New Selective Inhibitors of Steroid 11β-Hydroxylation in the Adrenal Cortex. Synthesis and Structure−Activity Relationship of Potent Etomidate Analogues

Ilse M. Zolle; Michael L. Berger; Friedrich Hammerschmidt; Stefanie Hahner; Andreas Schirbel; Biljana Peric-Simov

doi:10.1021/jm800920y

New Selective Inhibitors of Steroid 11β-Hydroxylation in the Adrenal Cortex. Synthesis and Structure−Activity Relationship of Potent Etomidate Analogues

Journal of Medicinal Chemistry ◽

10.1021/jm800920y ◽

2008 ◽

Vol 51 (23) ◽

pp. 7652-7652

Author(s):

Ilse M. Zolle ◽

Michael L. Berger ◽

Friedrich Hammerschmidt ◽

Stefanie Hahner ◽

Andreas Schirbel ◽

...

Keyword(s):

Adrenal Cortex ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of

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New Selective Inhibitors of Steroid 11β-Hydroxylation in the Adrenal Cortex. Synthesis and Structure–Activity Relationship of Potent Etomidate Analogues

Journal of Medicinal Chemistry ◽

10.1021/jm800012w ◽

2008 ◽

Vol 51 (7) ◽

pp. 2244-2253 ◽

Cited By ~ 29

Author(s):

Ilse M. Zolle ◽

Michael L. Berger ◽

Friedrich Hammerschmidt ◽

Stefanie Hahner ◽

Andreas Schirbel ◽

...

Keyword(s):

Adrenal Cortex ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of

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Design and Quantitative Structure−Activity Relationship of 3-Amidinobenzyl-1H-indole-2-carboxamides as Potent, Nonchiral, and Selective Inhibitors of Blood Coagulation Factor Xa

Journal of Medicinal Chemistry ◽

10.1021/jm0111346 ◽

2002 ◽

Vol 45 (13) ◽

pp. 2749-2769 ◽

Cited By ~ 58

Author(s):

Hans Matter ◽

Elisabeth Defossa ◽

Uwe Heinelt ◽

Peter-Michael Blohm ◽

Detlev Schneider ◽

...

Keyword(s):

Blood Coagulation ◽

Factor Xa ◽

Coagulation Factor ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of

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STRUCTURE-ACTIVITY RELATIONSHIP OF SELECTIVE INHIBITORS OF MAO-B

Monoamine Oxidases and their Selective Inhibition ◽

10.1016/b978-0-08-026389-2.50008-1 ◽

1980 ◽

pp. 11-21 ◽

Cited By ~ 4

Author(s):

K. Magyar ◽

Z. Ecseri ◽

G. Bernath ◽

Eva Satory ◽

J. Knoll

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Mao B ◽

Structure Activity ◽

Relationship Of

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Synthesis, Design, and Structure–Activity Relationship of the Pyrimidone Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

Molecules ◽

10.3390/molecules23061254 ◽

2018 ◽

Vol 23 (6) ◽

pp. 1254 ◽

Cited By ~ 5

Author(s):

Le Xu ◽

Wenjie Li ◽

Yanyan Diao ◽

Hongxia Sun ◽

Honglin Li ◽

...

Keyword(s):

Plasmodium Falciparum ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Dihydroorotate Dehydrogenase ◽

Selective Inhibitors ◽

Synthesis Design ◽

Structure Activity ◽

Relationship Of

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ChemInform Abstract: Synthesis and Structure-Activity Relationship of Diarylamide Derivatives as Selective Inhibitors of the Proliferation of Human Coronary Artery Smooth Muscle Cells.

ChemInform ◽

10.1002/chin.200123079 ◽

2010 ◽

Vol 32 (23) ◽

pp. no-no

Author(s):

Haruhisa Ogita ◽

Yoshiaki Isobe ◽

Haruo Takaku ◽

Rena Sekine ◽

Yuso Goto ◽

...

Keyword(s):

Smooth Muscle ◽

Coronary Artery ◽

Smooth Muscle Cells ◽

Muscle Cells ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Human Coronary Artery ◽

Structure Activity ◽

Relationship Of

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Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.11.066 ◽

2014 ◽

Vol 24 (2) ◽

pp. 654-660 ◽

Cited By ~ 14

Author(s):

Xiang-Yang Ye ◽

David Yoon ◽

Stephanie Y. Chen ◽

Akbar Nayeem ◽

Rajasree Golla ◽

...

Keyword(s):

Hydroxysteroid Dehydrogenase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of

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Discovery and structure–activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.05.006 ◽

2012 ◽

Vol 22 (13) ◽

pp. 4358-4361 ◽

Cited By ~ 11

Author(s):

Nobuhiro Fuchi ◽

Yosuke Iura ◽

Hiroaki Kaneko ◽

Aiko Nitta ◽

Kazuharu Suyama ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase Ck2 ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of ◽

Kinase Ck2

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Synthesis and Structure—Activity Relationship of a New Series of COX-2 Selective Inhibitors: 1,5-Diarylimidazoles.

ChemInform ◽

10.1002/chin.200345104 ◽

2003 ◽

Vol 34 (45) ◽

Author(s):

Carmen Almansa ◽

et al. et al.

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Cox 2 ◽

Relationship Of

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Selective Inhibitors of Monoamine Oxidase. 3. Structure−Activity Relationship of Tricyclics Bearing Imidazoline, Oxadiazole, or Tetrazole Groups

Journal of Medicinal Chemistry ◽

10.1021/jm950595m ◽

1996 ◽

Vol 39 (9) ◽

pp. 1857-1863 ◽

Cited By ~ 63

Author(s):

Morton Harfenist ◽

Darryl J. Heuser ◽

Charles T. Joyner ◽

John F. Batchelor ◽

Helen L. White

Keyword(s):

Monoamine Oxidase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Structure Activity ◽

Relationship Of

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Synthesis and structure–activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(00)00717-4 ◽

2001 ◽

Vol 11 (4) ◽

pp. 549-551 ◽

Cited By ~ 8

Author(s):

Haruhisa Ogita ◽

Yoshiaki Isobe ◽

Haruo Takaku ◽

Rena Sekine ◽

Yuso Goto ◽

...

Keyword(s):

Smooth Muscle ◽

Coronary Artery ◽

Smooth Muscle Cells ◽

Muscle Cells ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Selective Inhibitors ◽

Human Coronary Artery ◽

Structure Activity ◽

Relationship Of

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