Synthesis and Preliminary In vitro Investigation of Bivalent Ligands Containing Homo- and Heterodimeric Pharmacophores at μ, δ, and κ Opioid Receptors

2006 ◽  
Vol 49 (1) ◽  
pp. 256-262 ◽  
Author(s):  
Xuemei Peng ◽  
Brian I. Knapp ◽  
Jean M. Bidlack ◽  
John L. Neumeyer
Keyword(s):  
Opioid Receptors ◽  
Bivalent Ligands ◽  
In Vitro Investigation

scholarly journals In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors

2007 ◽  
Vol 15 (12) ◽  
pp. 4106-4112 ◽  
Author(s):  
Xuemei Peng ◽  
Brian I. Knapp ◽  
Jean M. Bidlack ◽  
John L. Neumeyer
Keyword(s):  
Opioid Receptors ◽  
In Vitro Investigation

In vitro investigation of Varizella zoster virus as an oncolytic virus in glioblastoma therapy

2008 ◽  
Vol 35 (S 01) ◽  
Author(s):  
H Leske ◽  
A Baiker ◽  
C Schichor ◽  
J.C Tonn ◽  
R Goldbrunner ◽  
...  
Keyword(s):  
Oncolytic Virus ◽  
In Vitro Investigation ◽  
Varizella Zoster Virus

An In Vitro Investigation of Synergy or Antagonism between Antimicrobial Combinations against Isolates from Bacterial Keratitis

2010 ◽  
Vol 51 (8) ◽  
pp. 4151 ◽  
Author(s):  
Henri Sueke ◽  
Stephen B. Kaye ◽  
Timothy Neal ◽  
Amanda Hall ◽  
Stephen Tuft ◽  
...  
Keyword(s):  
Bacterial Keratitis ◽  
In Vitro Investigation ◽  
Antimicrobial Combinations

Design and In vitro Investigation of Grafted Chitosan as Chitosan Nanoparticles Containing Deflazacort Drug Coated by Calcium Starch Glycolate

2020 ◽  
Vol 21 (12) ◽  
pp. 2718-2728
Author(s):  
Elsayed M. Abdel Bary ◽  
Ammar N. Harmal ◽  
Mona E. Ibrahim ◽  
Moustafa A. Gouda
Keyword(s):  
Chitosan Nanoparticles ◽  
In Vitro Investigation

scholarly journals In vitro investigation of laser-induced microgrooves on titanium surface

2020 ◽  
Vol 1571 ◽  
pp. 012010
Author(s):  
V P Veiko ◽  
Yu Yu Karlagina ◽  
E E Egorova ◽  
E A Zernitskaya ◽  
D S Kuznetsova ◽  
...  
Keyword(s):  
Titanium Surface ◽  
In Vitro Investigation

Mineral Density and Fluoride Content of in vitro Remineralized Lesions

1988 ◽  
Vol 67 (3) ◽  
pp. 577-581 ◽  
Author(s):  
Y. Jima ◽  
T. Koulourides
Keyword(s):  
Complete Recovery ◽  
Fluoride Content ◽  
Mineral Density ◽  
Acid Dissolution ◽  
Thin Sections ◽  
Partially Saturated ◽  
In Vitro Investigation ◽  
Bovine Enamel ◽  
Caries Lesions

This in vitro investigation studied the remineralization of experimental caries lesions in bovine enamel by use of three methods: (1) surface microhardness, (2) microradiography, and (3) abrasion biopsy for mineral density and fluoride content. The lesions were produced by a two-day exposure to 0.01 mol/L lactic acidlsodium hydroxide buffer partially saturated with 3.0 mmol/L Ca, 1.8 mmol/L P, in 1% CMC, at pH 4.0 and 37°C. The lesions were exposed to a remineralizing solution containing 3.0 mmol/L Ca, 1.8 mmol/L P, and 3 ppm F in 1% CMC at pH 7.0 and 37°C for two, six, and ten days, with solution changes every two days. The data derived from the three methods are presented in sequence from the baseline and at days two, six, and ten of the remineralizing treatment. Microhardness measurements showed hardness recoveries of 35.9, 78.9, and 87.5%, respectively. Microradiography suggested complete recovery with the ten-day remineralization. Abrasion biopsy of successive 10-μm layers to a depth of 100 μm indicated 15.2, 39.8, and 68.8% mineral density recoveries, with fluoride content of the surface layer increasing from a baseline of 300 ppm to 4600, 9000, and 9800 ppm F for the 2, 6, 10 days of remineralization, respectively. Subsequent acid-etching of thin sections from the ten-day-remineralized specimens showed that the fluoride-enriched remineralized area was more resistant to acid dissolution than was the underlying nonnal enamel.

In vitro investigation of calcium distribution and tissue thickness in the human thoracic aorta

2002 ◽  
Vol 23 (3) ◽  
pp. 555-566 ◽  
Author(s):  
P J Dunmore-Buyze ◽  
M Moreau ◽  
A Fenster ◽  
D W Holdsworth
Keyword(s):  
Thoracic Aorta ◽  
Tissue Thickness ◽  
Calcium Distribution ◽  
In Vitro Investigation
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