Three-Dimensional Quantitative Structure−Activity Relationships and Activity Predictions of Human TRPV1 Channel Antagonists:  Comparative Molecular Field Analysis and Comparative Molecular Similarity Index Analysis of Cinnamides

Vellarkad N. Viswanadhan; Yaxiong Sun; Mark H. Norman

doi:10.1021/jm070261k

Three-Dimensional Quantitative Structure−Activity Relationships and Activity Predictions of Human TRPV1 Channel Antagonists: Comparative Molecular Field Analysis and Comparative Molecular Similarity Index Analysis of Cinnamides

Journal of Medicinal Chemistry ◽

10.1021/jm070261k ◽

2007 ◽

Vol 50 (23) ◽

pp. 5608-5619 ◽

Cited By ~ 18

Author(s):

Vellarkad N. Viswanadhan ◽

Yaxiong Sun ◽

Mark H. Norman

Keyword(s):

Molecular Similarity ◽

Three Dimensional ◽

Similarity Index ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Trpv1 Channel ◽

Index Analysis ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Three-Dimensional Quantitative Structure-Activity Relationships of Somatostatin Analogs. 1. Comparative Molecular Field Analysis of Growth Hormone Release-Inhibiting Potencies

Journal of Medicinal Chemistry ◽

10.1021/jm00011a017 ◽

1995 ◽

Vol 38 (11) ◽

pp. 1974-1989 ◽

Cited By ~ 11

Author(s):

Simon J. Hocart ◽

Vik Reddy ◽

William A. Murphy ◽

David H. Coy

Keyword(s):

Growth Hormone ◽

Somatostatin Analogs ◽

Three Dimensional ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Hormone Release ◽

Growth Hormone Release ◽

Quantitative Structure ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Three Dimensional Quantitative Structure-Activity Relationships of Sulfonamides Binding Monoclonal Antibody by Comparative Molecular Field Analysis

Nature Precedings ◽

10.1038/npre.2008.2646.1 ◽

2008 ◽

Author(s):

Zhanhui Wang ◽

Xingyuan Cao ◽

Zhenpeng Kai ◽

Ross Beier ◽

Congming Wu ◽

...

Keyword(s):

Monoclonal Antibody ◽

Three Dimensional ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Molecular Field Analysis ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Three-Dimensional Quantitative Structure−Activity Relationships of Cyclo-oxygenase-2 (COX-2) Inhibitors: A Comparative Molecular Field Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm0101343 ◽

2001 ◽

Vol 44 (20) ◽

pp. 3223-3230 ◽

Cited By ~ 76

Author(s):

Philippe Chavatte ◽

Saïd Yous ◽

Christophe Marot ◽

Nicolas Baurin ◽

Daniel Lesieur

Keyword(s):

Three Dimensional ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Cox 2 ◽

Quantitative Structure Activity Relationships ◽

Cox 2 Inhibitors

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Three-Dimensional Quantitative Structure−Activity Relationship Analyses Using Comparative Molecular Field Analysis and Comparative Molecular Similarity Indices Analysis To Elucidate Selectivity Differences of Inhibitors Binding to Trypsin, Thrombin, and Factor Xa

Journal of Medicinal Chemistry ◽

10.1021/jm981062r ◽

1999 ◽

Vol 42 (3) ◽

pp. 458-477 ◽

Cited By ~ 327

Author(s):

Markus Böhm ◽

Jörg Stürzebecher ◽

Gerhard Klebe

Keyword(s):

Molecular Similarity ◽

Three Dimensional ◽

Factor Xa ◽

Quantitative Structure Activity Relationship ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Structure Activity ◽

Similarity Indices

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Three-dimensional quantitative structure–activity relationships study on HIV-1 reverse transcriptase inhibitors in the class of dipyridodiazepinone derivatives, using comparative molecular field analysis

Journal of Molecular Graphics and Modelling ◽

10.1016/s1093-3263(00)00053-x ◽

2000 ◽

Vol 18 (6) ◽

pp. 581-590 ◽

Cited By ~ 23

Author(s):

Pornpan Pungpo ◽

Supa Hannongbua

Keyword(s):

Reverse Transcriptase ◽

Three Dimensional ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Reverse Transcriptase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Hiv 1

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Three-Dimensional Quantitative Structure–Activity Relationship Analysis for Human Pregnane X Receptor for the Prediction of CYP3A4 Induction in Human Hepatocytes: Structure-Based Comparative Molecular Field Analysis

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24235 ◽

2015 ◽

Vol 104 (1) ◽

pp. 223-232 ◽

Cited By ~ 7

Author(s):

Koichi Handa ◽

Izumi Nakagome ◽

Noriyuki Yamaotsu ◽

Hiroaki Gouda ◽

Shuichi Hirono

Keyword(s):

Three Dimensional ◽

Pregnane X Receptor ◽

Quantitative Structure Activity Relationship ◽

Human Hepatocytes ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Cyp3a4 Induction

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Three-Dimensional Quantitative Structure-Activity Relationship (QSAR) of HIV Integrase Inhibitors: A Comparative Molecular Field Analysis (CoMFA) Study

Journal of Medicinal Chemistry ◽

10.1021/jm00006a006 ◽

1995 ◽

Vol 38 (6) ◽

pp. 890-897 ◽

Cited By ~ 60

Author(s):

K. Raghavan ◽

John K. Buolamwini ◽

Mark R. Fesen ◽

Yves Pommier ◽

Kurt W. Kohn ◽

...

Keyword(s):

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Hiv Integrase ◽

Quantitative Structure ◽

Integrase Inhibitors ◽

Structure Activity ◽

Hiv Integrase Inhibitors ◽

Comfa Study

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Three-Dimensional Quantitative Structure−Activity Relationship Study on Cyclic Urea Derivatives as HIV-1 Protease Inhibitors: Application of Comparative Molecular Field Analysis†

Journal of Medicinal Chemistry ◽

10.1021/jm980369n ◽

1999 ◽

Vol 42 (2) ◽

pp. 249-259 ◽

Cited By ~ 53

Author(s):

Asim Kumar Debnath

Keyword(s):

Protease Inhibitors ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Urea Derivatives ◽

Structure Activity ◽

Relationship Study ◽

Hiv 1

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A Three-Dimensional Quantitative Structure−Activity Relationship Study of Heparin-Binding Epidermal Growth Factor Shedding Inhibitors Using Comparative Molecular Field Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm0110385 ◽

2002 ◽

Vol 45 (4) ◽

pp. 781-788 ◽

Cited By ~ 7

Author(s):

Roberta Bursi ◽

Masaaki Sawa ◽

Yasuyuki Hiramatsu ◽

Hirosato Kondo

Keyword(s):

Growth Factor ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Field Analysis ◽

Comparative Molecular Field Analysis ◽

Heparin Binding ◽

Quantitative Structure ◽

Structure Activity ◽

Epidermal Growth ◽

Relationship Study

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Three-Dimensional Quantitative Structure-Activity Relationship Studies on UGT1A9-Mediated 3-O-Glucuronidation of Natural Flavonols Using a Pharmacophore-Based Comparative Molecular Field Analysis Model

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.175356 ◽

2010 ◽

Vol 336 (2) ◽

pp. 403-413 ◽

Cited By ~ 31

Author(s):

Baojian Wu ◽

John Kenneth Morrow ◽

Rashim Singh ◽

Shuxing Zhang ◽

Ming Hu

Keyword(s):

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Field Analysis ◽

Molecular Field ◽

Activity Relationship ◽

Comparative Molecular Field Analysis ◽

Quantitative Structure ◽

Analysis Model ◽

Structure Activity

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