Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

2012 ◽  
Vol 55 (21) ◽  
pp. 9331-9345 ◽  
Author(s):  
Mihirbaran Mandal ◽  
Zhaoning Zhu ◽  
Jared N. Cumming ◽  
Xiaoxiang Liu ◽  
Corey Strickland ◽  
...  
Keyword(s):  
Beta Amyloid ◽  
Bioactive Conformation ◽  
Conformational Constraint

The neuroprotective effects of flupirtine and beta-amyloid induced memory impairment

2011 ◽  
Author(s):  
Matthew Jefferson ◽  
Sara Smeltzer ◽  
Jeffery L. McMillin ◽  
Caitlin C. Henry ◽  
Brittney M. Klauser ◽  
...  
Keyword(s):  
Memory Impairment ◽  
Beta Amyloid ◽  
Neuroprotective Effects

In vivo imaging of beta-amyloid load in transgenic rodents with [F-18]FDDNP microPET

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S588-S588
Author(s):  
Vladimir Kepe ◽  
Gregory M Cole ◽  
Jie Liu ◽  
Dorothy G Flood ◽  
Stephen P Trusko ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Beta Amyloid ◽  
Amyloid Load

Centella asiatica Protects Against the Toxic Effects of Intracellular beta-amyloid Accumulation

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
N Gray ◽  
J Morré ◽  
J Kelley ◽  
C Maier ◽  
F Stevens ◽  
...  
Keyword(s):  
Centella Asiatica ◽  
Beta Amyloid ◽  
Toxic Effects ◽  
Amyloid Accumulation

As a (white) matter of fact – Different white matter properties of beta-amyloid PET tracers

2020 ◽  
Author(s):  
M Rullmann ◽  
PL Flender ◽  
V Villemagne ◽  
O Sabri ◽  
H Barthel
Keyword(s):  
White Matter ◽  
Beta Amyloid ◽  
Amyloid Pet ◽  
Pet Tracers

Entzündung und Akkumulation von beta-Amyloid: Pathomechanistische Vernetzung bei der Einschlusskörperchenmyositis

2007 ◽  
Vol 34 (S 2) ◽  
Author(s):  
J Schmidt ◽  
K Barthel ◽  
M Bähr ◽  
R Gold ◽  
MC Dalakas
Keyword(s):  
Beta Amyloid
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