4-Alkynylphenyl Imidazolylpropyl Ethers as Selective Histamine H3-Receptor Antagonists with High Oral Central Nervous System Activity

Michael Krause; Xavier Ligneau; Holger Stark; Monique Garbarg; Jean-Charles Schwartz; Walter Schunack

doi:10.1021/jm9802970

4-Alkynylphenyl Imidazolylpropyl Ethers as Selective Histamine H3-Receptor Antagonists with High Oral Central Nervous System Activity

Journal of Medicinal Chemistry ◽

10.1021/jm9802970 ◽

1998 ◽

Vol 41 (21) ◽

pp. 4171-4176 ◽

Cited By ~ 17

Author(s):

Michael Krause ◽

Xavier Ligneau ◽

Holger Stark ◽

Monique Garbarg ◽

Jean-Charles Schwartz ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

System Activity ◽

Nervous System Activity ◽

H3 Receptor ◽

Central Nervous System Activity ◽

Histamine H3

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4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b01462 ◽

2019 ◽

Vol 62 (23) ◽

pp. 10848-10866 ◽

Cited By ~ 2

Author(s):

Gábor Wágner ◽

Tamara A. M. Mocking ◽

Marta Arimont ◽

Gustavo Provensi ◽

Barbara Rani ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Histamine H3 Receptor ◽

System Activity ◽

High Affinity ◽

Nervous System Activity ◽

H3 Receptor ◽

Central Nervous System Activity ◽

Histamine H3

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Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous system

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2004.05.001 ◽

2004 ◽

Vol 103 (1) ◽

pp. 1-20 ◽

Cited By ~ 95

Author(s):

J.M Witkin ◽

D.L Nelson

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Receptor Antagonists ◽

Histamine H3 Receptor ◽

H3 Receptor ◽

The Central Nervous System ◽

Cognitive Deficiencies ◽

Histamine H3

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Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding

European Journal of Pharmacology ◽

10.1016/0014-2999(94)90197-x ◽

1994 ◽

Vol 253 (3) ◽

pp. 237-244 ◽

Cited By ~ 22

Author(s):

Smita Patel ◽

Kerry L. Chapman ◽

Anne Heald ◽

Alison J. Smith ◽

Stephen B. Freedman

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Ex Vivo ◽

Receptor Antagonists ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity ◽

Cckb Receptor

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Radiation-Free Allogeneic Conditioning with Fludarabine, Carmustine, and Thiotepa for Acute Lymphoblastic Leukemia and Other Hematologic Malignancies Necessitating Enhanced Central Nervous System Activity

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2012.02.016 ◽

2012 ◽

Vol 18 (9) ◽

pp. 1430-1437 ◽

Cited By ~ 9

Author(s):

Petros Christopoulos ◽

Hartmut Bertz ◽

Gabriele Ihorst ◽

Reinhard Marks ◽

Ralph Wäsch ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Acute Lymphoblastic Leukemia ◽

Lymphoblastic Leukemia ◽

Hematologic Malignancies ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity

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Some Aspects of the Central Nervous System Activity of a Series of Urazole Derivatives**Department of Pharmacology, College of Medicine, State University of Iowa, Iowa City

Journal of the American Pharmaceutical Association (Scientific ed ) ◽

10.1002/jps.3030480215 ◽

1959 ◽

Vol 48 (2) ◽

pp. 122-126 ◽

Cited By ~ 6

Author(s):

C.L. Mitchell ◽

H.H. Keasling ◽

E.G. Gross

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Iowa City ◽

State University ◽

University Of Iowa ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity ◽

The Central Nervous System

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Synthesis and central nervous system activity of quinazolones related to 2-methyl-3-(o-tolyl)-4(3H)-quinazolone (methaqualone)

Journal of Medicinal Chemistry ◽

10.1021/jm00213a013 ◽

1977 ◽

Vol 20 (3) ◽

pp. 379-386 ◽

Cited By ~ 27

Author(s):

I. R. Ager ◽

D. R. Harrison ◽

P. D. Kennewell ◽

J. B. Taylor

Keyword(s):

Central Nervous System ◽

Nervous System ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity

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Electrophysiological Studies on the Effect of Urea on Central Nervous System Activity

The Journal of Kansai Medical University ◽

10.5361/jkmu1956.34.4_870 ◽

1982 ◽

Vol 34 (4) ◽

pp. 870-902

Author(s):

Hiroshi Yoshida

Keyword(s):

Central Nervous System ◽

Nervous System ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity ◽

Electrophysiological Studies

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ChemInform Abstract: SYNTHESIS AND CENTRAL NERVOUS SYSTEM ACTIVITY OF 1,2,3,4-TETRAHYDRO-1-AMINO-4-PHENYLNAPHTHALENES

Chemischer Informationsdienst ◽

10.1002/chin.197436215 ◽

1974 ◽

Vol 5 (36) ◽

pp. no-no

Author(s):

L. A. WALTER ◽

W. K. CHANG ◽

J. KENNEY ◽

I. DOUVAN

Keyword(s):

Central Nervous System ◽

Nervous System ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity

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Central nervous system activity of Leucas inflata Benth. in mice

Phytomedicine ◽

10.1078/09447110260573128 ◽

2002 ◽

Vol 9 (6) ◽

pp. 501-507 ◽

Cited By ~ 9

Author(s):

M.H. Al-Yousuf ◽

B.H. Ali ◽

A.K. Bashir ◽

M.O.M. Tanira ◽

G. Blunden

Keyword(s):

Central Nervous System ◽

Nervous System ◽

System Activity ◽

Nervous System Activity ◽

Central Nervous System Activity

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Complementary Examinations of the Central Nervous System Activity in the Apallic Syndrome

The Apallic Syndrome - Monographien aus dem Gesamtgebiete der Psychiatrie ◽

10.1007/978-3-642-81151-7_25 ◽

1977 ◽

pp. 160-163

Author(s):

S. Mingrino

Keyword(s):

Central Nervous System ◽

Nervous System ◽

System Activity ◽

Apallic Syndrome ◽

Nervous System Activity ◽

Central Nervous System Activity ◽

The Central Nervous System

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