scholarly journals wALADin Benzimidazoles Differentially Modulate the Function of Porphobilinogen Synthase Orthologs

2014 ◽  
Vol 57 (6) ◽  
pp. 2498-2510 ◽  
Author(s):  
Christian S. Lentz ◽  
Victoria S. Halls ◽  
Jeffrey S. Hannam ◽  
Silke Strassel ◽  
Sarah H. Lawrence ◽  
...  
Keyword(s):  
Porphobilinogen Synthase

scholarly journals Mechanism of porphobilinogen synthase. Requirement of Zn2+ for enzyme activity.

1980 ◽  
Vol 255 (5) ◽  
pp. 2030-2035
Author(s):  
D.R. Bevan ◽  
P. Bodlaender ◽  
D. Shemin
Keyword(s):  
Enzyme Activity ◽  
Porphobilinogen Synthase

scholarly journals Mechanism of porphobilinogen synthase. Possible role of essential thiol groups.

1977 ◽  
Vol 252 (24) ◽  
pp. 8965-8974 ◽  
Author(s):  
G.F. Barnard ◽  
R. Itoh ◽  
L.H. Hohberger ◽  
D. Shemin
Keyword(s):  
Thiol Groups ◽  
Porphobilinogen Synthase

Structure of Porphobilinogen Synthase from Pseudomonas aeruginosa in Complex with 5-Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism

2002 ◽  
Vol 320 (2) ◽  
pp. 237-247 ◽  
Author(s):  
Frederic Frère ◽  
Wolf-Dieter Schubert ◽  
Frédéric Stauffer ◽  
Nicole Frankenberg ◽  
Reinhard Neier ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Schiff Base ◽  
Base Mechanism ◽  
Porphobilinogen Synthase

Probing the active site of rat porphobilinogen synthase using newly developed inhibitors

2009 ◽  
Vol 37 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Nan Li ◽  
Xiusheng Chu ◽  
Xiaojun Liu ◽  
Ding Li
Keyword(s):  
Active Site ◽  
Porphobilinogen Synthase

Kinetics and Thermodynamics of the Interchange of the Morpheein Forms of Human Porphobilinogen Synthase†

Biochemistry ◽  
2008 ◽  
Vol 47 (10) ◽  
pp. 3245-3257 ◽  
Author(s):  
Trevor Selwood ◽  
Lei Tang ◽  
Sarah H. Lawrence ◽  
Yana Anokhina ◽  
Eileen K. Jaffe
Keyword(s):  
Kinetics And Thermodynamics ◽  
Porphobilinogen Synthase
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