Development of Dual-Acting Agents for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition. 3. Synthesis and Biological Activities of Oxazolecarboxamide-Substituted ω-Phenyl-ω-(3-pyridyl)alkenoic Acid Derivatives and Related Compounds

1998 ◽  
Vol 41 (27) ◽  
pp. 5362-5374 ◽  
Author(s):  
Kumiko Takeuchi ◽  
Todd J. Kohn ◽  
Timothy A. True ◽  
Dale E. Mais ◽  
James H. Wikel ◽  
...  
Keyword(s):  
Biological Activities ◽  
Thromboxane Synthase ◽  
Receptor Antagonism ◽  
Thromboxane Receptor ◽  
Alkenoic Acid ◽  
Related Compounds

Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 4. 8-[[(4-Chlorophenyl)sulfonyl]amino]-4-[3-(3-pyridinyl)propyl]octanoic acid and analogs

1992 ◽  
Vol 35 (23) ◽  
pp. 4373-4383 ◽  
Author(s):  
Shripad S. Bhagwat ◽  
Candido Gude ◽  
Clay Boswell ◽  
Nicolina Contardo ◽  
David S. Cohen ◽  
...  
Keyword(s):  
Octanoic Acid ◽  
Thromboxane Synthase ◽  
Receptor Antagonism ◽  
Thromboxane Receptor

N-tert-Butyl-N′-(2-cyclohexylamino-5-nitrobenzenesulfonyl)urea, BM531, a Dual-Acting Agent for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition.

ChemInform ◽  
2003 ◽  
Vol 34 (7) ◽  
Author(s):  
Catherine Michaux ◽  
Jean-Michel Dogne ◽  
Bernadette Norberg ◽  
Francois Durant ◽  
Bernard Masereel
Keyword(s):  
Thromboxane Synthase ◽  
Receptor Antagonism ◽  
Tert Butyl ◽  
Thromboxane Receptor ◽  
Acting Agent

ChemInform Abstract: Terbogrel, a Dual-Acting Agent for Thromboxane Receptor Antagonism and Thromboxane Synthase Inhibition.

ChemInform ◽  
2001 ◽  
Vol 32 (6) ◽  
pp. no-no
Author(s):  
Catherine Michaux ◽  
Bernadette Norberg ◽  
Jean-Michel Dogne ◽  
Francois Durant ◽  
Bernard Masereel ◽  
...  
Keyword(s):  
Thromboxane Synthase ◽  
Receptor Antagonism ◽  
Thromboxane Receptor ◽  
Acting Agent
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