scholarly journals ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis

2011 ◽  
Vol 55 (1) ◽  
pp. 515-527 ◽  
Author(s):  
Tian Chen ◽  
Radhia Benmohamed ◽  
Jinho Kim ◽  
Karen Smith ◽  
Daniel Amante ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Superoxide Dismutase ◽  
Protein Aggregation ◽  
Potential Application ◽  
Superoxide Dismutase 1 ◽  
Design And Synthesis ◽  
Pyrazolone Derivatives ◽  
Lateral Sclerosis

scholarly journals Glial nuclear aggregates of superoxide dismutase-1 are regularly present in patients with amyotrophic lateral sclerosis

2011 ◽  
Vol 121 (5) ◽  
pp. 623-634 ◽  
Author(s):  
Karin Forsberg ◽  
Peter M. Andersen ◽  
Stefan L. Marklund ◽  
Thomas Brännström
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Superoxide Dismutase ◽  
Superoxide Dismutase 1 ◽  
Lateral Sclerosis

scholarly journals Phenotype of Transgenic Mice Carrying a Very Low Copy Number of the Mutant Human G93A Superoxide Dismutase-1 Gene Associated with Amyotrophic Lateral Sclerosis

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99879 ◽  
Author(s):  
Jeffrey S. Deitch ◽  
Guillermo M. Alexander ◽  
Andrew Bensinger ◽  
Steven Yang ◽  
Juliann T. Jiang ◽  
...  
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Superoxide Dismutase ◽  
Transgenic Mice ◽  
Copy Number ◽  
Superoxide Dismutase 1 ◽  
Low Copy Number ◽  
Lateral Sclerosis
Sign in / Sign up

Export Citation Format

Share Document