ◽

10.1021/acs.joc.7b03202 ◽

2018 ◽

Vol 83 (13) ◽

pp. 7033-7041 ◽

Cited By ~ 4

Author(s):

Zhi-Jun Jia ◽

Hiroshi Takayama ◽

Yushi Futamura ◽

Harumi Aono ◽

Jonathan O. Bauer ◽

...

Keyword(s):

Pyrrolizidine Alkaloid ◽

Enantioselective Synthesis ◽

Antiplasmodial Activity ◽

Compound Collection

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Synthetic Studies toward Jatrophane Diterpenes fromEuphorbia characias. Enantioselective Synthesis of (−)-15-O-Acetyl-3-O-propionyl-17-norcharaciol†

The Journal of Organic Chemistry ◽

10.1021/jo802581g ◽

2009 ◽

Vol 74 (4) ◽

pp. 1698-1708 ◽

Cited By ~ 30

Author(s):

Hannes Helmboldt ◽

Martin Hiersemann

Keyword(s):

Enantioselective Synthesis ◽

Synthetic Studies

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ChemInform Abstract: SYNTHETIC STUDIES ON THE CARBOMYCINS (MAGNAMYCINS): AN EXCEPTION TO THE ENANTIOSELECTIVE SYNTHESIS OF β-ALKYL CARBOXYLIC ACIDS VIA CHIRAL OXAZOLINES

Chemischer Informationsdienst ◽

10.1002/chin.198206184 ◽

1982 ◽

Vol 13 (6) ◽

Author(s):

F. E. ZIEGLER ◽

P. J. GILLIGAN

Keyword(s):

Carboxylic Acids ◽

Enantioselective Synthesis ◽

Synthetic Studies

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ChemInform Abstract: Synthetic Studies on Spiroketal Natural Products. Part 2. An Enantioselective Synthesis of (R)- and (S)-1,7-Dioxaspiro(5.5)undecane.

ChemInform ◽

10.1002/chin.198919314 ◽

1989 ◽

Vol 20 (19) ◽

Author(s):

C. IWATA ◽

M. FUJITA ◽

T. KUROKI ◽

K. HATTORI ◽

S. UCHIDA ◽

...

Keyword(s):

Natural Products ◽

Enantioselective Synthesis ◽

Synthetic Studies

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ChemInform Abstract: An Efficient Enantioselective Synthesis of Indicine N-Oxide (VI), an Antitumor Pyrrolizidine Alkaloid.

ChemInform ◽

10.1002/chin.199324289 ◽

2010 ◽

Vol 24 (24) ◽

pp. no-no

Author(s):

T. OGAWA ◽

H. NIWA ◽

K. YAMADA

Keyword(s):

Pyrrolizidine Alkaloid ◽

Enantioselective Synthesis

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