Design, Synthesis, Structure−Activity Relationships, and Biological Characterization of Novel Arylalkoxyphenylalkylamine σ Ligands as Potential Antipsychotic Drugs

1999 ◽  
Vol 42 (6) ◽  
pp. 1076-1087 ◽  
Author(s):  
Atsuro Nakazato ◽  
Kohmei Ohta ◽  
Yoshinori Sekiguchi ◽  
Shigeru Okuyama ◽  
Shigeyuki Chaki ◽  
...  
Keyword(s):  
Antipsychotic Drugs ◽  
Biological Characterization ◽  
Design Synthesis ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure–Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist

2017 ◽  
Vol 60 (23) ◽  
pp. 9641-9652 ◽  
Author(s):  
Salvatore Di Maro ◽  
Francesco Saverio Di Leva ◽  
Anna Maria Trotta ◽  
Diego Brancaccio ◽  
Luigi Portella ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Receptor Type ◽  
Biological Characterization ◽  
Cxcr4 Antagonist ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Phytotoxic Terpenes Produced by Phytopathogenic Fungi and Allelopathic Plants

2014 ◽  
Vol 9 (3) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Alessio Cimmino ◽  
Anna Andolfi ◽  
Antonio Evidente
Keyword(s):  
Mode Of Action ◽  
Potential Application ◽  
Fungal Pathogens ◽  
Phytopathogenic Fungi ◽  
Biological Characterization ◽  
Anticancer Compounds ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Forest Plants

This review is about the isolation as well as chemical and biological characterization of simple and complex mono-, sesqui-, di-, sester- and tri-terpenes produced by fungal pathogens of agrarian and forest plants and by some allelopathic plants. In several cases, the structure activity relationships are also discussed, as well as their potential application in agriculture as natural safe herbicides, fungicides and bactericides. Furthermore, the potential application of some fungal terpenes as anticancer compounds with a new mode of action is also discussed.

Design, Synthesis, and Biological Characterization of Bivalent 1-Methyl-1,2,5,6-tetrahydropyridyl-1,2,5-thiadiazole Derivatives as Selective Muscarinic Agonists

2001 ◽  
Vol 44 (26) ◽  
pp. 4563-4576 ◽  
Author(s):  
W. G. Rajeswaran ◽  
Yang Cao ◽  
Xi-Ping Huang ◽  
Mary Elizabeth Wroblewski ◽  
Tracy Colclough ◽  
...  
Keyword(s):  
Biological Characterization ◽  
Muscarinic Agonists ◽  
Design Synthesis ◽  
Thiadiazole Derivatives
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