Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes

2011 ◽  
Vol 55 (1) ◽  
pp. 209-222 ◽  
Author(s):  
Nancy H. Campbell ◽  
Nurul H. Abd Karim ◽  
Gary N. Parkinson ◽  
Mekala Gunaratnam ◽  
Vanessa Petrucci ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Molecular Basis ◽  
Telomeric Dna ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Dna Quadruplexes

New Luminescent Polynuclear Metal Complexes with Anticancer Properties: Toward Structure–Activity Relationships

2016 ◽  
Vol 55 (5) ◽  
pp. 2544-2557 ◽  
Author(s):  
Margot Wenzel ◽  
Andreia de Almeida ◽  
Emilia Bigaeva ◽  
Paul Kavanagh ◽  
Michel Picquet ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Structure Activity Relationships ◽  
Anticancer Properties ◽  
Structure Activity ◽  
Polynuclear Metal Complexes

scholarly journals Thalidomide-type teratogenicity: structure–activity relationships for congeners

2018 ◽  
Vol 7 (6) ◽  
pp. 1036-1047 ◽  
Author(s):  
R. L. Smith ◽  
S. C. Mitchell
Keyword(s):  
Molecular Basis ◽  
Mature Animal ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Low Toxicity ◽  
Species Specific

Unravelling the molecular basis of thalidomide embryotoxicity, which is remarkably species-specific, is challenging in view of its low toxicity in the mature animal.

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