A facile synthesis of optically active 3-ethyl- and 3-butylphthalides via catalytic enantioselective addition of dialkylzinc reagents to o-phthalaldehyde

1992 ◽  
Vol 57 (2) ◽  
pp. 742-744 ◽  
Author(s):  
Makoto Watanabe ◽  
Norifumi Hashimoto ◽  
Shuki Araki ◽  
Yasuo Butsugan
Keyword(s):  
Optically Active ◽  
Facile Synthesis ◽  
Enantioselective Addition

Facile synthesis of optically active polyaniline and polytoluidine

Polymer ◽  
1996 ◽  
Vol 37 (2) ◽  
pp. 359-362 ◽  
Author(s):  
Mir Reza Majidi ◽  
Leon A.P. Kane-Maguire ◽  
Gordon G.G. Wallace
Keyword(s):  
Optically Active ◽  
Facile Synthesis

ChemInform Abstract: An Efficient and Facile Synthesis of Racemic and Optically Active Fexofenadine.

ChemInform ◽  
2010 ◽  
Vol 29 (29) ◽  
pp. no-no
Author(s):  
Q. K. FANG ◽  
C. H. SENANAYAKE ◽  
H. S. WILKINSON ◽  
S. A. WALD ◽  
H. LI
Keyword(s):  
Optically Active ◽  
Facile Synthesis

scholarly journals Facile synthesis of optically active oxindoles by copper-catalyzed asymmetric monotosylation of prochiral 1,3-diols

2010 ◽  
Vol 21 (11-12) ◽  
pp. 1370-1373 ◽  
Author(s):  
Masami Kuriyama ◽  
Satoko Tanigawa ◽  
Yuki Kubo ◽  
Yosuke Demizu ◽  
Osamu Onomura
Keyword(s):  
Optically Active ◽  
Facile Synthesis

Facile Synthesis of Optically Active Homocysteine from Methionine

2000 ◽  
Vol 29 (5) ◽  
pp. 468-469 ◽  
Author(s):  
Tadashi Shiraiwa ◽  
Kazuo Nakagawa ◽  
Norito Kanemoto
Keyword(s):  
Optically Active ◽  
Facile Synthesis

Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids to Glyoxylates: Access to Optically Active Substituted Mandelic Acid Esters

Synlett ◽  
2019 ◽  
Vol 30 (14) ◽  
pp. 1693-1697
Author(s):  
Diao Chen ◽  
Jian-Guo Liu ◽  
Xu Zhang ◽  
Ming-Hua Xu
Keyword(s):  
Catalytic System ◽  
Mandelic Acid ◽  
Optically Active ◽  
Antiplatelet Drug ◽  
Reaction Conditions ◽  
Formal Synthesis ◽  
Arylboronic Acids ◽  
Synthetic Utility ◽  
Enantioselective Addition ◽  
Acid Esters

A rhodium-catalyzed enantioselective addition of glyoxylates to arylboronic acids promoted by a simple chiral sulfinamide-based olefin ligand under mild reaction conditions is described. The reaction provides access to a variety of optically active substituted mandelic acid esters in good yields with up to 83% ee. The catalytic system is also applicable to pyruvate addition. The synthetic utility of this method is highlighted by a formal synthesis of the antiplatelet drug clopidogrel.

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