Identification and Structure–Activity Relationships of a Novel Series of Estrogen Receptor Ligands Based on 7-Thiabicyclo[2.2.1]hept-2-ene-7-oxide

Pengcheng Wang; Jian Min; Jerome C. Nwachukwu; Valerie Cavett; Kathryn E. Carlson; Pu Guo; Manghong Zhu; Yangfan Zheng; Chune Dong; John A. Katzenellenbogen; Kendall W. Nettles; Hai-Bing Zhou

doi:10.1021/jm201556r

Identification and Structure–Activity Relationships of a Novel Series of Estrogen Receptor Ligands Based on 7-Thiabicyclo[2.2.1]hept-2-ene-7-oxide

Journal of Medicinal Chemistry ◽

10.1021/jm201556r ◽

2012 ◽

Vol 55 (5) ◽

pp. 2324-2341 ◽

Cited By ~ 23

Author(s):

Pengcheng Wang ◽

Jian Min ◽

Jerome C. Nwachukwu ◽

Valerie Cavett ◽

Kathryn E. Carlson ◽

...

Keyword(s):

Estrogen Receptor ◽

Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity ◽

Estrogen Receptor Ligands

Download Full-text

Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure–activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides

Organic & Biomolecular Chemistry ◽

10.1039/c2ob26531a ◽

2012 ◽

Vol 10 (43) ◽

pp. 8692 ◽

Cited By ~ 21

Author(s):

Manghong Zhu ◽

Chen Zhang ◽

Jerome C. Nwachukwu ◽

Sathish Srinivasan ◽

Valerie Cavett ◽

...

Keyword(s):

Estrogen Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Structure Activity Relationships ◽

Structure Activity ◽

Estrogen Receptor Ligands

Download Full-text

ChemInform Abstract: Binary Quantitative Structure-Activity Relationship (QSAR) Analysis of Estrogen Receptor Ligands.

ChemInform ◽

10.1002/chin.199921263 ◽

2010 ◽

Vol 30 (21) ◽

pp. no-no

Author(s):

Hua Gao ◽

Chris Williams ◽

Paul Labute ◽

Juergen Bajorath

Keyword(s):

Estrogen Receptor ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Receptor Ligands ◽

Qsar Analysis ◽

Structure Activity ◽

Estrogen Receptor Ligands

Download Full-text

Novel estrogen receptor ligands and their structure-activity relationship evaluated by scintillation proximity assay for high-throughput screening

Drug Development Research ◽

10.1002/ddr.10435 ◽

2005 ◽

Vol 64 (4) ◽

pp. 203-212 ◽

Cited By ~ 1

Author(s):

Ling He ◽

Hua Xiang ◽

Lu-Yong Zhang ◽

Wei-Sheng Tian ◽

Hua-Hong He

Keyword(s):

Estrogen Receptor ◽

High Throughput ◽

High Throughput Screening ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

Scintillation Proximity Assay ◽

Structure Activity ◽

Estrogen Receptor Ligands

Download Full-text

Structure–activity relationship study of a diverse set of estrogen receptor ligands (I) using MultiCASE expert system

Chemosphere ◽

10.1016/s0045-6535(02)00859-7 ◽

2003 ◽

Vol 51 (6) ◽

pp. 445-459 ◽

Cited By ~ 32

Author(s):

Gilles Klopman ◽

Suman K. Chakravarti

Keyword(s):

Estrogen Receptor ◽

Expert System ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

Structure Activity ◽

Relationship Study ◽

Estrogen Receptor Ligands

Download Full-text

Structure-activity relationship model for estrogen receptor ligands.

10.18297/etd/1596 ◽

2012 ◽

Author(s):

Huihui Wu

Keyword(s):

Estrogen Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Receptor Ligands ◽

Structure Activity ◽

Relationship Model ◽

Estrogen Receptor Ligands

Download Full-text

Binary Quantitative Structure−Activity Relationship (QSAR) Analysis of Estrogen Receptor Ligands†

Journal of Chemical Information and Computer Sciences ◽

10.1021/ci980140g ◽

1999 ◽

Vol 39 (1) ◽

pp. 164-168 ◽

Cited By ~ 79

Author(s):

Hua Gao ◽

Chris Williams ◽

Paul Labute ◽

Jürgen Bajorath

Keyword(s):

Estrogen Receptor ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Receptor Ligands ◽

Qsar Analysis ◽

Structure Activity ◽

Estrogen Receptor Ligands

Download Full-text

Cyclopentadienyl Rhenium (Technetium) Tricarbonyl Complexes Integrated in Estrogen Receptor Ligands for ER+ Tumor Imaging

10.21236/ada456153 ◽

2005 ◽

Author(s):

Nathan C. Ackroyd ◽

John A. Katzenellenbogen

Keyword(s):

Estrogen Receptor ◽

Tumor Imaging ◽

Receptor Ligands ◽

Estrogen Receptor Ligands

Download Full-text

A Bipartite Recombinant Yeast System for the Identification of Subtype-Selective Estrogen Receptor Ligands

Molecular Biotechnology ◽

10.1007/s12033-008-9141-9 ◽

2009 ◽

Vol 41 (3) ◽

pp. 307-307

Author(s):

Kaiwei Liang ◽

Liuqing Yang ◽

Zhimin Xiao ◽

Jian Huang

Keyword(s):

Estrogen Receptor ◽

Recombinant Yeast ◽

Receptor Ligands ◽

Estrogen Receptor Ligands ◽

Subtype Selective

Download Full-text

Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding

ChemBioChem ◽

10.1002/cbic.201100529 ◽

2011 ◽

Vol 12 (17) ◽

pp. 2587-2598 ◽

Cited By ~ 22

Author(s):

Min Shan ◽

Alexander Bujotzek ◽

Frank Abendroth ◽

Anja Wellner ◽

Ronald Gust ◽

...

Keyword(s):

Estrogen Receptor ◽

Conformational Analysis ◽

Receptor Ligands ◽

Estrogen Receptor Ligands

Download Full-text

A Computationally Based Identification Algorithm for Estrogen Receptor Ligands: Part 2. Evaluation of a hERalpha Binding Affinity Model

Toxicological Sciences ◽

10.1093/toxsci/58.2.270 ◽

2000 ◽

Vol 58 (2) ◽

pp. 270-281 ◽

Cited By ~ 25

Author(s):

O. G. Mekenyan

Keyword(s):

Estrogen Receptor ◽

Binding Affinity ◽

Identification Algorithm ◽

Receptor Ligands ◽

Affinity Model ◽

Estrogen Receptor Ligands

Download Full-text