Chiral Pyrrolo[2,3-d]pyrimidine and Pyrimido[4,5-b]indole Derivatives:  Structure−Activity Relationships of Potent, Highly Stereoselective A1-Adenosine Receptor Antagonists†,‡

Christa E. Müller; Uli Geis; Bettina Grahner; Wolfgang Lanzner; Kurt Eger

doi:10.1021/jm960011w

Chiral Pyrrolo[2,3-d]pyrimidine and Pyrimido[4,5-b]indole Derivatives: Structure−Activity Relationships of Potent, Highly Stereoselective A1-Adenosine Receptor Antagonists†,‡

Journal of Medicinal Chemistry ◽

10.1021/jm960011w ◽

1996 ◽

Vol 39 (13) ◽

pp. 2482-2491 ◽

Cited By ~ 23

Author(s):

Christa E. Müller ◽

Uli Geis ◽

Bettina Grahner ◽

Wolfgang Lanzner ◽

Kurt Eger

Keyword(s):

Adenosine Receptor ◽

Indole Derivatives ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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ChemInform Abstract: Chiral Pyrrolo(2,3-d)pyrimidine and Pyrimido(4,5-b)indole Derivatives: Structure-Activity Relationships of Potent, Highly Stereoselective A1- Adenosine Receptor Antagonists.

ChemInform ◽

10.1002/chin.199639180 ◽

2010 ◽

Vol 27 (39) ◽

pp. no-no

Author(s):

C. E. MUELLER ◽

U. GEIS ◽

B. GRAHNER ◽

W. LANZNER ◽

K. EGER

Keyword(s):

Adenosine Receptor ◽

Indole Derivatives ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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Structure–activity relationships in a series of 8-substituted xanthines as A1-adenosine receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(00)00271-6 ◽

2001 ◽

Vol 9 (3) ◽

pp. 575-583 ◽

Cited By ~ 11

Author(s):

Giovannella Strappaghetti ◽

Stefano Corsano ◽

Roberta Barbaro ◽

Gino Giannaccini ◽

Laura Betti

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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Structure-Activity Relationships in a Series of 8-Substituted Xanthines as Bronchodilator and A1-Adenosine Receptor Antagonists

Archiv der Pharmazie ◽

10.1002/ardp.19953280905 ◽

1995 ◽

Vol 328 (9) ◽

pp. 654-658 ◽

Cited By ~ 12

Author(s):

Stefano Corsano ◽

Giovannella Strappaghetti ◽

Rossana Scapicchi ◽

Antonio Lucacchini ◽

Generoso Senatore

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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ChemInform Abstract: Structure-Activity Relationships in a Series of 8-Substituted Xanthines as Bronchodilator and A1-Adenosine Receptor Antagonists.

ChemInform ◽

10.1002/chin.199604182 ◽

2010 ◽

Vol 27 (4) ◽

pp. no-no

Author(s):

S. CORSANO ◽

G. STRAPPAGHETTI ◽

R. SCAPICCHI ◽

A. LUCACCHINI ◽

G. SENATORE

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity ◽

Abstract Structure

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Synthesis and Structure-Activity Relationships of 4-Cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one Derivatives as A1 and A3 Adenosine Receptor Antagonists

Archiv der Pharmazie ◽

10.1002/ardp.200300816 ◽

2004 ◽

Vol 337 (1) ◽

pp. 35-41 ◽

Cited By ~ 6

Author(s):

Vittoria Colotta ◽

Daniela Catarzi ◽

Flavia Varano ◽

Guido Filacchioni ◽

Claudia Martini ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity ◽

A3 Adenosine Receptor

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Structure–Activity Relationships and Molecular Modeling of 1,2,4-Triazoles as Adenosine Receptor Antagonists

ACS Medicinal Chemistry Letters ◽

10.1021/ml300097g ◽

2012 ◽

Vol 3 (9) ◽

pp. 715-720 ◽

Cited By ~ 14

Author(s):

Jens Carlsson ◽

Dilip K. Tosh ◽

Khai Phan ◽

Zhan-Guo Gao ◽

Kenneth A. Jacobson

Keyword(s):

Molecular Modeling ◽

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow

Biochemical Pharmacology ◽

10.1016/0006-2952(86)90042-0 ◽

1986 ◽

Vol 35 (15) ◽

pp. 2467-2481 ◽

Cited By ~ 67

Author(s):

John W. Daly ◽

William Padgett ◽

Robert D. Thompson ◽

Shozo Kusachi ◽

William J. Bugni ◽

...

Keyword(s):

Blood Flow ◽

Coronary Blood Flow ◽

Adenosine Receptor ◽

A1 Adenosine Receptor ◽

Structure Activity Relationships ◽

Structure Activity

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Synthesis and Structure−Activity Relationships of a New Set of 2-Arylpyrazolo[3,4-c]quinoline Derivatives as Adenosine Receptor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm000936i ◽

2000 ◽

Vol 43 (16) ◽

pp. 3118-3124 ◽

Cited By ~ 54

Author(s):

Vittoria Colotta ◽

Daniela Catarzi ◽

Flavia Varano ◽

Lucia Cecchi ◽

Guido Filacchioni ◽

...

Keyword(s):

Adenosine Receptor ◽

Quinoline Derivatives ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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Structure–activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2009.03.034 ◽

2009 ◽

Vol 17 (10) ◽

pp. 3733-3738 ◽

Cited By ~ 13

Author(s):

Shantanu Pal ◽

Won Jun Choi ◽

Seung Ah Choe ◽

Cara L. Heller ◽

Zhan-Guo Gao ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity ◽

A3 Adenosine Receptor ◽

Adenosine Derivatives

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2-Amino[1,2,4]triazolo[1,5-c]quinazolines and Derived Novel Heterocycles: Syntheses and Structure-Activity Relationships of Potent Adenosine Receptor Antagonists

ChemMedChem ◽

10.1002/cmdc.201600255 ◽

2016 ◽

Vol 11 (20) ◽

pp. 2272-2286 ◽

Cited By ~ 11

Author(s):

Joachim C. Burbiel ◽

Wadih Ghattas ◽

Petra Küppers ◽

Meryem Köse ◽

Svenja Lacher ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity

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