Free-radical annelation in the synthesis of bicyclic .beta.-lactams. 7. A one-pot, four-step, sequential reaction

1993 ◽  
Vol 58 (21) ◽  
pp. 5581-5582 ◽  
Author(s):  
Eric Bosch ◽  
Mario D. Bachi
Keyword(s):  
Free Radical ◽  
Beta Lactams ◽  
One Pot ◽  
Sequential Reaction

Thermo-sensitivity of hybrid nanogels for specific endogenous hydrogen sulfide detection and efficient flash chill treatment

2021 ◽  
Author(s):  
Xu-hao Sun ◽  
Qiu-bo Wang ◽  
Li Pan ◽  
Yilin Mu ◽  
Xian Zhang ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Free Radical ◽  
Precipitation Method ◽  
Carboxyl Group ◽  
One Pot ◽  
Thermo Sensitivity

Thermo-responsive nanogels, Poly (NIPAM-AAM) were prepared by a facile method of free radical one-pot precipitation method based on monomeric N-isopropylacrylamide (NIPAM). At the same time, the surface carboxyl group-modified fluorescent...

Asymmetric synthesis of dihydrocarbazoles through Friedel-Crafts alkylation/annulation sequential reaction of indoles

2021 ◽  
Author(s):  
Linfeng Hu ◽  
Weidi Cao ◽  
Kaixuan Wang ◽  
Xiaohua Liu ◽  
Xiaoming Feng
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot ◽  
Sequential Reaction

An enantioselective tandem Friedel-Crafts alkylation/annulation of indoles with diazoacetoacetate enones is realized in one pot. A series of dihydrocarbazoles were obtained in moderate yields with good to excellent ee values...

One-Pot Sequential Reaction using Resin-Supported Acid and Base Catalysts

Synfacts ◽  
2007 ◽  
Vol 2007 (4) ◽  
pp. 0439-0439
Author(s):  
K. Kudo ◽  
K. Akagawa ◽  
S. Sakamoto
Keyword(s):  
One Pot ◽  
Sequential Reaction ◽  
Base Catalysts ◽  
Acid And Base

ChemInform Abstract: One-Pot Synthesis of α-Amino Acids Based on Free Radical-Mediated Carbon-Carbon Bond Formation.

ChemInform ◽  
2010 ◽  
Vol 30 (14) ◽  
pp. no-no
Author(s):  
Hideto Miyabe ◽  
Naoko Yoshioka ◽  
Masafumi Ueda ◽  
Takeaki Naito
Keyword(s):  
Amino Acids ◽  
Free Radical ◽  
Bond Formation ◽  
One Pot ◽  
Carbon Bond ◽  
One Pot Synthesis ◽  
Carbon Carbon Bond

Silver-hydroxyapatite nanocomposites prepared by three sequential reaction steps in one pot and their bioactivities in vitro

2020 ◽  
pp. 111655
Author(s):  
Jingwen Hou ◽  
Yongjia Liu ◽  
Zhihui Han ◽  
Dianwen Song ◽  
Bangshang Zhu
Keyword(s):  
One Pot ◽  
Sequential Reaction

Green One-Pot Asymmetric Synthesis of Peptidomimetics via Sequential Organocatalyzed Aziridination and Passerini Multicomponent Reaction

Synthesis ◽  
2019 ◽  
Vol 52 (07) ◽  
pp. 1076-1086
Author(s):  
Deborah A. dos Santos ◽  
Allan R. da Silva ◽  
Javier Ellena ◽  
Cecilia C. P. da Silva ◽  
Marcio W. Paixão ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Protease Inhibitors ◽  
Multicomponent Reaction ◽  
Efficient Method ◽  
Cysteine Protease ◽  
Heterocyclic Compounds ◽  
Solvent Mixture ◽  
Cysteine Protease Inhibitors ◽  
One Pot ◽  
Sequential Reaction

Peptidomimetics containing an aziridine moiety have been reported as potent cysteine protease inhibitors. In this sense, the development of stereoselective and sustainable synthetic strategies to obtain three-membered N-heterocyclic compounds has gained importance in the last decades. In this work, an efficient method was designed to achieve highly functionalized aziridine peptidomimetics via a sequential reaction, which involves the organocatalytic aziridination of α,β-unsaturated aldehydes followed by the Passerini multicomponent reaction in an environmentally friendly solvent mixture (ethanol: water).

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