Discovery and Evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity

2008 ◽  
Vol 51 (19) ◽  
pp. 5897-5900 ◽  
Author(s):  
Upender Velaparthi ◽  
Mark Wittman ◽  
Peiying Liu ◽  
Joan M. Carboni ◽  
Francis Y. Lee ◽  
...  
Keyword(s):  
Growth Factor ◽  
Antitumor Activity ◽  
Broad Spectrum ◽  
Insulin Like Growth Factor ◽  
Receptor Kinase ◽  
In Vivo Antitumor Activity

scholarly journals Antitumor Activity of the Insulin-Like Growth Factor-I Receptor Kinase Inhibitor NVP-AEW541 in Musculoskeletal Tumors

2005 ◽  
Vol 65 (9) ◽  
pp. 3868-3876 ◽  
Author(s):  
Katia Scotlandi ◽  
Maria Cristina Manara ◽  
Giordano Nicoletti ◽  
Pier-Luigi Lollini ◽  
Stella Lukas ◽  
...  
Keyword(s):  
Growth Factor ◽  
Antitumor Activity ◽  
Kinase Inhibitor ◽  
Insulin Like Growth Factor ◽  
Receptor Kinase ◽  
Factor I ◽  
Musculoskeletal Tumors ◽  
Growth Factor I
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