A Prospective Cross-Screening Study on G-Protein-Coupled Receptors: Lessons Learned in Virtual Compound Library Design

Marijn P. A. Sanders; Luc Roumen; Eelke van der Horst; J. Robert Lane; Henry F. Vischer; Jody van Offenbeek; Henk de Vries; Stefan Verhoeven; Ken Y. Chow; Folkert Verkaar; Margot W. Beukers; Ross McGuire; Rob Leurs; Adriaan P. IJzerman; Jacob de Vlieg; Iwan J. P. de Esch; Guido J. R. Zaman; Jan P. G. Klomp; Andreas Bender; Chris de Graaf

doi:10.1021/jm300280e

A Prospective Cross-Screening Study on G-Protein-Coupled Receptors: Lessons Learned in Virtual Compound Library Design

Journal of Medicinal Chemistry ◽

10.1021/jm300280e ◽

2012 ◽

Vol 55 (11) ◽

pp. 5311-5325 ◽

Cited By ~ 22

Author(s):

Marijn P. A. Sanders ◽

Luc Roumen ◽

Eelke van der Horst ◽

J. Robert Lane ◽

Henry F. Vischer ◽

...

Keyword(s):

G Protein ◽

Lessons Learned ◽

G Protein Coupled Receptors ◽

Library Design ◽

Compound Library ◽

Screening Study ◽

G Protein Coupled

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Naturally Occurring Mutations of the Luteinizing-Hormone Receptor: Lessons Learned about Reproductive Physiology and G Protein–Coupled Receptors

The American Journal of Human Genetics ◽

10.1086/302602 ◽

1999 ◽

Vol 65 (4) ◽

pp. 949-958 ◽

Cited By ~ 78

Author(s):

Ana Claudia Latronico ◽

Deborah L. Segaloff

Keyword(s):

Luteinizing Hormone ◽

G Protein ◽

Hormone Receptor ◽

Lessons Learned ◽

G Protein Coupled Receptors ◽

Reproductive Physiology ◽

Luteinizing Hormone Receptor ◽

Naturally Occurring ◽

G Protein Coupled

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Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

10.1016/s1877-1173(20)x0002-0 ◽

2020 ◽

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Health And Disease ◽

G Protein Coupled

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G Protein-Coupled Receptors Part A

10.1016/s0091-679x(17)x0006-x ◽

2017 ◽

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

G Protein Coupled

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G Protein-Coupled Receptors - Signaling, Trafficking and Regulation

10.1016/s0091-679x(16)x0002-7 ◽

2016 ◽

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

G Protein Coupled

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Enhanced Salmonella virulence instigated by bactivorous protozoa and investigation of putative protozoan G protein-coupled receptors associated with bacterial engulfment

10.31274/etd-180810-61 ◽

2014 ◽

Author(s):

Matt T. Brewer

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Salmonella Virulence ◽

G Protein Coupled

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Faculty Opinions recommendation of Modulation of postendocytic sorting of G protein-coupled receptors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1008239.104108 ◽

2002 ◽

Author(s):

Silvia Arber

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

G Protein Coupled

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Faculty Opinions recommendation of Proteochemometrics modeling of the interaction of amine G-protein coupled receptors with a diverse set of ligands.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007831.98556 ◽

2002 ◽

Author(s):

Wolfgang Guba

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

G Protein Coupled

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Faculty Opinions recommendation of Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1014169.192885 ◽

2003 ◽

Author(s):

Kees Jalink

Keyword(s):

G Protein ◽

Living Cells ◽

G Protein Coupled Receptors ◽

G Protein Coupled

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Faculty Opinions recommendation of A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by Gbetagamma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013618.191473 ◽

2003 ◽

Author(s):

Sandip Patel

Keyword(s):

G Protein ◽

G Protein Coupled Receptors ◽

Ip3 Receptor ◽

G Protein Coupled

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Faculty Opinions recommendation of Control of feeding behavior in C. elegans by human G protein-coupled receptors permits screening for agonist-expressing bacteria.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1125840.582940 ◽

2008 ◽

Author(s):

Sachdev Sidhu ◽

Raffi Tonikian

Keyword(s):

Feeding Behavior ◽

G Protein ◽

G Protein Coupled Receptors ◽

C Elegans ◽

G Protein Coupled

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