Discovery and Optimization of a Novel Class of Orally Active Nonpeptidic Endothelin-A Receptor Antagonists

1996 ◽  
Vol 39 (11) ◽  
pp. 2123-2128 ◽  
Author(s):  
Hartmut Riechers ◽  
Hans-Peter Albrecht ◽  
Willi Amberg ◽  
Ernst Baumann ◽  
Harald Bernard ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active

scholarly journals Ethenesulfonamide Derivatives, a Novel Class of Orally Active Endothelin-A Receptor Antagonists

2001 ◽  
Vol 49 (5) ◽  
pp. 606-612 ◽  
Author(s):  
Hironori HARADA ◽  
Jun-ichi KAZAMI ◽  
Susumu WATANUKI ◽  
Ryuji TSUZUKI ◽  
Katsumi SUDOH ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active

ChemInform Abstract: Ethenesulfonamide Derivatives, a Novel Class of Orally Active Endothelin-A Receptor Antagonists.

ChemInform ◽  
2010 ◽  
Vol 32 (46) ◽  
pp. no-no
Author(s):  
Hironori Harada ◽  
Jun-ichi Kazami ◽  
Susumu Watanuki ◽  
Ryuji Tsuzuki ◽  
Katsumi Sudoh ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active

Ethenesulfonamide and ethanesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists

2001 ◽  
Vol 9 (11) ◽  
pp. 2955-2968 ◽  
Author(s):  
Hironori Harada ◽  
Jun-ichi Kazami ◽  
Susumu Watanuki ◽  
Ryuji Tsuzuki ◽  
Katsumi Sudoh ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active

ChemInform Abstract: 1,3-Disubstituted-2-carboxy Quinolones: Highly Potent and Selective Endothelin A Receptor Antagonists.

ChemInform ◽  
2000 ◽  
Vol 31 (42) ◽  
pp. no-no
Author(s):  
Jean-Luc Haesslein ◽  
Isabelle Baholet ◽  
Michel Fortin ◽  
Alain Iltis ◽  
Jean Khider ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A

Morphine tolerance does not develop in mice treated with endothelin-A receptor antagonists

2005 ◽  
Vol 1064 (1-2) ◽  
pp. 126-135 ◽  
Author(s):  
Shaifali Bhalla ◽  
George Matwyshyn ◽  
Anil Gulati
Keyword(s):  
Morphine Tolerance ◽  
Receptor Antagonists ◽  
Endothelin A Receptor ◽  
Endothelin A

Safety and efficacy of an orally active selective endothelin—A receptor antagonist in moderate-severe human chronic heart failure

1999 ◽  
Vol 5 (3) ◽  
pp. 48
Author(s):  
Horng H. Chen ◽  
Lisa M. Salz ◽  
Linda J. McKinley ◽  
Lyle J. Olson ◽  
Daniel D. Borgeson ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Receptor Antagonist ◽  
Safety And Efficacy ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active

Improvement of Postischemic Acute Renal Failure with the Novel Orally Active Endothelin-A Receptor Antagonist LU 135252 in the Rat

1998 ◽  
Vol 32 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Rainer Birck ◽  
Thomas Knoll ◽  
Claude Braun ◽  
Michael Kirchengast ◽  
Klaus Münter ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Receptor Antagonist ◽  
The Novel ◽  
Endothelin A Receptor ◽  
Endothelin A ◽  
Orally Active
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