Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 3.12-[ω-(4-Arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines:  Study of the Influence of the Terminal Amide Fragment on 5-HT1AAffinity/Selectivity

1997 ◽  
Vol 40 (16) ◽  
pp. 2653-2656 ◽  
Author(s):  
María L. López-Rodríguez ◽  
M. José Morcillo ◽  
Esther Fernández ◽  
Esther Porras ◽  
Marta Murcia ◽  
...  
Keyword(s):  
New Model ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Amide Fragment

Synthesis and structure–activity relationships of a new model of arylpiperazines. Part 7: Study of the influence of lipophilic factors at the terminal amide fragment on 5-HT1A affinity/selectivity

2004 ◽  
Vol 12 (6) ◽  
pp. 1551-1557 ◽  
Author(s):  
Marı́a L López-Rodrı́guez ◽  
David Ayala ◽  
Alma Viso ◽  
Bellinda Benhamú ◽  
Roberto Fernández de la Pradilla ◽  
...  
Keyword(s):  
New Model ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Amide Fragment

Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 8.1Computational Simulation of Ligand−Receptor Interaction of 5-HT1AR Agonists with Selectivity over α1-Adrenoceptors

2005 ◽  
Vol 48 (7) ◽  
pp. 2548-2558 ◽  
Author(s):  
María L. López-Rodríguez ◽  
Maria José Morcillo ◽  
Esther Fernández ◽  
Bellinda Benhamú ◽  
Ignacio Tejada ◽  
...  
Keyword(s):  
Receptor Interaction ◽  
New Model ◽  
Structure Activity Relationships ◽  
Structure Activity

Mixed 5-HT1A/D-2 activity of a new model of arylpiperazines: 1-aryl-4-[3-(1,2-dihydronaphthalen-4-yl)-n-propyl]piperazines. 1. Synthesis and structure-activity relationships

1994 ◽  
Vol 37 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Roberto Perrone ◽  
Francesco Berardi ◽  
Nicola A. Colabufo ◽  
Vincenzo Tortorella ◽  
Francesco Fiorentini ◽  
...  
Keyword(s):  
New Model ◽  
Structure Activity Relationships ◽  
Structure Activity

Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 1. 2-[[4-(o-Methoxyphenyl)piperazin-1-yl]methyl]-1,3- dioxoperhydroimidazo[1,5-a]pyridine:  A Selective 5-HT1AReceptor Agonist

1996 ◽  
Vol 39 (22) ◽  
pp. 4439-4450 ◽  
Author(s):  
María L. López-Rodríguez ◽  
M Luisa Rosado ◽  
Bellinda Benhamú ◽  
M José Morcillo ◽  
Antonio M. Sanz ◽  
...  
Keyword(s):  
New Model ◽  
Structure Activity Relationships ◽  
Structure Activity
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