Synthesis and Evaluation of Novel18F Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques

Mengchao Cui; Xuedan Wang; Pingrong Yu; Jinming Zhang; Zijing Li; Xiaojun Zhang; Yanping Yang; Masahiro Ono; Hongmei Jia; Hideo Saji; Boli Liu

doi:10.1021/jm300973k

Synthesis and Evaluation of Novel18F Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques

Journal of Medicinal Chemistry ◽

10.1021/jm300973k ◽

2012 ◽

Vol 55 (21) ◽

pp. 9283-9296 ◽

Cited By ~ 32

Author(s):

Mengchao Cui ◽

Xuedan Wang ◽

Pingrong Yu ◽

Jinming Zhang ◽

Zijing Li ◽

...

Keyword(s):

Positron Emission Tomography ◽

Pet Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Novel18F-Labeled Benzofuran Derivatives with Improved Properties for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques in Alzheimer’s Brains

Journal of Medicinal Chemistry ◽

10.1021/jm200057u ◽

2011 ◽

Vol 54 (8) ◽

pp. 2971-2979 ◽

Cited By ~ 60

Author(s):

Masahiro Ono ◽

Yan Cheng ◽

Hiroyuki Kimura ◽

Mengchao Cui ◽

Shinya Kagawa ◽

...

Keyword(s):

Positron Emission Tomography ◽

Pet Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of β-amyloid plaques by positron emission tomography

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.09.028 ◽

2015 ◽

Vol 104 ◽

pp. 86-96 ◽

Cited By ~ 3

Author(s):

Yanping Yang ◽

Hualong Fu ◽

Mengchao Cui ◽

Cheng Peng ◽

Zhigang Liang ◽

...

Keyword(s):

Positron Emission Tomography ◽

Amyloid Plaques ◽

Emission Tomography ◽

Preliminary Evaluation ◽

Positron Emission ◽

Β Amyloid

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Validation of an 18F-labeled biphenylalkyne as a positron emission tomography imaging agent for β-amyloid plaques

Nuclear Medicine and Biology ◽

10.1016/j.nucmedbio.2009.01.013 ◽

2009 ◽

Vol 36 (4) ◽

pp. 411-417 ◽

Cited By ~ 7

Author(s):

Shiaw-Pyng Wey ◽

Chi-Chang Weng ◽

Kun-Ju Lin ◽

Cheng-Hsiang Yao ◽

Tzu-Chen Yen ◽

...

Keyword(s):

Positron Emission Tomography ◽

Positron Emission Tomography Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Imaging Agent ◽

Tomography Imaging ◽

Positron Emission ◽

Β Amyloid

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18F-Labeled 2-phenylquinoxaline derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2012.08.031 ◽

2012 ◽

Vol 57 ◽

pp. 51-58 ◽

Cited By ~ 6

Author(s):

Pingrong Yu ◽

Mengchao Cui ◽

Xuedan Wang ◽

Xiaojun Zhang ◽

Zijing Li ◽

...

Keyword(s):

Positron Emission Tomography ◽

In Vivo Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Novel18F-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral β-Amyloid Plaques in Alzheimer’s Disease

Journal of Medicinal Chemistry ◽

10.1021/jm300251n ◽

2012 ◽

Vol 55 (21) ◽

pp. 9136-9145 ◽

Cited By ~ 31

Author(s):

Mengchao Cui ◽

Masahiro Ono ◽

Hiroyuki Kimura ◽

Masashi Ueda ◽

Yuji Nakamoto ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Positron Emission Tomography ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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18F-Labeled Benzyldiamine Derivatives as Novel Flexible Probes for Positron Emission Tomography of Cerebral β-Amyloid Plaques

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.6b01063 ◽

2016 ◽

Vol 59 (23) ◽

pp. 10577-10585 ◽

Cited By ~ 2

Author(s):

Zijing Li ◽

Xuran Zhang ◽

Xiaoyang Zhang ◽

Mengchao Cui ◽

Jie Lu ◽

...

Keyword(s):

Positron Emission Tomography ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Fluoro-pegylated Chalcones as Positron Emission Tomography Probes for in Vivo Imaging of β-Amyloid Plaques in Alzheimer’s Disease

Journal of Medicinal Chemistry ◽

10.1021/jm901057p ◽

2009 ◽

Vol 52 (20) ◽

pp. 6394-6401 ◽

Cited By ~ 51

Author(s):

Masahiro Ono ◽

Rumi Watanabe ◽

Hidekazu Kawashima ◽

Yan Cheng ◽

Hiroyuki Kimura ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Positron Emission Tomography ◽

In Vivo Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Naphthylethylidene Derivatives as Positron Emission Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer's Disease

Journal of Neuroscience ◽

10.1523/jneurosci.21-24-j0004.2001 ◽

2001 ◽

Vol 21 (24) ◽

pp. RC189-RC189 ◽

Cited By ~ 281

Author(s):

Eric D. Agdeppa ◽

Vladimir Kepe ◽

Jie Liu ◽

Samuel Flores-Torres ◽

Nagichettiar Satyamurthy ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Positron Emission Tomography ◽

Positron Emission Tomography Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Tomography Imaging ◽

Binding Characteristics ◽

Positron Emission ◽

Imaging Probes ◽

Β Amyloid

Download Full-text

Novel 18F-labeled dibenzylideneacetone derivatives as potential positron emission tomography probes for in vivo imaging of β-amyloid plaques

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.07.070 ◽

2014 ◽

Vol 84 ◽

pp. 628-638 ◽

Cited By ~ 6

Author(s):

Zijing Li ◽

Mengchao Cui ◽

Jinming Zhang ◽

Jiapei Dai ◽

Xiaojun Zhang ◽

...

Keyword(s):

Positron Emission Tomography ◽

In Vivo Imaging ◽

Amyloid Plaques ◽

Emission Tomography ◽

Positron Emission ◽

Β Amyloid

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Aromatic radiofluorination and biological evaluation of 2-aryl-6-[18F]fluorobenzothiazoles as a potential positron emission tomography imaging probe for β-amyloid plaques

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.03.029 ◽

2011 ◽

Vol 19 (9) ◽

pp. 2980-2990 ◽

Cited By ~ 20

Author(s):

Byung Chul Lee ◽

Ji Sun Kim ◽

Bom Sahn Kim ◽

Ji Yeon Son ◽

Soo Kyung Hong ◽

...

Keyword(s):

Positron Emission Tomography ◽

Positron Emission Tomography Imaging ◽

Amyloid Plaques ◽

Biological Evaluation ◽

Emission Tomography ◽

Tomography Imaging ◽

Imaging Probe ◽

Positron Emission ◽

Β Amyloid

Download Full-text