Discovery and Lead Optimization of a Novel Series of CC Chemokine Receptor 1 (CCR1)-Selective Piperidine Antagonists via Parallel Synthesis

2012 ◽  
Vol 55 (22) ◽  
pp. 9643-9653 ◽  
Author(s):  
Cullen L. Cavallaro ◽  
Stephanie Briceno ◽  
Jing Chen ◽  
Mary Ellen Cvijic ◽  
Paul Davies ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Parallel Synthesis ◽  
Lead Optimization ◽  
Cc Chemokine ◽  
Chemokine Receptor 1

scholarly journals Site-directed Mutagenesis of CC Chemokine Receptor 1 Reveals the Mechanism of Action of UCB 35625, a Small Molecule Chemokine Receptor Antagonist

2004 ◽  
Vol 280 (6) ◽  
pp. 4808-4816 ◽  
Author(s):  
Filipa Lopes de Mendonça ◽  
Paula C. A. da Fonseca ◽  
Rhian M. Phillips ◽  
José W. Saldanha ◽  
Timothy J. Williams ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Small Molecule ◽  
Mechanism Of Action ◽  
Chemokine Receptor ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Cc Chemokine ◽  
Chemokine Receptor Antagonist ◽  
Chemokine Receptor 1

CC chemokine receptor 1 enhances susceptibility to Leishmania major during early phase of infection

2003 ◽  
Vol 81 (2) ◽  
pp. 114-120 ◽  
Author(s):  
Miriam Rodriguez‐Sosa ◽  
Lucia E Rosas ◽  
Luis I Terrazas ◽  
Bao Lu ◽  
Craig Gerard ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Early Phase ◽  
Leishmania Major ◽  
Cc Chemokine ◽  
Chemokine Receptor 1
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