Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

Alessandro Dondoni; Daniela Perrone; M. Teresa Semola

doi:10.1021/jo00129a037

Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease

The Journal of Organic Chemistry ◽

10.1021/jo00129a037 ◽

1995 ◽

Vol 60 (24) ◽

pp. 7927-7933 ◽

Cited By ~ 21

Author(s):

Alessandro Dondoni ◽

Daniela Perrone ◽

M. Teresa Semola

Keyword(s):

Aspartic Protease ◽

Hiv 1

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Evaluation of complexation energies between aspartic protease of HIV-1 and its hexapeptide inhibitors including the effect of solvation

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(01)81026-x ◽

1993 ◽

Vol 3 (10) ◽

pp. 2105-2112 ◽

Cited By ~ 6

Author(s):

Stanislav Miertus

Keyword(s):

Aspartic Protease ◽

Hiv 1

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Interactions of ligands with macromolecules: Rational design of specific inhibitors of aspartic protease of HIV-1

Macromolecular Chemistry and Physics ◽

10.1002/1521-3935(200207)203:10/11<1650::aid-macp1650>3.0.co;2-e ◽

2002 ◽

Vol 203 (10-11) ◽

pp. 1650-1657 ◽

Cited By ~ 8

Author(s):

Vladimir Frecer ◽

Stanislav Miertus

Keyword(s):

Rational Design ◽

Aspartic Protease ◽

Hiv 1 ◽

Specific Inhibitors

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Computational Study of Triterpenoids of Ganoderma lucidum with Aspartic Protease Enzymes for Discovering HIV-1 and Plasmepsin Inhibitors

International Journal of Chemistry ◽

10.5539/ijc.v7n1p62 ◽

2015 ◽

Vol 7 (1) ◽

Cited By ~ 6

Author(s):

Devinna Kang ◽

Mutakin Mutakin ◽

Jutti Levita

Keyword(s):

Ganoderma Lucidum ◽

Computational Study ◽

Aspartic Protease ◽

Hiv 1

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Inhibitors of HIV-1 Protease: Current State of the Art 10 Years After their Introduction. From Antiretroviral Drugs to Antifungal, Antibacterial and Antitumor Agents Based on Aspartic Protease Inhibitors

Current Medicinal Chemistry ◽

10.2174/092986707782360141 ◽

2007 ◽

Vol 14 (26) ◽

pp. 2734-2748 ◽

Cited By ~ 84

Author(s):

Antonio Mastrolorenzo ◽

Stefano Rusconi ◽

Andrea Scozzafava ◽

Giuseppe Barbaro ◽

Claudiu Supuran

Keyword(s):

Protease Inhibitors ◽

Antitumor Agents ◽

State Of The Art ◽

Antiretroviral Drugs ◽

Aspartic Protease ◽

Current State ◽

Hiv 1

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Nonsymmetrical cyclic urea inhibitors of HIV-1 aspartic protease

Drug Discovery Today ◽

10.1016/j.drudis.2006.04.004 ◽

2006 ◽

Vol 11 (11-12) ◽

pp. 569-570

Author(s):

Paul Edwards

Keyword(s):

Aspartic Protease ◽

Hiv 1

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A Computational Study of the Resistance of HIV-1 Aspartic Protease to the Inhibitors ABT-538 and VX-478 and Design of New Analogues

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1997.8008 ◽

1998 ◽

Vol 242 (3) ◽

pp. 545-551 ◽

Cited By ~ 17

Author(s):

Anil C. Nair ◽

Stanislav Miertus ◽

Alessandro Tossi ◽

Domenico Romeo

Keyword(s):

Computational Study ◽

Aspartic Protease ◽

Hiv 1

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ChemInform Abstract: Thiazole-Based Stereoselective Routes to Leucine and Phenylalanine Hydroxyethylene Dipeptide Isostere Inhibitors of Renin and HIV-1 Aspartic Protease.

ChemInform ◽

10.1002/chin.199615221 ◽

2010 ◽

Vol 27 (15) ◽

pp. no-no

Author(s):

A. DONDONI ◽

D. PERRONE ◽

M. T. SEMOLA

Keyword(s):

Aspartic Protease ◽

Hiv 1

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Combinatorial design of nonsymmetrical cyclic urea inhibitors of aspartic protease of HIV-1

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.06.026 ◽

2005 ◽

Vol 13 (18) ◽

pp. 5492-5501 ◽

Cited By ~ 12

Author(s):

Vladimír Frecer ◽

Enrico Burello ◽

Stanislav Miertus

Keyword(s):

Aspartic Protease ◽

Combinatorial Design ◽

Hiv 1

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Interaction of HIV-1 aspartic protease with its inhibitor, by molecular dynamics andab initiofragment molecular orbital method

Journal of Synchrotron Radiation ◽

10.1107/s0909049507068586 ◽

2008 ◽

Vol 15 (3) ◽

pp. 239-242 ◽

Cited By ~ 1

Author(s):

Kazuo Koyano ◽

Tatsuya Nakano

Keyword(s):

Molecular Dynamics ◽

Molecular Orbital ◽

Aspartic Protease ◽

Orbital Method ◽

Molecular Orbital Method ◽

Hiv 1

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Computational Design of New Cyclic Urea Inhibitors for Improved Binding of HIV-1 Aspartic Protease

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.2000.2139 ◽

2000 ◽

Vol 268 (2) ◽

pp. 384-389 ◽

Cited By ~ 3

Author(s):

Bhanuprakash Kotamarthi ◽

Irena Bonin ◽

Fabio Benedetti ◽

Stanislav Miertus

Keyword(s):

Computational Design ◽

Aspartic Protease ◽

Hiv 1

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