Catalytic asymmetric synthesis of quarternary carbon centers. Palladium-catalyzed formation of either enantiomer of spirooxindoles and related spirocyclics using a single enantiomer of a chiral diphosphine ligand

Atsuyuki Ashimori; Larry E. Overman

doi:10.1021/jo00043a005

Catalytic asymmetric synthesis of quarternary carbon centers. Palladium-catalyzed formation of either enantiomer of spirooxindoles and related spirocyclics using a single enantiomer of a chiral diphosphine ligand

The Journal of Organic Chemistry ◽

10.1021/jo00043a005 ◽

1992 ◽

Vol 57 (17) ◽

pp. 4571-4572 ◽

Cited By ~ 142

Author(s):

Atsuyuki Ashimori ◽

Larry E. Overman

Keyword(s):

Asymmetric Synthesis ◽

Diphosphine Ligand ◽

Carbon Centers ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric

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ChemInform Abstract: Catalytic Asymmetric Synthesis of Quarternary Carbon Centers. Palladium-Catalyzed Formation of Either Enantiomer of Spirooxindoles and Related Spirocyclics Using a Single Enantiomer of a Chiral Diphosphine Ligand.

ChemInform ◽

10.1002/chin.199302176 ◽

2010 ◽

Vol 24 (2) ◽

pp. no-no

Author(s):

A. ASHIMORI ◽

L. E. OVERMAN

Keyword(s):

Asymmetric Synthesis ◽

Diphosphine Ligand ◽

Carbon Centers ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric

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Palladium-catalyzed asymmetric arylation of 4,7-dihydro-1,3-dioxepin. Catalytic asymmetric synthesis of γ-butyrolactone derivatives

Tetrahedron Letters ◽

10.1016/0040-4039(94)88030-1 ◽

1994 ◽

Vol 35 (8) ◽

pp. 1227-1230 ◽

Cited By ~ 50

Author(s):

Yuichi Koga ◽

Mikiko Sodeoka ◽

Masakatsu Shibasaki

Keyword(s):

Asymmetric Synthesis ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric

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Synthesis of fluorinated donepezil by palladium-catalyzed decarboxylative allylation of α-fluoro-β-keto ester with tri-substituted heterocyclic alkene and the self-disproportionation of its enantiomers

RSC Advances ◽

10.1039/c6ra21253k ◽

2016 ◽

Vol 6 (88) ◽

pp. 85058-85062 ◽

Cited By ~ 10

Author(s):

Mayaka Maeno ◽

Hiroya Kondo ◽

Etsuko Tokunaga ◽

Norio Shibata

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Asymmetric Synthesis ◽

Therapeutic Agent ◽

The Self ◽

Keto Ester ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric ◽

Decarboxylative Allylation

Catalytic asymmetric synthesis of fluorinated donepezil, a promising new therapeutic agent for Alzheimer's disease, was achieved.

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ChemInform Abstract: A Catalytic Asymmetric Synthesis of α-Methylene Lactones by the Palladium-Catalyzed Carbonylation of Prochiral Alkenyl Halides.

ChemInform ◽

10.1002/chin.199217137 ◽

2010 ◽

Vol 23 (17) ◽

pp. no-no

Author(s):

T. SUZUKI ◽

Y. UOZUMI ◽

M. SHIBASAKI

Keyword(s):

Asymmetric Synthesis ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric

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Palladium-catalyzed asymmetric 1,4-disilylation of .alpha.,.beta.-unsaturated ketones: catalytic asymmetric synthesis of .beta.-hydroxy ketones

Journal of the American Chemical Society ◽

10.1021/ja00224a057 ◽

1988 ◽

Vol 110 (16) ◽

pp. 5579-5581 ◽

Cited By ~ 92

Author(s):

Tamio. Hayashi ◽

Yonetatsu. Matsumoto ◽

Yoshihiko. Ito

Keyword(s):

Asymmetric Synthesis ◽

Unsaturated Ketones ◽

Catalytic Asymmetric Synthesis ◽

Hydroxy Ketones ◽

Palladium Catalyzed ◽

Alpha Beta ◽

Catalytic Asymmetric

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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)-α,β-Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates

Journal of the American Chemical Society ◽

10.1021/ja980787h ◽

1998 ◽

Vol 120 (26) ◽

pp. 6488-6499 ◽

Cited By ~ 133

Author(s):

Atsuyuki Ashimori ◽

Benoit Bachand ◽

Michael A. Calter ◽

Steven P. Govek ◽

Larry E. Overman ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Quaternary Carbon ◽

Heck Reactions ◽

Carbon Centers ◽

Catalytic Asymmetric Synthesis ◽

Mechanistic Investigations ◽

Catalytic Asymmetric

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Catalytic Asymmetric Synthesis of Quaternary Carbon Centers by Intramolecular Heck Reaction. Synthetic Developments and Mechanistic Studies.

Journal of Synthetic Organic Chemistry Japan ◽

10.5059/yukigoseikyokaishi.58.718 ◽

2000 ◽

Vol 58 (8) ◽

pp. 718-727 ◽

Cited By ~ 5

Author(s):

Atsuyuki Ashimori ◽

Larry E. Overman

Keyword(s):

Asymmetric Synthesis ◽

Heck Reaction ◽

Mechanistic Studies ◽

Quaternary Carbon ◽

Carbon Centers ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric ◽

Intramolecular Heck Reaction

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Catalytic asymmetric synthesis of benzylic quaternary carbon centers. An efficient synthesis of (-)-eptazocine

Journal of the American Chemical Society ◽

10.1021/ja00071a079 ◽

1993 ◽

Vol 115 (18) ◽

pp. 8477-8478 ◽

Cited By ~ 63

Author(s):

Toshiyasu Takemoto ◽

Mikiko Sodeoka ◽

Hiroaki Sasai ◽

Masakatsu Shibasaki

Keyword(s):

Asymmetric Synthesis ◽

Efficient Synthesis ◽

Quaternary Carbon ◽

Carbon Centers ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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ChemInform Abstract: Catalytic Asymmetric Synthesis of Optically Active Alkenes by Palladium-Catalyzed Asymmetric Reduction of Racemic Allylic Esters with Formic Acid.

ChemInform ◽

10.1002/chin.199647027 ◽

2010 ◽

Vol 27 (47) ◽

pp. no-no

Author(s):

T. HAYASHI ◽

M. KAWATSURA ◽

H. IWAMURA ◽

Y. YAMAURA ◽

Y. UOZUMI

Keyword(s):

Formic Acid ◽

Asymmetric Synthesis ◽

Asymmetric Reduction ◽

Optically Active ◽

Catalytic Asymmetric Synthesis ◽

Palladium Catalyzed ◽

Catalytic Asymmetric ◽

Allylic Esters

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Enantioselective Suzuki Reactions: Catalytic Asymmetric Synthesis of Compounds Containing Quaternary Carbon Centers.

ChemInform ◽

10.1002/chin.200427032 ◽

2004 ◽

Vol 35 (27) ◽

Author(s):

Michael C. Willis ◽

Luke H. W. Powell ◽

Christelle K. Claverie ◽

Simon J. Watson

Keyword(s):

Asymmetric Synthesis ◽

Quaternary Carbon ◽

Carbon Centers ◽

Suzuki Reactions ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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