A Concluding Specification of the Dimensions of the Active Site Model of Pig Liver Esterase

1994 ◽  
Vol 59 (10) ◽  
pp. 2729-2732 ◽  
Author(s):  
Louis Provencher ◽  
J. Bryan Jones
Keyword(s):  
Active Site ◽  
Pig Liver ◽  
Pig Liver Esterase ◽  
Site Model ◽  
Liver Esterase ◽  
Active Site Model

Enzymic Hydrolysis of Methyl 2,3-O-Acetyl-5-Deoxy-α and β-D-Xylofuranosides - An Active-Site Model of Pig Liver Esterase

1997 ◽  
Vol 16 (7) ◽  
pp. 1011-1028 ◽  
Author(s):  
Jitka Moravcová ◽  
Zita Vanclová ◽  
Jindra Čapková ◽  
Karel Kefurt ◽  
Jan Staněk
Keyword(s):  
Active Site ◽  
Enzymic Hydrolysis ◽  
Pig Liver ◽  
Pig Liver Esterase ◽  
Site Model ◽  
Liver Esterase ◽  
Active Site Model ◽  
Hydrolysis Of

Porcine Liver Esterase-Catalyzed Hydrolysis of Methyl Tri-O-acetyl-β-D-arabinopyranoside, Methyl Tri-O-acetyl-β-D-ribopyranoside and Methyl Tri-O-acetyl-β-D-ribofuranoside

2000 ◽  
Vol 65 (10) ◽  
pp. 1619-1629 ◽  
Author(s):  
Jitka Moravcová ◽  
Karel Kefurt ◽  
Romana Hladůvková ◽  
Jan Staněk
Keyword(s):  
Active Site ◽  
Michaelis Constant ◽  
Porcine Liver ◽  
Site Model ◽  
Liver Esterase ◽  
Preparative Yield ◽  
Active Site Model ◽  
Catalyzed Reactions ◽  
Hydrolysis Of ◽  
Porcine Liver Esterase

Methyl 2,3,4-tri-O-acetyl-β-D-arabinopyranoside (1), methyl 2,3,4-tri-O-acetyl-β-D-ribopyranoside (2), and methyl 2,3,5-tri-O-acetyl-β-D-ribofuranoside (3) were deacetylated in porcine liver esterase-catalyzed reactions. Triacetate 1 gave methyl 3,4-di-O-acetyl-β-D-arabinopyranoside in 70% preparative yield while the regioselectivities found for the substrates 2 and 3 were substantially lower. Both the Michaelis constant and maximum rate were calculated for deacetylation of 1, 2, and 3. The results were interpreted using an active site model for the esterase proposed by Jones.

Enantiospecific enzyme-catalysed resolution of novel N,N-disubstituted α-amino acid phenolic ester derivatives using pig liver esterase

2001 ◽  
pp. 362-365 ◽  
Author(s):  
D. Jonathan Bennett ◽  
Kirsteen I. Buchanan ◽  
Andrew Cooke ◽  
Ola Epemolu ◽  
Niall M. Hamilton ◽  
...  
Keyword(s):  
Amino Acid ◽  
Pig Liver ◽  
Pig Liver Esterase ◽  
Liver Esterase
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