4,5-Dihydro-1,2,4-triazolo[1,5-a]quinoxalin-4-ones:  Excitatory Amino Acid Antagonists with Combined Glycine/NMDA and AMPA Receptor Affinity

Daniela Catarzi; Vittoria Colotta; Flavia Varano; Lucia Cecchi; Guido Filacchioni; Alessandro Galli; Chiara Costagli

doi:10.1021/jm981102r

4,5-Dihydro-1,2,4-triazolo[1,5-a]quinoxalin-4-ones: Excitatory Amino Acid Antagonists with Combined Glycine/NMDA and AMPA Receptor Affinity

Journal of Medicinal Chemistry ◽

10.1021/jm981102r ◽

1999 ◽

Vol 42 (13) ◽

pp. 2478-2484 ◽

Cited By ~ 21

Author(s):

Daniela Catarzi ◽

Vittoria Colotta ◽

Flavia Varano ◽

Lucia Cecchi ◽

Guido Filacchioni ◽

...

Keyword(s):

Amino Acid ◽

Ampa Receptor ◽

Excitatory Amino Acid ◽

Receptor Affinity ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Effects ofin situadministration of excitatory amino acid antagonists on rapid microglial and astroglial reactions in rat hippocampus following traumatic brain injury

Neurological Research ◽

10.1179/016164107x251745 ◽

2008 ◽

Vol 30 (4) ◽

pp. 420-429 ◽

Cited By ~ 9

Author(s):

Takeshi Suma ◽

Morimichi Koshinaga ◽

Masamichi Fukushima ◽

Tsuneo Kano ◽

Yoichi Katayama

Keyword(s):

Traumatic Brain Injury ◽

Amino Acid ◽

Brain Injury ◽

Excitatory Amino Acid ◽

Rat Hippocampus ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Excitatory Amino Acid Antagonists and Pentylenetetrazol-induced Seizures During Ontogenesis. IV. Effects of CGP 39551

Pharmacology Biochemistry and Behavior ◽

10.1016/s0091-3057(96)00245-6 ◽

1997 ◽

Vol 56 (3) ◽

pp. 493-498 ◽

Cited By ~ 10

Author(s):

Libor Velíšek ◽

Dana Vachová ◽

Pavel Mareš

Keyword(s):

Amino Acid ◽

Excitatory Amino Acid ◽

Cgp 39551 ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Effects of excitatory amino acid antagonists on dendrotoxin-induced increases in neurotransmitter release and epileptiform bursting in rat hippocampus in vitro

Journal of Neuroscience Research ◽

10.1002/(sici)1097-4547(19970615)48:6<499::aid-jnr2>3.0.co;2-5 ◽

1997 ◽

Vol 48 (6) ◽

pp. 499-506 ◽

Cited By ~ 9

Author(s):

F. Dorandeu ◽

J. Wetherell ◽

I. Pernot-Marino ◽

J.E.H. Tattersall ◽

P. Fosbraey ◽

...

Keyword(s):

Amino Acid ◽

Neurotransmitter Release ◽

Excitatory Amino Acid ◽

Rat Hippocampus ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Behavioural and eeg effects of some excitatory amino acid antagonists

Pharmacological Research Communications ◽

10.1016/s0031-6989(88)80017-1 ◽

1988 ◽

Vol 20 (5) ◽

pp. 409-410 ◽

Cited By ~ 1

Author(s):

M. Benedetti ◽

S. Sagratella ◽

A. Scotti de Carolis

Keyword(s):

Amino Acid ◽

Excitatory Amino Acid ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

Trends in Pharmacological Sciences ◽

10.1016/0165-6147(93)90005-5 ◽

1993 ◽

Vol 14 (9) ◽

pp. 325-331 ◽

Cited By ~ 217

Author(s):

Michael A. Rogawski

Keyword(s):

Amino Acid ◽

Therapeutic Potential ◽

Excitatory Amino Acid ◽

Channel Blockers ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

Brain Research ◽

10.1016/0006-8993(90)91195-m ◽

1990 ◽

Vol 506 (1) ◽

pp. 31-39 ◽

Cited By ~ 260

Author(s):

Anthony H. Dickenson ◽

Ann F. Sullivan

Keyword(s):

Amino Acid ◽

Dorsal Horn ◽

Excitatory Amino Acid ◽

Differential Effects ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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The role of putative excitatory amino acid neurotransmitters in the initiation of locomotion in the lamprey spinal cord. I. The effects of excitatory amino acid antagonists

Brain Research ◽

10.1016/0006-8993(85)91229-6 ◽

1985 ◽

Vol 360 (1-2) ◽

pp. 139-148 ◽

Cited By ~ 55

Author(s):

Lennart Brodin ◽

Sten Grillner

Keyword(s):

Spinal Cord ◽

Amino Acid ◽

Excitatory Amino Acid ◽

Amino Acid Neurotransmitters ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Hypoxic Neurodegeneration in Culture: Calcium Influx, Electron Microscopy, and Neuroprotection with Excitatory Amino Acid Antagonists

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1992.tb24563.x ◽

1992 ◽

Vol 648 (1 Neurotoxins a) ◽

pp. 303-305 ◽

Cited By ~ 7

Author(s):

FRANK W. MARCOUX ◽

MARK L. WEBER ◽

ALBERT W. PROBERT ◽

MARK A. DOMINICK

Keyword(s):

Electron Microscopy ◽

Amino Acid ◽

Excitatory Amino Acid ◽

Calcium Influx ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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The pharmacology of excitatory amino acid antagonists in an animal model of stroke

European Neuropsychopharmacology ◽

10.1016/0924-977x(94)90091-4 ◽

1994 ◽

Vol 4 (3) ◽

pp. 279-281

Author(s):

R. Gill

Keyword(s):

Animal Model ◽

Amino Acid ◽

Excitatory Amino Acid ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism

Life Sciences ◽

10.1016/0024-3205(90)90376-3 ◽

1990 ◽

Vol 47 (18) ◽

pp. PL91-PL97 ◽

Cited By ~ 80

Author(s):

W.C. Graham ◽

R.G. Robertson ◽

M.A. Sambrook ◽

A.R. Crossman

Keyword(s):

Amino Acid ◽

Excitatory Amino Acid ◽

Motor Symptoms ◽

Amino Acid Antagonists ◽

Excitatory Amino Acid Antagonists

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